RESUMO
Examinations of prenatal fluoride supplemented (PNF) teeth in an animal model and in a five-month human fetus find these teeth to be more developed than the non-supplemented controls. The fact that PNF allows teeth to develop to their full potential suggests that PNF could be an essential nutrient for the entire human and this could be demonstrated most easily during rapid fetal growth. A review of the recent literature, including trials by NIH and The World Health Organization, provide evidence that fluoride (F) does allow the fetus to grow and develop to its full potential. The authors conclude that PNF must be supplied in at least a 2 mg/day pulse dose, and then F must be given from shortly after birth in a daily amount appropriate for the weight of the child with some consideration for the amount of F water utilized.
Assuntos
Desenvolvimento Embrionário e Fetal/efeitos dos fármacos , Fluoretos/uso terapêutico , Ameloblastos/citologia , Animais , Peso Corporal , Estudos de Casos e Controles , Cricetinae , Esmalte Dentário/embriologia , Papila Dentária/embriologia , Suplementos Nutricionais , Modelos Animais de Doenças , Células Epiteliais/citologia , Músculos Faciais/embriologia , Feminino , Fluoretação , Fluoretos/administração & dosagem , Humanos , Incisivo/embriologia , Mandíbula/embriologia , Odontoblastos/citologia , Odontogênese/efeitos dos fármacos , GravidezAssuntos
Clorexidina/análogos & derivados , Cárie Dentária/prevenção & controle , Fluoretos/uso terapêutico , Antissépticos Bucais/efeitos adversos , Intoxicação Alcoólica/etiologia , Criança , Pré-Escolar , Clorexidina/efeitos adversos , Feminino , Humanos , Troca Materno-Fetal , Gravidez , Dente DecíduoRESUMO
This is the case report of a 10 year-old female Caucasian with a mixed dentition Class I right and Class II left side malocclusion and unerupted maxillary central incisors. It was necessary for the oral surgeon to remove twin supernumerary mesiodens prior to the placement of orthodontic appliances. Space was created to accommodate the customary, also unerupted central incisors, which were rotated 90 degrees to the midline.
Assuntos
Incisivo/anormalidades , Dente Supranumerário/complicações , Dente não Erupcionado/etiologia , Criança , Feminino , Humanos , Maxila , Ortodontia Corretiva , Dente Supranumerário/cirurgia , Dente não Erupcionado/terapiaRESUMO
There exists such a wide margin of safety for prenatal fluoride in regard to fluorosis that 2 mg/day can be used as a simplified prenatal fluoride dosage in all areas, regardless of whether they are fluoridated. Any prenatal fluoride dosage between 1 and 4 mg/day is better than no prenatal fluoride at all.
Assuntos
Feto , Fluoretos/administração & dosagem , Efeitos Tardios da Exposição Pré-Natal , Cárie Dentária/prevenção & controle , Feminino , Humanos , GravidezRESUMO
Physico-chemical investigations of enamel from deciduous teeth of a small number of children with and without pre-natal fluoride supplementation (PNF) exhibited the following differences between the PNF and non-PNF enamel, with the former showing: (a) more homogeneous and less extensive patterns of acid-etching; (b) denser crystal populations in intra-prismatic regions; (c) larger prism dimensions; (d) greater total mineral density (wt%ash); (e) higher degree of crystallinity; (f) smaller a-axis dimensions; and (g) more fluoride and less carbonate contents. On the basis of these preliminary findings, further studies with larger numbers of samples would seem appropriate.
Assuntos
Esmalte Dentário/análise , Fluoretos/administração & dosagem , Dente Decíduo/análise , Carbonatos/análise , Fenômenos Químicos , Físico-Química , Criança , Cristalografia , Suscetibilidade à Cárie Dentária , Esmalte Dentário/ultraestrutura , Solubilidade do Esmalte Dentário , Feminino , Fluoretos/análise , Humanos , Troca Materno-Fetal , Microscopia Eletrônica , Minerais/análise , Gravidez , Espectrofotometria Infravermelho , Dente Decíduo/ultraestrutura , Difração de Raios XRESUMO
This article is a report of an in vivo clinical study in which the relationship of sodium fluoride supplementation during pregnancy to the improved occlusal morphology of molar teeth seen in an animal model was determined. Two hundred randomly selected children composed the study population. The mothers of 100 of them had been on the prenatal supplementation (PNF) regimen and 100 whose mothers were not were found to have statistically significant differences in their occlusal molar morphology. Ninety-eight percent of the PNF children have a smooth, naturally sealed appearance to the occlusal surfaces of their primary molars and permanent first molars. The authors conclude that pitted and fissured molars are produced as a result of fluoride deficiency during the secretory phase of crown formation.
Assuntos
Oclusão Dentária , Fluoretos/administração & dosagem , Dente Molar/efeitos dos fármacos , Efeitos Tardios da Exposição Pré-Natal , Criança , Feminino , Humanos , Dente Molar/anatomia & histologia , Gravidez , Calcificação de Dente/efeitos dos fármacos , Dente Decíduo/anatomia & histologia , Dente Decíduo/efeitos dos fármacosRESUMO
Evidence continues to accumulate that the fetal nutritional need for the mineral fluoride begins early in pregnancy and that tablet supplementation is required during the last two trimesters to supply that need, since fluoridated water alone during pregnancy is not sufficient. This study of 492 children confirms the safety and efficacy of using a sodium fluoride tablet supplement, by means of which the obstetrician can help his pregnant patients produce children with superior teeth that are immune to decay.
