RESUMO
Lymphocyte typing for HL-A B27 is useful under conditions in which data based on history and examination are suggestive but not diagnostic of a seronegative spondyloarthropathy. The presence of HL-A B27 would increase the probability of a patient's having one of these entities, but its absence does not rule out such a diagnosis. Furthermore, tissue-typing allows one to predict the probability that a patient with inflammatory bowel disease will develop AS and the likelihood that the family member of a patient with AS will develop a related disease.
Assuntos
Artrite/imunologia , Antígenos HLA/análise , Antígenos de Histocompatibilidade/análise , Articulação Sacroilíaca , Adolescente , Adulto , Artrite/diagnóstico por imagem , Artrite Infecciosa/diagnóstico , Artrite Juvenil/diagnóstico , Artrite Juvenil/imunologia , Artrite Reativa/diagnóstico , Criança , Diagnóstico Diferencial , Feminino , Gonorreia/diagnóstico , Humanos , Técnicas In Vitro , Masculino , Psoríase/complicações , Radiografia , Fatores Sexuais , Espondilite Anquilosante/diagnóstico , Espondilite Anquilosante/diagnóstico por imagem , Espondilite Anquilosante/imunologia , SíndromeRESUMO
Twenty-five grossly obese males were investigated for evidence of osteoarthrosis. A roentgenological survey of multiple joints obtained from 22 of these patients showed few significant degenerative changes. 6 patients (20%) had previously incurred traumatic rents in their menisci necessitating meniscectomy. Our results refute previous claims that obesity is a factor in the genesis of osteoarthrosis but do indicate that obese individuals are more predisposed to traumatic injury of the knee.
