RESUMO
Objetivo. Evaluar la efectividad del uso de sucrosa en la prevención del dolor durante la punción venosa en neonatos. Método. Ensayo clínico controlado, doble ciego. La población estuvo constituida por todos los neonatos hospitalizados sometidos a venopunción. El tamaño de la muestra se calculó con una confianza del 95%, una potencia del 80%, una proporción mínima de neonatos con dolor del 40% en el grupo de estudio y del 70% en el grupo control. Bajo estas condiciones el tamaño de la muestra mínimo fue de 49 neonatos por grupo. Método. A los neonatos, cinco minutos antes de la punción venosa les fue administrado 1 cm3 de solución de sucrosa al 12% (grupo de estudio) o de agua destilada (grupo control placebo). Durante el procedimiento fue evaluado el dolor con la NIPS. Con la información obtenida se creó una base de datos en el programa SPSS. En este programa se realizó el procesamiento y el análisis de la información. Resultados. Se estudiaron 111 neonatos (55 del grupo de estudio y 56 del grupo control). El análisis bivariado mostró una menor puntuación de dolor en el grupo que recibió sucrosa y el modelo de regresión lineal explicó que las variables significativas para la presentación de dolor durante el procedimiento fueron las horas de nacido del neonato y la ausencia de succión no nutritiva, no relacionándose con la aplicación de sucrosa. Conclusión. Los neonatos que recibieron la solución oral de sucrosa antes de la venopunción tuvieron una puntuación media de dolor más baja que el grupo controlado con placebo(AU)
ObjectiveTo evaluate the effectiveness of sucrose use in the prevention of pain during venipuncture in neonates.MethodDouble blind randomized control trial. The population consisted of hospitalized neonates subjected to venipuncture. Sample size was calculated with a 95% confidence level, 80% power, minimum proportion of neonates with pain 40% in the study group and 70% in the control group. The minimum sample size was 49 newborns per group.MethodFive minutes before venipuncture, the neonates received 1cc of oral solution of 12% sucrose (study group) or distilled water (control group). During the procedure the pain level was evaluated with NIPS (Neonatal Infant Pain Scale). A data base was created, and the information processed and analysed using the SPSS program.ResultsA total of 111 neonates were analysed, (55 in study group and 56 in control group). Bivariate analysis showed a smaller NIPS score in the group that received sucrose. Linear regression model explained that the significant variables for pain during the procedure were: hours since birth and the absence of non-nutritious suction, not being related to the sucrose administration.ConclusionNeonates that received the oral solution of sucrose before venipuncture had an average pain score lower than the placebo controlled group(AU)
Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Dor/etiologia , Dor/prevenção & controle , Flebotomia/efeitos adversos , Sacarose/uso terapêutico , Método Duplo-CegoRESUMO
OBJECTIVE: To evaluate the effectiveness of sucrose use in the prevention of pain during venipuncture in neonates. METHOD: Double blind randomized control trial. The population consisted of hospitalized neonates subjected to venipuncture. Sample size was calculated with a 95% confidence level, 80% power, minimum proportion of neonates with pain 40% in the study group and 70% in the control group. The minimum sample size was 49 newborns per group. Five minutes before venipuncture, the neonates received 1cc of oral solution of 12% sucrose (study group) or distilled water (control group). During the procedure the pain level was evaluated with NIPS (Neonatal Infant Pain Scale). A data base was created, and the information processed and analysed using the SPSS program. RESULTS: A total of 111 neonates were analysed, (55 in study group and 56 in control group). Bivariate analysis showed a smaller NIPS score in the group that received sucrose. Linear regression model explained that the significant variables for pain during the procedure were: hours since birth and the absence of non-nutritious suction, not being related to the sucrose administration. CONCLUSION: Neonates that received the oral solution of sucrose before venipuncture had an average pain score lower than the placebo controlled group.
