RESUMO
La instilación intravesical de bacilo de Calmette-Guérin (BCG) es un procedimiento ampliamente utilizado y eficaz para el tratamiento del carcinoma vesical superficial de grado intermedio y alto. La aparición de efectos colaterales osteoarticulares es infrecuente comparado con el número de dosis administradas, y dentro de estos se incluye la artritis reactiva. Presentamos el caso de un paciente varón de 54 años, HLA B27 (+), que desarrolló un cuadro de artritis reactiva caracterizado por oligoartritis asimétrica y dactilitis tras la segunda instilación intravesical de BCG, y que se resolvió con el tratamiento con etoricoxib e isoniazida (AU)
The intravesical instilation of bacillus Calmette-Guérin (BCG) is a widely used and efficacious procedure for treatment of intermediate to high-grade superficial bladder cancer. The occurrence of osteoarticular side effects is infrequent compared to the number of administrated doses, and reactive arthritis is included within these effects. We present the case of a 54 years old HLA-27 (+) male, who developed reactive arthritis featuring asymmetric olygoarthritis and dactylitis after the second intravesical BCG instillation, which was resolved with administration of Etoricoxib and Isoniazid (AU)
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Artrite Reativa/diagnóstico , Artrite Reativa/tratamento farmacológico , Administração Intravesical , Instilação de Medicamentos , Mycobacterium bovis , Mycobacterium bovis/isolamento & purificação , Antígeno HLA-B27 , Antígeno HLA-B27 , Imunoterapia/métodos , Artrite Reativa/fisiopatologia , Doenças Reumáticas/complicações , Doenças Reumáticas/diagnóstico , Doenças Reumáticas/tratamento farmacológico , Imunoterapia/tendências , ImunoterapiaRESUMO
The intravesical instilation of bacillus Calmette-Guérin (BCG) is a widely used and efficacious procedure for treatment of intermediate to high-grade superficial bladder cancer. The occurrence of osteoarticular side effects is infrequent compared to the number of administrated doses, and reactive arthritis is included within these effects. We present the case of a 54 years old HLA-27 (+) male, who developed reactive arthritis featuring asymmetric olygoarthritis and dactylitis after the second intravesical BCG instillation, which was resolved with administration of Etoricoxib and Isoniazid.
