RESUMO
The use of osteoplastic materials allows extending indications for dental implants placement by considerable alveolar bone atrophy. The aim of the study was to reveal bone tissue metabolites which can be used as early bone destruction markers after bone augmentation procedure before any radiological signs occur. For this purpose the content of osteocalcinum, C-telopeptides, alkaline phosphatase and lactate dehydrogenase was examined in oral fluid. The increase of osteocalcinum and C-telopeptides and decrease activity of alkaline phosphatase and lactate dehydrogenase in comparison with control represented the pattern specific for bone destruction.
Assuntos
Aumento do Rebordo Alveolar , Regeneração Óssea , Osteogênese , Saliva/metabolismo , Adulto , Fosfatase Alcalina/análise , Fosfatase Alcalina/metabolismo , Colágeno Tipo I/análise , Colágeno Tipo I/metabolismo , Feminino , Humanos , L-Lactato Desidrogenase/análise , L-Lactato Desidrogenase/metabolismo , Masculino , Pessoa de Meia-Idade , Osteocalcina/análise , Osteocalcina/metabolismo , Peptídeos/análise , Peptídeos/metabolismo , Saliva/químicaRESUMO
The paper describes specific correlation of the clinical and molecular pathogenic features in various types of combined periapical lesions. Endodontic apical lesions combined with periodontal disease are characterized by specific radiological signs, shifts in oral fluid physical and chemical properties, the disruption of nitrogen metabolism, increased iron concentration, collagen disruption and impaired concentration ratio of calcium and phosphorous. General depression of immunoglobulin synthesis and increased concentration of cortisol and estradiol in oral fluid are also typical features of combined periapical lesions.
Assuntos
Periodontite Periapical/diagnóstico , Cálcio/análise , Doença Crônica , Diagnóstico Diferencial , Estradiol/análise , Feminino , Humanos , Hidrocortisona/análise , Imunoglobulinas/análise , Imunoglobulinas/biossíntese , Masculino , Periodontite Periapical/diagnóstico por imagem , Periodontite Periapical/metabolismo , Periodonto/imunologia , Periodonto/metabolismo , Fósforo/análise , Radiografia , Saliva/química , Saliva/metabolismoRESUMO
There were disclosed syndrome of minimal thyroid insufficiency in each fourth patient with dental periimplantitis and absence of thyroid gland dysfunction in case of mucositis of periimplantitis origin. The data were presented of minimal thyroid insufficiency manifestations in cases of inflammatory complications of dental implantations the indicator of which was the content of overall and free thyroxin in oral fluid. There were determined common and differentiating peculiarities of oral fluid homeostasis in cases of dental periimplantitis and mucositis of periimplantitis origin.
