Silk flow-diverter stent for the treatment of complex intracranial aneurysms: A one-year follow-up multicenter study.

Background Flow-diverter stents have been successfully used in the treatment of complex aneurysms with limited therapeutic alternatives. We report our experience using the Silk flow diverter (SFD; Balt Extrusion, Montmorency, France) for the treatment of complex aneurysms in four Argentine centers. Methods We conducted a retrospective review of 246 consecutive patients who were treated with the SFD at four Argentine centers between January 2009 and January 2017. The patient and aneurysm characteristics, as well as the details of the procedure, were analyzed. The angiographic and clinical findings were recorded during and immediately after the procedure and at 12-month follow-up. Results Angiography follow-up at 12 months was possible in 235 patients (95.5%) with 282 aneurysms. A total of 265 aneurysms (93.9%) presented with complete occlusion of the aneurysmal sac (class 1) and 17 aneurysms (6.1%) presented with partial occlusion (class 2). The 12-month clinical follow-up showed 11 patients with major events (seven, scale 2; five, scale 3; and two, scale 4). The morbidity and mortality rates were 4.2% (11/289) and 2.1% (5/289), respectively. Conclusions The treatment of aneurysms with the SFD was associated with a low rate of complications and a high percentage of aneurysmal occlusion. These findings suggest that SFD is an effective and safe alternative in the endovascular treatment of complex aneurysms.

Disminución del dolor y el peso durante el tratamiento de fisioterapia en pacientes intervenidos de prótesis de rodilla / Decrease in pain and weight loss during physiotherapy treatment in patients operated on for knee prosthesis

El dolor de los pacientes recién intervenidos de prótesis total de rodilla es el principal problema durante la primera fase de fisioterapia, la cual es más rápida y eficiente en pacientes sin sobrepeso. Se realizó un ensayo clínico aleatorio con el fin de demostrar la disminución del dolor y el peso corporal en pacientes obesos intervenidos de prótesis de rodilla mediante la aplicación de un biorritmo fisiológico diario y protocolizado de nutrición, ejercicio físico, hidratación y descanso en los dos meses posteriores a la operación. Al grupo control (19 pacientes) se le aplicó un tratamiento de fisioterapia tras la operación de artroplastia de rodilla, y al grupo de intervención (19 pacientes) además se le aplicó el protocolo. En ambos grupos se efectuaron tres mediciones: recién intervenidos, al mes y a los dos meses. Se observó homogeneidad basal entre ambos grupos en todas las variables recogidas: edad, sexo, índice de masa corporal (IMC), peso y dolor medido mediante escala de valoración analógica (EVA). Se demostraron diferencias significativas en el peso, el IMC y el dolor comparando ambos grupos (p<0,0005). En el grupo de intervención, a los dos meses de la operación los pacientes pesaron 4,5kg menos y el dolor desapareció. En cuanto al grupo control, el peso no varió y el dolor fue de 3 en la EVA. En conclusión, este estudio muestra que un protocolo de ritmo de vida fisiológico de ayuda al tratamiento básico de fisioterapia aplicado en pacientes con sobrepeso recién intervenidos de prótesis de rodilla ocasionaron mejoras significativas en el dolor y la disminución de peso (AU)

Pain of recently operated patients for total knee prosthesis is the main problem during the first phase of physiotherapy, which is faster and more efficient in non-overweight patients. We performed a randomized clinical trial to demonstrate pain and body weight reduction in obese patients undergoing knee prosthesis through daily biorhythms and physiological protocolized nutrition, exercise, hydration and rest during the two months post-operation. The methodology was to compare two groups of 19 patients each. One control group only received physical therapy after knee arthroplasty operation and the protocol was also applied in the second group. Three measurements were performed for each group: at recently intervened, at one month and at two months. Baseline homogeneity was observed between both groups in all of the variables collected: age, sex, body mass index (BMI), weight, measured by pain analogue assessment scale (ASA). Significant differences were demonstrated in weight, BMI and pain when both groups were compared (p<0.0005). At two months of the operation, the interventions weights 4.5kg less and the paid had disappeared. In regards to the control group, their weight did not vary and pain was 3 on the ASA. In conclusion, this study has shown that a physiological life rhythm protocol in combination with basic physiotherapy treatment applied in recently operations overweight patients of knee prosthesis leads to significant improvements in pain and weight loss (AU)

Pseudotumoral chagasic meningoencephalitis as the first manifestation of acquired immunodeficiency syndrome.

BACKGROUND: Patients with AIDS frequently show secondary involvement of the brain by different infectious agents, and Chagas' disease is now recognized as a potential opportunistic infection. To our knowledge, pseudotumoral chagasic meningoencephalitis has not been previously reported as the first manifestation of AIDS. METHODS AND RESULTS: A 30-year-old Argentinian man without any risk factor for HIV infection was admitted to the hospital with an acute onset of drowsiness. A computed tomography scan showed a hypodense parietal tumor-like lesion. Open brain biopsy revealed hemorrhagic necrosis and numerous amastigotes of Trypanosoma cruzi. Nifurtimox was started, but the patient died. CONCLUSIONS: Chagas' disease can reactivate in patients with AIDS and present as a brain mass that is indistinguishable from other infectious or neoplasic processes. Our report demonstrates this entity as the first manifestation of AIDS.

Postpartum bilateral subdural hematomas following spinal anesthesia: case report.

BACKGROUND: Intracranial subdural hematoma is an exceptionally rare complication of spinal anesthesia. We report a case of this infrequent event and consider the influence of cerebral atrophy as a predisposing factor. METHODS AND RESULTS: This 18-year-old woman with severe headaches was admitted to the hospital 42 days after delivery. She had a history of normal pregnancy and uneventful labor and delivery. The epidural anesthesia was satisfactory. Computed tomography showed bilateral chronic subdural hematomas that were surgically removed. An early follow-up scan showed marked resolution of the hematomas and a small sized brain with large subarachnoid space. A late follow-up scan confirmed the diagnosis of brain atrophy. CONCLUSIONS: Persistence of headache and gradual progression despite treatment must be regarded as a sign of intracranial complication following spinal anesthesia. In this case, cerebral atrophy is considered to be a contributory factor for the development of subdural hematoma following dural puncture.

[Atypical algodystrophy of the knee: apropos 2 partial cases]. / Algodistrofia atípica de rodilla: a propósito de dos casos con forma parcial.

Algodystrophy is a common entity which may present in many clinical contexts. Its early diagnosis and therapy are of great prognostic interest. Apart from the typical complete forms there are some other atypical forms, such as partial knee algodystrophy, of difficult diagnosis. Its inclusion in the differential diagnosis of gonalgia occurring in patients attended under many medical specialties is therefore necessary. Two atypical cases of knee algodystrophy in its partial form are reported. One of these cases relapsed at the heterolateral knee after 18 months of the initial presentation; this second episode was also a partial form, a fact which we have not seen reported. The reported cases are here discussed and the scarce literature is reviewed, commenting on the difficulty of the early diagnosis compared with other entities which may mimic the clinical picture, radiological and scanning features of algodystrophy, such as aseptic osteonecrosis or stress fracture. The diagnostic algorithm is discussed, pointing to the usefulness of magnetic resonance (MR) in difficult cases to rule out other entities which would entail different therapeutic modalities.

Special report on reimbursement. HCFA enacts new enforcement remedies covering nursing facilities.

While the regulations are revolutionary in their use of "substantial compliance," the interpretation and application of HCFA's new remedial scheme are still uncertain, as states are given broad discretion in defining important terms and in applying and interpreting the criteria to select remedies. Further complicating the issue is the fact that some states, including California, intend to seek waivers from HCFA to substitute their own state enforcement systems for most, if not all, of the new federal system. Based upon these uncertainties, the enforcement of nursing facility standards will likely be in a state of flux for some time to come.

No long-term solutions in current health care reform proposals.

As this article goes to press, it is nearly impossible to predict what sort of health reform plan will ultimately be passed, if any, and whether any form of long-term care coverage will be included. The need for such coverage will not, however, diminish with the close of the current congressional session and is likely to be a topic of debate for some time. The entire process of health reform legislation has been one of paring down initial hopes and expectations, and it may take many more years, until an even larger segment of our population is aged, before log-term care coverage becomes politically and fiscally desirable enough to withstand the political process.

Lead levels among pregnant women in Hennepin County.

The purpose of this study was to determine the blood lead levels (Pb-B) of urban pregnant women with low incomes and/or living in areas with heavily traveled roads, dilapidated housing, and industrial plants. We measured blood lead in 1,055 pregnant Minneapolis-area women at entry to prenatal care and in one-third of the sample during the second half of pregnancy. The mean Pb-B level of the first sample (n = 1,055) was 1.83 +/- 1.83 micrograms/dL; of the second sample (n = 375), 1.99 +/- 1.92 micrograms/dL. Only one woman had a Pb-B level greater than 12.0 micrograms/dL, which was the result of occupational exposure. The low lead levels found in this study indicate that it is not necessary to routinely screen pregnant women for elevated Pb-B levels in our geographic area. Rather, women should be screened via an environmental questionnaire to ascertain the risk of lead exposure.

Ethnic group differences in nutritional status of young children from low-income areas of an urban county.

A nutrition assessment survey was undertaken among 566 preschool children from randomly selected low income households located within an urban county. The purpose of the survey was to determine the prevalence of selected nutrition problems and to identify relationships among ethnic and economic variables and nutritional status. Underweight was identified in 1.8%, overweight in 15.4%, and short stature in 13.1% of children. Southeast Asian children had a higher prevalence of short stature than the other ethnic groups. Low hemoglobin values were identified in 4.3%, low hematocrit in 6.9%, and elevated erythrocyte protoporphyrin in 6.0% of children. The prevalence of elevated EP was significantly higher among Southeast Asian children than non-Southeast Asians and likely was due to iron deficiency. Results of the survey suggest that Southeast Asian children constitute the group at highest nutritional risk in the low income areas surveyed.

The cost and funding of family practice graduate education in the United States.

This paper reports the findings of a national cost survey of 369 nonmilitary family practice graduate education programs in the United States, 1981-82. The purpose of the study was to develop a reliable revenue and cost information data base to enable an understanding of current family practice education costs and funding. The availability of this information will be of assistance in the development of future budgetary plans for family practice graduate education. The results presented are based on 147 programs associated with hospitals using a non-cost center accounting protocol. These programs provided 100 percent complete revenue and cost data (40 percent of the targeted programs). Major sources of income were hospital support (35 percent), patient income (31 percent), and public dollars (28 percent). The mean cost per accredited position was $57,471. Expenses, each at approximately one third of the total, were resident stipends, faculty salaries, and clinic expenses. Statistically significant differences were found only for source of income when program structure, program size, and geographic location were examined. Recommendations for future family practice funding include modification of present reimbursement formulas and other third-party payment mechanisms, increasing hospital support, maintenance of public subsidies, and development of a uniform system of monitoring and evaluating costs of residency programs operated under both cost center and non-cost center accounting protocols.

Norwalk gastroenteritis: a community outbreak associated with bakery product consumption.

From 23 to 26 August 1982, a gastrointestinal illness occurred among 129 of 248 (52%) persons interviewed who had attended four social events in the Minneapolis-St. Paul area. The median incubation period was 36 hours, and symptoms included diarrhea, nausea, headache, and vomiting. Findings of a food-specific questionnaire given to attendants of the four events confirmed that consumption of cake and frosting was significantly associated with development of the illness (odds ratio, 7.9 to 48.3; p = 0.006 to 0.00001). All cake items were purchased from a single bakery, where the employee who had prepared the frosting had had onset of diarrhea and vomiting on August 20. Given an approximate 60% attack rate among persons who ate frosted items, we estimate that 3000 outbreak-associated cases occurred. Serologic analysis confirmed that 17 of 25 ill persons had fourfold or greater rises in their antibody titer to Norwalk virus. Thus, foodborne transmission of Norwalk virus can result from contamination by a single foodhandler.

Splenomegaly in Hmong refugees.

We review asymptomatic splenomegaly in Indochinese refugees and provide recommendations for evaluation of the problem. Prevalence of splenomegaly in newly arrived Indochinese refugees was 2.5%, three times more prevalent in the Hmong than in the non-Hmong refugees. Male Hmong refugees aged 15 to 29 years had the highest prevalence (10%). For the 50 Hmong refugees studied, there was no evidence that their splenomegaly was caused by clonorchiasis, schistosomiasis, tuberculosis, syphillis, lymphoma, tropical splenomegaly syndrome, or clinical malaria. Cases were more likely to have hepatomegaly, hepatitis B surface antigen positivity, and a low mean corpuscular volume than a reference population of Hmong refugees. Malaria antibody titers were elevated in all but one of the 41 cases (98%) tested.