1.
Org Lett
; 12(19): 4368-71, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20812675
RESUMO
An unprecedented oxidative Prins transformation on phenol derivatives mediated by a hypervalent iodine reagent has been developed. This method allows a rapid access to highly substituted compact systems present in several natural products via a carbon-based addition on an aromatic core. Substitution at each ring position has been demonstrated, enabling synthesis of molecules with up to two contiguous quaternary carbon centers in good yield.
2.
Org Lett
; 11(20): 4756-9, 2009 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19769388
RESUMO
An oxidative Wagner-Meerwein transposition involving different functionalities mediated by a hypervalent iodine reagent has been accomplished. The strategy fits within the concept of "aromatic ring umpolung" and allows rapid access to highly functionalized cores.