1.
Chemistry
; 24(44): 11498-11502, 2018 Aug 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29877598
RESUMO
An operationally simple protocol to affect a radical addition to alkenylboronates that spontaneously undergo a [1,2]-metalate shift is described. Overall, the reaction is a three-component coupling of an organolithium, alkenylboronic ester, and halide which takes place with broad scope and good to excellent yields. Experimental mechanistic investigations support the formation of a boron inverse ylid intermediate.