RESUMO
We report two cases of paroxysmal localized hyperhidrosis (PLH), a rare disorder usually of undetermined origin. The patients were treated with clonidine hydrochloride on the assumption that this paroxysmal phenomenon is of CNS origin, probably hypothalamic. Both patients responded favorably to treatment. In treating PLH, clonidine may serve as an alternative approach to local or surgical treatment.
Assuntos
Clonidina/uso terapêutico , Hiperidrose/tratamento farmacológico , Idoso , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
Neurological complications following rubella are only rarely encountered. However, in many cases severe neurological impairment may occur, leading to permanent disability. In a recent epidemic of rubella in Israel during the years 1978-1979, 20 patients with severe neurological complications have been seen. We report on 5 cases of which 3 are described in detail. Considering the efficacy of immunization against rubella, we suggest that in countries such as England and Israel in which periodic epidemics of rubella occur, a generalized plan of immunization should be undertaken during the first years of life. Such an approach will prevent the neurological complication of congenital, as well as acquired, rubella infection.
Assuntos
Doenças do Sistema Nervoso/etiologia , Rubéola (Sarampo Alemão)/complicações , Adolescente , Adulto , Paralisia Facial/etiologia , Feminino , Hemiplegia/etiologia , Humanos , Masculino , Meningoencefalite/etiologia , Pessoa de Meia-Idade , Hipotonia Muscular/etiologia , Mielite/etiologia , Polirradiculoneuropatia/etiologia , Reflexo Anormal/etiologiaRESUMO
Diurnal and nocturnal sleep records were obtained from a male and a female with Kleine-Levin syndrome, during excessive daytime sleep attacks and while they were asymptomatic. A common pattern of abnormal sleep was seen in both patients even during the asymptomatic period. The female, aflicted with a severe form of periodic hypersomnia, showed nocturnal and diurnal sleep onset REM periods. The different pattern of sleep abnormality in the female could be an expression of the severity of her symptoms or might indicate a variant of sleep abnormality present only in females with Kleine-Levin syndrome.
