RESUMO
STUDY DESIGN: Prospective study. OBJECTIVE: To evaluate the formation of venous gas bubbles following open-sea scuba dives in persons with chronic spinal cord injury (SCI) and in able-bodied diving instructors (C) and to assess the risk for decompression sickness (DCS). SETTING: Field study at the Island of Krk, Croatia. METHODS: Gas bubbles were monitored with an ultrasound scanner 40 min after surfacing. The probability of DCS (P((DCS))) was estimated from the recorded depth-time profile using a decompression model. RESULTS: Divers completed six dives in 3 days using a modified Bühlmann decompression model, and none developed signs of DCS. Mean P((DCS)) was similar in both groups, SCI (0.51+/-0.2%) and C (0.64+/-0.27%), and was seen to increase with subsequent dives. Number of bubbles (bubbles per cm(2)) was low in both groups on all 3 days of diving. CONCLUSIONS: We have used the P((DCS)) as a severity index of diving exposure. Overall, the severity of exposure in SCI subjects was consistent with the range of typical recreational dives, suggesting that the diving profile used is very safe.
Assuntos
Doença da Descompressão/diagnóstico , Mergulho/fisiologia , Exercício Físico/fisiologia , Traumatismos da Medula Espinal/fisiopatologia , Adulto , Gasometria/métodos , Doença Crônica , Croácia , Doença da Descompressão/sangue , Doença da Descompressão/etiologia , Mergulho/efeitos adversos , Embolia Aérea/sangue , Embolia Aérea/diagnóstico , Embolia Aérea/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Monitorização Fisiológica/instrumentação , Monitorização Fisiológica/métodos , Estudos Prospectivos , Medição de Risco/métodos , Traumatismos da Medula Espinal/sangue , Traumatismos da Medula Espinal/reabilitação , Ultrassonografia/métodos , Veias/diagnóstico por imagemAssuntos
Glândulas Salivares/diagnóstico por imagem , Síndrome de Sjogren/patologia , Autoanticorpos/sangue , Biópsia por Agulha Fina , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Sialografia/métodos , Síndrome de Sjogren/diagnóstico por imagem , Síndrome de Sjogren/imunologia , UltrassonografiaRESUMO
Biodistribution studies of radiolabelled [131I]BSA loaded gelatin microspheres were carried out on BALB/c mice after peroral administration. To two groups, the radiolabelled [131I]BSA gelatin microspheres with different mean particle size, 1.196+/-1.961 and 7.028+/-1.231 microm were administered orally. To the control group, a solution of [131I]BSA was also orally administered. Biodistribution was followed periodically within 15 days as a percent of total radioactivity present in stomach, small intestine with Peyer's patches and mesentery, colon with Peyer's patches, appendix and mesentery, liver, spleen, blood, kidney, lungs and heart. The biodistribution data confirmed that uptake in mice into Peyer's patches and passage to the liver and spleen via the mesentery lymph supply and nodes, increased with decreasing particle size.
