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1.
Int J Sports Med ; 37(2): 169-74, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26509364

RESUMO

The sports environment is stress-eliciting in that it encapsulates perceived uncontrollability, unpredictability and requires ego-involvement. The HPA axis has been shown (indicated by cortisol release) to respond to anticipated sports competition up to a week prior to the event. Research also alludes to the importance of individual differences, such as optimism and trait perfectionism, in moderating the impact of cortisol upon performance. In total, 41 (male n=27) national (n=38) and international (n=3) swimmers were recruited from northeast England and Australia. Swimmers completed a measure of resilience and also provided buccal saliva swabs, from which total cortisol release prior to and during the event was calculated. Findings revealed that resilience significantly predicted performance and the influence of AUC (cortisol release) upon performance was moderated by resilience. These findings suggest that resilience can influence athletic performance either directly or indirectly, through appraisal (i. e., interpretation of the stressor to be facilitative and non-threatening).


Assuntos
Sistema Hipotálamo-Hipofisário/fisiologia , Sistema Hipófise-Suprarrenal/fisiologia , Estresse Psicológico , Natação/fisiologia , Natação/psicologia , Adolescente , Austrália , Comportamento Competitivo/fisiologia , Inglaterra , Humanos , Hidrocortisona/análise , Masculino , Saliva/química
2.
Genetics ; 158(1): 265-78, 2001 May.
Artigo em Inglês | MEDLINE | ID: mdl-11333235

RESUMO

The N-ethylmaleimide-sensitive fusion protein (NSF) promotes the fusion of secretory vesicles with target membranes in both regulated and constitutive secretion. While it is thought that a single NSF may perform this function in many eukaryotes, previous work has shown that the Drosophila genome contains two distinct NSF genes, dNSF1 and dNSF2, raising the possibility that each plays a specific secretory role. To explore this possibility, we generated mutations in the dNSF2 gene and used these and novel dNSF1 loss-of-function mutations to analyze the temporal and spatial requirements and the degree of functional redundancy between dNSF1 and dNSF2. Results of this analysis indicate that dNSF1 function is required in the nervous system beginning at the adult stage of development and that dNSF2 function is required in mesoderm beginning at the first instar larval stage of development. Additional evidence suggests that dNSF1 and dNSF2 may play redundant roles during embryonic development and in the larval nervous system. Ectopic expression studies demonstrate that the dNSF1 and dNSF2 gene products can functionally substitute for one another. These results indicate that the Drosophila NSF proteins exhibit similar functional properties, but have evolved distinct tissue-specific roles.


Assuntos
Proteínas de Transporte/metabolismo , Drosophila melanogaster/metabolismo , Mesoderma/metabolismo , Sistema Nervoso/metabolismo , Proteínas de Transporte Vesicular , Animais , Animais Geneticamente Modificados , Drosophila melanogaster/embriologia , Feminino , Teste de Complementação Genética , Masculino , Proteínas Sensíveis a N-Etilmaleimida
3.
Percept Mot Skills ; 68(1): 147-56, 1989 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-2928037

RESUMO

The present study was designed to examine how skilled behaviour changes under the effects of two doses of alcohol (0.5 gm/kg and 1 gm/kg). A battery of perceptual-motor reference tests, together with the criterion test of a soccer slalom were given a sample of 48 male volunteers to show how performance strategies changed across the different experimental conditions. Analysis indicated little change between effects of placebo and the lower dose but some change in the composition of performance between placebo and the 1 gm/kg dose. This finding supports further use of factor analysis in the study of skilled behaviour.


Assuntos
Consumo de Bebidas Alcoólicas/psicologia , Desempenho Psicomotor/efeitos dos fármacos , Futebol , Esportes , Adulto , Atenção/efeitos dos fármacos , Relação Dose-Resposta a Droga , Fusão Flicker/efeitos dos fármacos , Humanos , Masculino , Equilíbrio Postural/efeitos dos fármacos , Tempo de Reação/efeitos dos fármacos , Limiar Sensorial/efeitos dos fármacos
4.
Br J Sports Med ; 19(2): 115-8, 1985 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-2862946

RESUMO

The use of benzodiazepines to overcome the possible debilitating effects of travel on football performance is a recent phenomenon and indicative of current usage of such drugs. Contemporary psychological theory is critical of many of the measures used to monitor such drugs. This study has created a battery of tests which include some measures which are deemed more ecologically valid and, for purposes of comparison, some traditional indices. On a sample of First Division professional Association footballers temazepam (40 mg) was compared with placebo on these measures and testing occurred on the afternoon following night time medication. The findings suggest that on such a protocol, perceptual-motor performance is not impaired.


Assuntos
Ansiolíticos/farmacologia , Dopagem Esportivo , Fusão Flicker/efeitos dos fármacos , Destreza Motora/efeitos dos fármacos , Tempo de Reação/efeitos dos fármacos , Futebol , Esportes , Temazepam/farmacologia , Análise de Variância , Humanos , Masculino
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