Datasets of EQCM-controlled deposition and cycling of thin polypyrrole films in acetonitrile electrolyte solution.

The paper presents three datasets obtained by electrochemical quartz microbalance technique which was applied to studies of conducting polymer film in contact with non-aqueous electrolyte solution. The first dataset describes the calibration procedure of gold-coated quartz crystal, immersed in acetonitrile silver ion-containing electrolyte, by means of silver layer electrodeposition. On the basis of experimentally measured dependence of the resonance frequency on the varying electrode mass in the course of electrochemical silver deposition/dissolution, the calibration coefficient was found to be equal to 13.6 ng/Hz. The second dataset has been collected when thus calibrated EQCM cell was used for determination of the mass change due to the polypyrrole film growth during anodic oxidation of pyrrole monomer from its acetonitrile solution. Its treatment reveals the proportionality between the mass change and the charge spent for pyrrole electrooxidation, the proportionality coefficient being 53.5 g per mole of electrons. The third dataset contains EQCM measurement data during repetitive charge-discharge treatment of the deposited polypyrrole film (cyclic voltammetry, CV) in monomer-free electrolyte. Collected data shows that continuous cycling of the polymer film leads to progressive increase of the cation-exchange contribution to the total ion flux which maintains the film's electroneutrality during variation of its redox state. These findings might be useful both for a qualitative consideration of the cycling stability of polypyrrole in non-aqueous medium and for a quantitative mathematical modelling of polypyrrole electropolymerization and its redox transformations.

[The structure of type 2 diabetes risk-factors in people with normal weight].

In the current study we have presented the analyzed data of screening materials of type 2 diabetes patients aged 45 and above carried out in Kharkov (n=535) and Kharkov district villages (n=1052). It has been established, that the data of cohort people with normal body mass index were practically the same and accounted approximately one fourth of the analyzed patients. At the same time, it appeared that the patients living in the city were more susceptible to metabolic obesity (enlargement of abdominal fat tissue), arterial hypertension, myocardial infarction, insult and heavy family history. Metabolic obesity prevalent in city cohorts practically did not have any effect on the frequency of the above mentioned risk-factors. However, it definitely affected the cardio-vascular component in village cohorts.

[Natural killer cells (CD56, CD16) as a factor of local antitumor immunity in breast cancer].

Two groups of malignancies with significantly distinct ratios of Ki-67 and CD16 expression were identified. Significant direct and inverse correlations between the markers were established (p < 0.01) whereas either group revealed two contradicting patterns of immune response. Whatever hormone receptor, natural killer cells (IKC) (CD16) levels correlated directly with tumor size and lymph node incidence (p < 0.01). IKC (CD56) did not contribute to breast tumor response. Our findings on CD16 expression may be used as criteria in prognosis prediction.

[Comparative evaluation of proliferative activity of breast tumors of different estrogen-progesterone receptor status].

Immunological investigation involving 100 estrogen-progesterone receptor negative (RE-RP-) and 71 estrogen-progesterone receptor positive (RE+RP+) breast cancer patients demonstrated that Ki-67 expression in the former group was twice (49.8%) that in the latter (25.9%). Low Ki-67 expression was found in 39% of RE-RP-tumors whereas high expression--in 28% of RE+RP+ tumors.

[New potential of estrogen and progesterone receptor assay in cytological smears sampled from breast cancer patients]. / Vozmozhnosti opredeleniia retseptorov éstrogenov i progesterona v rake molochnoi zhelezy na tsitologicheskikh mazkakh.

Estrogen (ER) and progesterone (PR) receptors were assayed immunohistochemically in cytological smears and histological samples from 30 breast cancer patients. Since the results reported by the two research centers matched by 73%, it is suggested that running ER and PR determinations on cytological smears in cases of inoperable cancer, preoperative therapy and monitoring may be recommended. Therefore, the 3-4 year old records on ER and PR determinations should be regarded as null and void.

[Immunohistochemical investigation of estrogen and progesterone receptors in breast tumors]. / Immunogistokhimicheskoe issledovanie retseptorov éstrogenov i progesterona v rake molochnoi zhelezy.

Estrogen (ER) and progesterone (PR) receptor levels were assayed in 344 breast tumors. The following 4 patterns were identified: ER+ PR(+)--61%; ER+ PR- 24%; ER- PR(+)--15% and ER- PR(-)--35%. While no correlation was found between histological pattern, on the one hand, and the ER/PR ratio and age, on the other, there was one between estrogen and progesterone receptor content, on the one hand, and age, tumor size and metastatic spread to regional lymph nodes, on the other (p > 0.001).