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1.
Data Brief ; 55: 110691, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-39044912

RESUMO

Precision livestock farming involves the use of new technologies to improve the performance of farms with low profit margins. Since extensive livestock farming is demanding work requiring continuous supervision, it has not improved as drastically as agriculture. Furthermore, nowadays the world is more aware of the importance of respecting biodiversity and reducing the carbon footprint, for which sustainable animal production is recommended. This is the case of small livestock farms, generally located in unpopulated areas and with difficult generational replacement, due to the tasks involved. The use of robots and other devices equipped with intelligent systems can be useful to the farmer in his daily work. In this way, livestock, specifically flocks of sheep, can be monitored and the presence of potential predators such as the wolf identified. Encountering said predator can be avoided by moving the herd to other, safer pasture areas. This work presents a dataset that contains images and videos that allow detecting, classifying and analyzing flocks of sheep and one of their usual predators, wolves. The dataset includes videos of flocks in different locations, with different lighting conditions and different types of sheep. In addition, it contains images of wolves in natural spaces, which are not usually included in the most common datasets used in computer vision. This dataset can be very useful for the work being carried out in extensive precision livestock farming, to develop intelligent systems, such as a robot, that allow autonomous monitoring and control of a herd. Furthermore, it can be used to analyze animal behavior in the presence of a robot, since some of the images have been acquired with the cameras of a quadruped robot. This dataset has been split into three different Zenodo repositories due to its size. Images of sheep can be downloaded from https://zenodo.org/records/11313800 The images of classes 'Person', 'Wolf' and the depth maps for simulation are publicly available at https://zenodo.org/records/11313966 YOLO annotations are at https://zenodo.org/records/11313165.

2.
J Pediatr Endocrinol Metab ; 37(6): 580-584, 2024 Jun 25.
Artigo em Inglês | MEDLINE | ID: mdl-38661069

RESUMO

OBJECTIVES: The most common cause of primary hyperparathyroidism (PPH) in children is a parathyroid adenoma. Among this population, PPH exhibits higher levels of morbidity, severity and target organ involvement compared to adults. When there is suspicion of PPH, cervical ultrasound and 99mTc-sestamibi SPECT/CT are the imaging test traditionally indicated. Among adults, the use of [18F]fluorocholine PET/CT has shown a higher sensitivity than ultrasound and [99mTc]sestamibi SPECT/CT, leading to an expanding adoption in recent years. However, its role in paediatrics has not been clearly defined yet. CASE PRESENTATION: The patient is an adolescent female aged 13 years presented with lithiasis. The analytical study revealed elevated PTH, hipovitaminosis D, hypercalcaemia and hypophosphataemia. Due to the suspicion of PPH, cervical ultrasound and 99mTc-sestamibi SPECT/C were performed, failing to identify hyperfunctioning parathyroid glands. We proceeded to carry out a [18F]fluorocholine PET/CT where a hypermetabolic nodular image was identified, compatible with a hyperfunctioning parathyroid adenoma. The patient underwent surgery, resulting in the normalisation of PTH levels. Pathological anatomy confirmed the presence of a parathyroid adenoma. CONCLUSIONS: In cases where conventional imaging tests yield negative results or discrepancies, we suggest the possibility of the use of [18F]fluorocholine PET/CT for the detection of hyperfunctioning parathyroid adenomas.


Assuntos
Colina , Hiperparatireoidismo Primário , Neoplasias das Paratireoides , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Humanos , Feminino , Adolescente , Hiperparatireoidismo Primário/diagnóstico por imagem , Colina/análogos & derivados , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada/métodos , Neoplasias das Paratireoides/diagnóstico por imagem , Neoplasias das Paratireoides/patologia , Compostos Radiofarmacêuticos , Prognóstico , Adenoma/diagnóstico por imagem , Radioisótopos de Flúor
3.
Am J Trop Med Hyg ; 110(6): 1245-1252, 2024 Jun 05.
Artigo em Inglês | MEDLINE | ID: mdl-38593790

RESUMO

Tick-borne disease burdens are increasing globally, impacting mostly rural and vulnerable communities. Among the most important emerging tick-borne pathogens are the Rickettsia species within the spotted fever group (SFGR) because of their genetic diversity and high lethality rate. Colombia is highly affected by SFGR despite not being reportable diseases; thus, research and clinical management are neglected. Although some departments have demonstrated high seroprevalence rates, in others, such as Boyacá Department, seroprevalence is unknown. Rickettsioses have not been described in Boyacá since 1943, and conversations with local physicians raised suspicions of recent undiagnosed disease compatible with rickettsiosis in some rural areas of the department, warranting epidemiological investigation. Using biobanked human and canine samples from a previous 2021 vector-borne disease study in Miraflores municipality, Boyacá, we had an opportunity to unearth SFGR's exposure in the region. Samples were evaluated using IgG indirect fluorescent assays against SFGR and complemented by survey questionnaires evaluating associated factors. Findings yielded first-time SFGR serological evidence in Boyacá with a 26.5% seroprevalence among dogs and a 20.4% among humans. Human and dog seroprevalences were positively associated, suggesting the presence of domestic transmission. Owning a greater number of domestic animals (prevalence ratio adjusted for all measured factors [aPR], 1.52) and living near crop fields (aPR, 7.77) were associated with an increased likelihood of household seropositivity. Our findings are consistent with the literature in Colombia, uncovering a suspected region where the disease is endemic. Future studies are warranted to continue defining high-risk areas to determine public health intervention plans.


Assuntos
Anticorpos Antibacterianos , Doenças do Cão , Rickettsia , Rickettsiose do Grupo da Febre Maculosa , Cães , Animais , Estudos Soroepidemiológicos , Humanos , Colômbia/epidemiologia , Estudos Transversais , Doenças do Cão/epidemiologia , Doenças do Cão/microbiologia , Masculino , Feminino , Adulto , Anticorpos Antibacterianos/sangue , Rickettsiose do Grupo da Febre Maculosa/epidemiologia , Rickettsiose do Grupo da Febre Maculosa/microbiologia , Pessoa de Meia-Idade , Rickettsia/imunologia , Adolescente , Adulto Jovem , Idoso , Criança , Imunoglobulina G/sangue
4.
Insects ; 15(3)2024 Mar 02.
Artigo em Inglês | MEDLINE | ID: mdl-38535366

RESUMO

Spotted fever group Rickettsia spp. (SFGR) are a large group of tick-borne bacteria causing important emerging and re-emerging diseases that affect animals and humans. While SFGR are found worldwide, a lack of surveillance and misdiagnosis particularly affect South American countries. Colombia is a high burdened country in South America, yet rickettsioses are not deemed a nationally reportable condition limiting disease-specific public health resources. As mortality rates are high for one Rickettsia pathogen species, there is a great need to better understand the epidemiological and ecological factors that increase SFGR transmission risk regionally. This literature review provides an overview of Colombia-based SFGR studies connecting knowledge about both vectors and hosts.

5.
Postgrad Med ; 136(1): 78-83, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38315145

RESUMO

OBJECTIVES: Endoscopic ultrasound-guided tissue acquisition (EUS-TA) has been the most common method used for the preoperative cytopathological diagnosis of solid tumors of the pancreas. There are only a few reported cases about the role of endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) in the pre-operative diagnosis of solid pseudopapillary neoplasms (SPN). This study aimed to evaluate the diagnostic yield of EUS-TA,including endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) andEUS-FNB, in patients with SPN. METHODS: We performed a retrospective analysis of patients with EUS-TA for SPN diagnosis in 2 referral centers. The primary outcome was the diagnostic yield of EUS-TA compared to the surgical specimen. RESULTS: Seventy-four patients with SPN of the pancreas were identified. Eighteen had a EUS-TA (10 EUS-FNB and 8 EUS-FNA). The median age of the patients was 31 years (IQR 21-38), and all patients were women. The most common presenting symptom was abdominal pain. Most of the tumors were in the head of the pancreas (9/18; 50%). The median tumor size by EUS was 4.5 cm (min-max 2-15 cm). The most common appearance on EUS was a solid lesion (n = 8/18, 44.4%). A definitive presurgical cytopathological diagnosis was obtained in 16/18 patients (88.8%) with EUS-TA. The sensitivity and positive predictive value of the EUS-TA were 94% each. One patient in the EUS-FNB group developed mild acute pancreatitis. CONCLUSION: The diagnostic yield of the EUS-TA in SPN is high. In most cases, the diagnosis was obtained with the first procedure. No differences in the diagnostic yield or AEs between EUS-FNA vs. EUS-FNB needles were seen.


Assuntos
Neoplasias Pancreáticas , Pancreatite , Humanos , Feminino , Adulto Jovem , Adulto , Masculino , Neoplasias Pancreáticas/diagnóstico por imagem , Neoplasias Pancreáticas/patologia , Estudos Retrospectivos , Doença Aguda , Pâncreas/diagnóstico por imagem , Pâncreas/patologia
6.
Int J Sports Physiol Perform ; 19(3): 271-279, 2024 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-38167650

RESUMO

PURPOSE: To examine the effects of 4 programming models (linear [LP], undulating [UP], reverse [RP], and constant [CP]) on physical performance. METHODS: Forty-eight moderately strength-trained men were randomly assigned to LP, UP, RP, and CP groups according to their 1-repetition maximum (1RM) in the full-squat exercise (SQ) and followed an 8-week training intervention using the SQ and monitoring movement velocity for every repetition. All groups trained with similar mean relative intensity (65% 1RM), number of repetitions (240), sets (3), and interset recovery (4 min) throughout the training program. Pretraining and posttraining measurements included, in the SQ, 1RM load, the average velocity attained for all absolute loads common to pretests and posttests (AV), and the average velocity for loads that were moved faster (AV > 1) and slower (AV < 1) than 1 m·s-1 at pretraining tests. Moreover, countermovement jump height and 20-m running sprint time were measured. RESULTS: A significant time effect was found for all variables analyzed (P < .05), except for 20-m running sprint time. Significant group × time interactions were observed for 1RM, AV > 1, and AV (P < .05). After training, all groups attained significant strength gains on 1RM, AV, AV > 1, and AV < 1 (P < .001-.01). LP and RP groups improved their countermovement jump height (P < .01), but no significant changes were observed for UP and CP. No significant improvements were achieved in 20-m running sprint time for any groups. CONCLUSIONS: These different programming models are all suitable for improving physical performance. LP and RP induce similar or greater gains in physical performance than UP and CP.


Assuntos
Desempenho Atlético , Treinamento Resistido , Corrida , Masculino , Humanos , Força Muscular , Postura
7.
Trop Med Infect Dis ; 9(1)2024 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-38251211

RESUMO

Chagas disease (CD) remains endemic throughout many regions of Colombia despite implementing decades of vector control strategies in several departments. Some regions have had a significant decrease in vectorial transmission, but the oral ingestion of Trypanosoma cruzi through consumption of contaminated food and drink products is increasingly described. This form of transmission has important public health relevance in Colombia due to an increase in reported acute CD cases and clinical manifestations that often lead to significant morbidity and mortality. Oral CD in Colombia has been associated with the consumption of contaminated fruit juices, such as palm wine, sugar cane, or tangerine juice and water for consumption, or contaminated surfaces where food has been prepared. Another interesting route of oral transmission includes ingestion of unbeknownst infected armadillos' blood, which is related to a traditional medicine practice in Colombia. Some earlier reports have also implemented consumption of infected bush meat as a source, but this is still being debated. Within the Amazon Basin, oral transmission is now considered the principal cause of acute CD in these regions. Furthermore, new cases of acute CD are now being seen in departments where CD has not been documented, and triatomine vectors are not naturally found, thus raising suspicion for oral transmission. The oral CD could also be considered a food-borne zoonosis, and odoriferous didelphid secretions have been implemented in contaminating the human dwelling environment, increasing the risk of consumption of infectious metacyclic trypomastigotes. In this article, we will discuss the complex transmission dynamics of oral CD in Colombia and further examine the unique clinical manifestations of this route of infection. New insights into the oral transmission of Trypanosoma cruzi are being discovered in Colombia, which can help bring increased awareness and a better understanding of this neglected tropical disease to reduce the burden of CD throughout Latin America.

8.
Parasit Vectors ; 17(1): 33, 2024 Jan 25.
Artigo em Inglês | MEDLINE | ID: mdl-38273414

RESUMO

BACKGROUND: Spotted fever group Rickettsia (SFGR) is the largest group of Rickettsia species of clinical and veterinary importance emerging worldwide. Historically, SFGR cases were linked to Rickettsia rickettsii, the causal agent of Rocky Mountain spotted fever; however, recently discovered species Rickettsia parkeri and Rickettsia amblyommatis have been shown to cause a wide range of clinical symptoms. The role of R. amblyommatis in SFGR eco-epidemiology and the possible public health implications remain unknown. METHODS: This study evaluated statewide tick surveillance and land-use classification data to define the eco-epidemiological relationships between R. amblyommatis and R. parkeri among questing and feeding ticks collected across South Carolina between 2021 and 2022. Questing ticks from state parks and feeding ticks from animal shelters were evaluated for R. parkeri and R. amblyommatis using reverse transcriptase quantitative polymerase chain reaction (RT-qPCR) on pooled samples. A Bayesian multivariable logistic regression model for pool testing data was used to assess associations between R. parkeri or R. amblyommatis infection and land-use classification variables among questing ticks. The Spearman correlation was used to evaluate the relationship between the two tested pathogens. RESULTS: The infection prevalence for R. amblyommatis was 24.8% (23.4-26.3%) among questing ticks, and 39.5% (37.4-42.0%) among feeding ticks; conversely, for R. parkeri it was 19.0% (17.6-20.5%) among questing ticks and 22.4% (20.3-24.5%) among feeding ticks. A negative, refractory correlation was found between the species, with ticks significantly more likely to contain one or the other pathogen, but not both simultaneously. The Bayesian analysis revealed that R. amblyommatis infection was positively associated with deciduous, evergreen, and mixed forests, and negatively associated with hay and pasture fields, and emergent herbaceous wetlands. Rickettsia parkeri infection was positively associated with deciduous, mixed, and evergreen forests, herbaceous vegetation, cultivated cropland, woody wetlands, and emergent herbaceous wetlands, and negatively associated with hay and pasture fields. CONCLUSIONS: This is the first study to evaluate the eco-epidemiological factors driving tick pathogenicity in South Carolina. The negative interactions between SFGR species suggest the possible inhibition between the two pathogens tested, which could have important public health implications. Moreover, land-use classification factors revealed environments associated with tick pathogenicity, highlighting the need for tick vector control in these areas.


Assuntos
Ácaros e Carrapatos , Ixodidae , Infecções por Rickettsia , Rickettsia , Carrapatos , Animais , Carrapatos/microbiologia , South Carolina/epidemiologia , Teorema de Bayes , Infecções por Rickettsia/epidemiologia , Infecções por Rickettsia/microbiologia , Ixodidae/microbiologia
9.
Vector Borne Zoonotic Dis ; 24(2): 129-134, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37906122

RESUMO

Background: La Crosse virus is an important endemic public health concern in the North Carolina Appalachian Mountains; however, human incidence is not commonly noted in this region on the South Carolina side of the mountain range border. No relevant studies have been performed in South Carolina evaluating mosquito vector populations for La Crosse virus (LACV) infection; thus, a pilot mosquito surveillance study was executed in summer 2020. Material and Methods: Vector surveillance occurred at five South Carolina state parks bordering neighboring state endemic counties from May to August 2020. Collections were approved by the state park authority, as noted in Permit No. N-8-20. Results: All three competent mosquito vectors were collected during the study duration; however, these vectors were collected in low abundance: Aedes triseriatus (4.5% of all collected mosquitos); Aedes albopictus (2.0%); Aedes japonicus (1.4%). Principal mosquito vector specimens, Ae. triseriatus, were sent to Centers for Disease Control and Prevention for testing of LACV by real-time reverse transcription PCR-all were negative. Discussion: While entomologic evidence suggests low transmission risk for this arbovirus in the South Carolina Appalachian Mountain region, further eco-epidemiologic investigations are warranted to understand this endemicity variance within a relatively small geographic area.


Assuntos
Aedes , Vírus La Crosse , Animais , Humanos , South Carolina/epidemiologia
10.
Ticks Tick Borne Dis ; 15(2): 102288, 2024 03.
Artigo em Inglês | MEDLINE | ID: mdl-38071922

RESUMO

Illness caused by spotted fever group Rickettsia (SFGR) is increasing nationally, with affluent, white residents most likely to be diagnosed. The common under-representativeness of marginalized populations in research studies and these vulnerable populations' health inequities make veritable epidemiologic risk factor profiling challenging, which inhibits equitable public health intervention. The current study leveraged 749 banked sera and associated surveys from a cross-sectional minority-represented COVID-19 study to perform an SFGR seroprevalence investigation. SFGR titers (1:64, 1:128, 1:256, 1:512, and 1:1024) were measured using commercially available indirect fluorescent antibody slides-SFGR positive cases were defined as titers ≥1:128. Multivariable logistic regression and Getis-Ord-Gi* hotspot analyses were used to identify seropositivity-associated factors and determine seropositive clusters. Among a mostly minority and lower socioeconomic population, a 3.4 % SFGR seropositivity was noted at the ≥1:128 titer level. Male gender (Odds Ratio (OR): 3.20; adjusted Odds Ratio (aOR)s: 3.73), age (aOR: 1.05), any frequency of tick bite (OR: 2.29), and spending time working outdoors (OR: 5.05) were associated with SFGR IgG seropositivity. Moreover, the geospatial analysis showed clusters of seropositivity in areas where previous case reports occurred, suggesting potential endemic foci.


Assuntos
Rickettsia , Rickettsiose do Grupo da Febre Maculosa , Humanos , Masculino , Animais , South Carolina , Estudos Soroepidemiológicos , Estudos Transversais , Fatores Epidemiológicos , Rickettsiose do Grupo da Febre Maculosa/microbiologia
11.
Int J Surg Pathol ; : 10668969231195074, 2023 Sep 18.
Artigo em Inglês | MEDLINE | ID: mdl-37722867

RESUMO

We present the case of a 6-year-old girl who presented with alterations in the voiding stream. On physical examination, a very small urethral meatus was identified at the expense of a membrane. The renovesical ultrasound showed no alterations. An uroflowmetric study was performed, showing a bladder outlet obstruction pattern. The urethral meatus was calibrated and a ventral meatotomy was performed. The histological study of the resected membrane showed a transitional urethral mucosa with chronic focal inflammation and discrete hyperplasia. The patient evolved favorably, with resolution of the symptoms and no notable complications. This is, to the best of our knowledge, the first reported case with a histological study of a congenital meatal urethral stenosis. In the presence of lower urinary tract obstruction, this entity should be considered in the differential diagnosis. Surgical treatment is curative.

12.
J Med Entomol ; 60(6): 1398-1405, 2023 11 14.
Artigo em Inglês | MEDLINE | ID: mdl-37658780

RESUMO

The first established population of the Asian longhorned tick Haemaphysalis longicornis (Neumann, Acari: Ixodidae) was discovered in a northern South Carolina county in June 2022. A coordinated investigation was launched to investigate the invasive tick's pathogen infection prevalence and blood meal preferences. Almost 2,000 Ha. longicornis ticks were collected from one cattle field. A majority of collected ticks had evidence of cattle and dog blood meals, and multiple samples were tested positive for Borrelia burgdorferi s.l. and Theileria orientalis-first reports for these pathogens in this tick species in South Carolina. This investigation was the direct result of a collaborative education campaign and tick surveillance program launched earlier in the year with multiple state partners.


Assuntos
Ixodidae , Theileria , Carrapatos , Bovinos , Animais , Cães , Prevalência , South Carolina
14.
JMIR Public Health Surveill ; 9: e34579, 2023 04 19.
Artigo em Inglês | MEDLINE | ID: mdl-36720159

RESUMO

BACKGROUND: The COVID-19 pandemic has challenged public health efforts globally. Timely population-based surveillance is crucial to support public health programs and policies to limit the spread of COVID-19. The South Carolina (SC) Sampling and Testing Representative Outreach for Novel Coronavirus Guidance (SC STRONG) statewide initiative was established to estimate population-level prevalence and immunity and characterize the transmission dynamics of SARS-CoV-2 using community testing and online surveys. OBJECTIVE: This paper aimed to leverage the survey data collected as part of the initiative to understand risk perceptions, testing practices, and preventive behaviors and identify risk factors for COVID-19 test positivity in SC over time. METHODS: Probability proportionate to size cluster random sampling was used to select SC residents to participate in testing for COVID-19 infection and antibodies and to complete an online survey. This paper focuses on data from the online surveys completed between November 2020 and June 2021. Descriptive statistics were used to describe risk perceptions, attitudes and behaviors, and associated changes over time. Univariate and multivariate logistic regression models were used to identify factors associated with self-reported COVID-19 test positivity. RESULTS: Among the 7170 online survey respondents, 58.7% (4213/7170) self-reported ever testing for COVID-19. The most commonly cited barriers to testing were inconvenient dates, time, and location, as well as discomfort. Overall, 18.7% (790/7170) of respondents reported a history of COVID-19 test positivity. Multivariate logistic regression results indicated that individuals who were aged 50 years or older, self-identified as Black/African American, were obese, and were employed as frontline health care workers or nursing home staff were more likely to self-report COVID-19 test positivity. By contrast, there was a decreased likelihood of test positivity among respondents who were concerned about the burden of COVID-19 in their community and about being infected. CONCLUSIONS: Strategies to remove testing barriers should be implemented to improve access. Our findings provide insights on statewide testing patterns, adoption of prevention behaviors, and risk factors for infection and may inform public health strategies to curb transmission.


Assuntos
Teste para COVID-19 , COVID-19 , Conhecimentos, Atitudes e Prática em Saúde , Pandemias , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , COVID-19/diagnóstico , COVID-19/epidemiologia , COVID-19/prevenção & controle , COVID-19/psicologia , Teste para COVID-19/estatística & dados numéricos , Pandemias/prevenção & controle , Fatores de Risco , SARS-CoV-2/isolamento & purificação , Autorrelato/estatística & dados numéricos , South Carolina/epidemiologia , Inquéritos e Questionários , Medição de Risco
15.
Eur J Sport Sci ; 23(3): 381-392, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35109780

RESUMO

ABSTRACTThe present study investigates the effect of an acute intake of caffeine on the diurnal variation of neuromuscular performance in resistance-trained women. A total of 15 resistance-trained women participated in the current triple-blind, placebo-controlled, crossover experimental study. We assessed neuromuscular performance (i.e. ballistic (countermovement jump [CMJ] height and bench press throw [BPT] peak velocity), maximal strength (squat and bench press [BP] one-repetition maximum [1RM]), and strength-endurance [average velocity of the set during squat and number of repetitions-to-failure in BP]) four times at within 7 days. The participants ingested an acute dose of caffeine (3 mg/kg) or a placebo at 9-11 am and/or 17-19 pm. CMJ height (P = .016) and BP peak velocity (P = .012) were higher in the afternoon than in the morning. Compared to placebo, caffeine intake increased CMJ height by 3.1% in the morning and 1.6% in the afternoon (P = .035), but it had no effect on BPT peak velocity (P = .381). Maximal strength and strength-endurance performances were not affected by the time-of-day or caffeine intake (all P > .3). No significant interaction (time-of-day x substance) was observed in any of the above-mentioned outcomes (all P > .1). In conclusion, an acute dose of caffeine in the morning was effective to restore CMJ performance to levels found in the afternoon, while this effect was not observed neither in BPTpeak velocity nor in lower- and upper-body maximal strength and strength-endurance performance. Moreover, lower- and upper-body ballistic performance were greater in the afternoon than in the morning in resistance-trained women, while the acute intake of caffeine was only effective to increase CMJ height.HighlightsBallistic performance is probably higher in the afternoon than in the morning in resistance-trained women.An acute intake of caffeine is effective to increase countermovement jump performance.The ingestion of an acute dose of caffeine in the morning restored countermovement jump performance to levels found in the afternoon.


Assuntos
Cafeína , Ritmo Circadiano , Feminino , Humanos , Cafeína/farmacologia , Ingestão de Alimentos , Terapia por Exercício , Estado Nutricional , Estudos Cross-Over
16.
Eur J Sport Sci ; 23(6): 936-942, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35437101

RESUMO

Maximal fat oxidation during exercise (MFO) and the intensity that elicits MFO (Fatmax) seems to show a diurnal variation in men, which favours an increased performance in the afternoon than the morning. At present, it remains unknown whether the observed MFO and Fatmax diurnal variation in men is also present in women. Therefore, the current study examined the diurnal variations of MFO and Fatmax in women. Nineteen healthy women (age: 26.9 ± 8.7 years, maximum oxygen uptake: 39.8 ± 6.5 ml/kg/min) participated in the study. MFO and Fatmax were determined by a graded exercise test in cycloergometer using a cross-over design performed on two separate daytime schedules, one conducted in the morning (8am-11am) and one in the afternoon (5pm-8pm). Stoichiometric equations were used to calculate fat oxidation rates. There were no significant differences between MFO-morning and MFO-afternoon (0.24 ± 0.10 vs. 0.23 ± 0.07 g/min, respectively; P = 0.681). Similarly, there was no significant differences between Fatmax-morning and Fatmax-afternoon (41.1 ± 4.7 vs. 42.6 ± 5.5% of maximal oxygen uptake, respectively; P = 0.305). These results persisted after controlling for fat mass percentage (all P > 0.5). In summary, the main finding of the present study was that MFO and Fatmax were similar independent of the time-of-day when the exercise test is performed in healthy women. These results have important clinical implications since they suggest that, in contrast to what was found in men, MFO and Fatmax show similar rates during the course of the day in women.HighlightsMFO and Fatmax were similar during the afternoon and morning in young healthy women.Our results suggest that, in women, it does not matter when endurance exercise is performed in term of fat metabolism during exercise.


Assuntos
Tecido Adiposo , Consumo de Oxigênio , Masculino , Humanos , Feminino , Adolescente , Adulto Jovem , Adulto , Estudos Cross-Over , Tecido Adiposo/metabolismo , Calorimetria Indireta , Oxigênio/metabolismo , Oxirredução , Teste de Esforço
17.
Zoonoses Public Health ; 70(1): 103-110, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-36177916

RESUMO

Animal rabies cases have increased steadily in South Carolina (SC) for the past decade. An understanding of the population's awareness and understanding of the disease is needed to tailor public health interventions. A marketing list-serv of SC residents' email addresses was used to recruit anonymous respondents for a Knowledge Attitudes and Practices (KAP) electronic survey. A total 516 South Carolinians completed the 31-question survey. Quantile regression and a Pearson's correlation evaluated potential associations between respondent's rabies knowledge and their attitudes and practices. Knowledge was assessed on topics of rabies biology, state animal case counts and rabies pet-related laws. Level of concern and level of knowledge were positively correlated. Additionally, statewide hotspot analysis revealed geographic areas warranting targeted public health interventions; counties with low public concern juxtapositioned with high animal rabies case counts. This study demonstrates the utility of statewide KAPs to gauge populations rabies perception and related preventative actions to tailor appropriate educational programs to limit human-animal rabies exposures.


Assuntos
Mordeduras e Picadas , Doenças do Cão , Raiva , Cães , Humanos , Animais , Raiva/epidemiologia , Raiva/prevenção & controle , Raiva/veterinária , Estudos Transversais , South Carolina/epidemiologia , Mordeduras e Picadas/veterinária , Conhecimentos, Atitudes e Prática em Saúde , Inquéritos e Questionários
18.
Int J Surg Pathol ; 31(5): 680-688, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35946082

RESUMO

Congenital prepubic sinus (PS) is an extremely infrequent malformation consisting of a prepubic fistulous tract that classically does not communicate with the genitourinary system. Previous studies centered on its immunohistochemical characterization have shown inconsistent results, and the etiology has not been clarified. We present the case of a 2-year-old male who presented since birth with a fistulous orifice on the dorsum of the penis. He had no associated symptoms. Under general anesthesia, the fistulous tract was explored, and methylene blue was instilled through it. After cystoscopically verifying the absence of communication with the urethra, a complete resection of the lesion was performed. The immunohistochemical study showed positivity for low and high molecular weight keratins and a transitional pattern for keratin 7 and GATA3, with positivity at cul de sac level and negativity at proximal level. These findings suggest that this lesion is an incomplete dorsal duplication variant.


Assuntos
Pênis , Uretra , Masculino , Humanos , Pré-Escolar , Uretra/cirurgia , Uretra/patologia , Pênis/patologia , Pelve , Queratinas , Queratina-7
19.
An. sist. sanit. Navar ; 45(3): e1026, Sep-Dec. 2022. ilus
Artigo em Espanhol | IBECS | ID: ibc-219070

RESUMO

Dentro de las causas de abdomen agudo quirúrgico, la infección de un remanente uracal puede pasar desapercibida en cuadros evolucionados a pesar de las pruebas complemetarias habituales.Presentamos tres casos de varones de 11, 6 y 4 años llevados a urgencias por dolor en fosa iliaca derecha, fiebre y síntomas urinarios. La exploración y las pruebas complementarias eran compatibles con patología apendicular aguda evolucionada y fueron intervenidos con dicha sospecha. En el quirófano se descartó apendicitis y se documentaron cambios inflamatorios sugestivos de infección de remanente uracal. Las complicaciones de los remanentes uracales deben ser tenidas en cuenta en el diagnóstico diferencial del abdomen agudo quirúrgico, ya que la infección evolucionada de estos puede confundirnos. Un diagnóstico de presunción más certero puede cambiar nuestra actitud terapéutica, quirúrgica y el seguimiento.(AU)


Among the causes of acute surgical abdomen, infection of a urachal remnant may go unnoticed despite routine complementary studies.We present three cases in boys aged 11, 6, and 4 years who were brought to the emergency department for right iliac fossa pain, fever, and urinary symptoms. Examination and complementary tests results were compatible with acute complicated appendicitis and were sent to surgery. While in the operating room, appendicitis was excluded and inflammatory changes suggestive of infection of the urachal remnant were documented. Complications of urachal remnants should be considered in the differential diagnosis of acute surgical abdomen, since advanced infection of the urachus may be a cause of confusion. A more accurate presumptive diagnosis can change the therapeutic/surgical approach and follow-up.(AU)


Assuntos
Humanos , Masculino , Criança , Dor Abdominal , Apendicite , Úraco , Pacientes Internados , Exame Físico , Pediatria , Dor Aguda
20.
An Sist Sanit Navar ; 45(3)2022 Dec 28.
Artigo em Espanhol | MEDLINE | ID: mdl-36576388

RESUMO

Among the causes of acute surgical abdomen, infection of a urachal remnant may go unnoticed despite routine complementary studies. We present three cases in boys aged 11, 6, and 4 years who were brought to the emergency department for right iliac fossa pain, fever, and urinary symptoms. Examination and complementary tests results were compatible with acute complicated appendicitis and were sent to surgery. While in the operating room, appendicitis was excluded and inflammatory changes suggestive of infection of the urachal remnant were documented. Complications of urachal remnants should be considered in the differential diagnosis of acute surgical abdomen, since advanced infection of the urachus may be a cause of confusion. A more accurate presumptive diagnosis can change the therapeutic/surgical approach and follow-up.


Assuntos
Abdome Agudo , Apendicite , Cisto do Úraco , Úraco , Masculino , Humanos , Abdome Agudo/diagnóstico , Abdome Agudo/etiologia , Cisto do Úraco/complicações , Cisto do Úraco/diagnóstico , Cisto do Úraco/cirurgia , Apendicite/diagnóstico , Apendicite/cirurgia , Apendicite/complicações , Úraco/cirurgia , Diagnóstico Diferencial
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