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1.
Artigo em Russo | MEDLINE | ID: mdl-7846882

RESUMO

Thymocyte function and lipid peroxidation in cell membranes of the cerebral cortex and the myocardium of 72 rats were examined to study the stress-limiting mechanism of 10 and 1000 Hz impulse current effect. The additional measurements were as follows: rat and thymus weight, their proportional relations, thymocyte nuclear population, 11--OCS, thyroid hormones (T3, T4), plasma testosterone and insulin, myocardial and cerebral cortical protein. The animals were immobilized for 6 days in individual tight cages where they had food and water. Antioxidant and antistress effects of impulse currents were revealed at definite regimens of their application: 10 Hz stress limiting action was more potent when applied to stressed animals, but 1000 Hz current proved to be an effective prophylactic procedure.


Assuntos
Eletronarcose/métodos , Animais , Antioxidantes , Córtex Cerebral/metabolismo , Fenômenos Químicos , Físico-Química , Eletronarcose/instrumentação , Eletronarcose/estatística & dados numéricos , Peroxidação de Lipídeos , Masculino , Miocárdio/metabolismo , Neurônios/metabolismo , Ratos , Restrição Física , Estresse Psicológico/metabolismo , Estresse Psicológico/terapia
8.
Farmakol Toksikol ; 41(3): 334-8, 1978.
Artigo em Russo | MEDLINE | ID: mdl-658384

RESUMO

By the method of radioactive indication of ashed specimens of the femur, tibia, jaw bones and molars on a model of experimental osteoporosis in rats it is shown that the degree of mineralization of calcified tissues increases under the effect of thyrocalcitonin (TCT). The hypermineralization of jaw bones and, especially, of molars was attended by a lower 45Ca inclusion in these tissues. The structure of the adrenal cortex, kidneys, pancreas and thyroid returned back to normal under the effect of TCT and with carbohydrate rich nutrition, this occurring against the background of a high 45Ca concentration in these organs.


Assuntos
Calcitonina/uso terapêutico , Cálcio/metabolismo , Osteoporose/metabolismo , Animais , Calcinose/metabolismo , Esmalte Dentário/metabolismo , Esmalte Dentário/ultraestrutura , Avaliação Pré-Clínica de Medicamentos , Fêmur/metabolismo , Fíbula/metabolismo , Arcada Osseodentária/metabolismo , Osteoporose/tratamento farmacológico , Ratos , Tíbia/metabolismo , Calcificação de Dente/efeitos dos fármacos
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