RESUMO
Objetivo Comparar la evidencia de los diferentes tratamientos para el linfedema y los posibles dolores miofasciales postmastectomía, para conseguir la máxima calidad de vida de los pacientes. Estrategia de búsqueda y selección de estudios Se realizó una búsqueda en las bases de datos PubMed, Phisiotherapy Evidence Database (PEDro) y Web of Science (WOS) durante marzo y abril del año 2022. Se tuvo en cuenta que los pacientes hubiesen sido intervenidos quirúrgicamente por cáncer de mama (CaMama), mayores de 18 años y que los estudios fuesen ensayos clínicos; resultando un total de 10 artículos seleccionados. Se evaluó la calidad metodológica y factor de impacto de cada uno de ellos. Síntesis de resultados Las variables analizadas fueron reducción del linfedema, calidad de vida y abordaje del dolor. El tratamiento a través de drenaje linfático manual (DLM) presentó mejorías en todos los artículos que hacían referencia a la reducción del linfedema, tanto de forma individual como de forma aislada; en cambio, respecto a los dolores miofasciales el tratamiento de liberación miofascial mostró mejoras tanto en la calidad emocional como en la disminución del dolor, siendo más efectivo en esta última variable. Conclusiones Los tratamientos que mejoran la calidad de vida y dolor de los pacientes que han sufrido una intervención quirúrgica debido al CaMama, además de reducir el linfedema son DLM, facilitación neuromuscular propioceptiva (FNP), liberación miofascial y programas de ejercicios y entrenamientos. La limitación principal respecto a los tratamientos, es que no existe ningún programa de intervención específico (AU)
Objective To compare the evidence of the different treatments for lymphedema and possible postmastectomy myofascial pain, to achieve the highest quality of life for patients. Search strategy and selection of studies A search was carried out in the PubMed, Physiotherapy Evidence Database (PEDro) and Web of Science (WOS) databases during March and April 2022. It was taken into account that the patients had undergone surgery surgically for breast cancer, that they were over 18 years of age and that the studies were clinical trials; resulting in a total of 10 selected articles. The methodological quality and impact factor of each of them were evaluated. Summary of results The variables analyzed were reduction of lymphedema, quality of life and pain management. Treatment through manual lymphatic drainage (MLD) presented improvements in all the articles that made reference to the reduction of lymphedema, both individually and in isolation; On the other hand, regarding myofascial pain, myofascial release treatment showed improvements in both emotional quality and pain reduction, being more effective in this last variable. Conclusions The treatments that improve the quality of life and pain of patients who have undergone surgery due to breast cancer, in addition to reducing lymphedema, are manual lymphatic drainage, proprioceptive neuromuscular facilitation, myofascial release, and exercise and training programs. The main limitation regarding treatments is that there is no specific intervention program (AU)
Assuntos
Humanos , Feminino , Drenagem Linfática Manual , Linfedema Relacionado a Câncer de Mama/terapia , Qualidade de Vida , Neoplasias da Mama/cirurgia , MastectomiaRESUMO
Bone Regeneration represents a clinical need, related to bone defects such as congenital anomalies, trauma with bone loss, and/or some pathologies such as cysts or tumors This is why a polymeric biomaterial that mimics the osteogenic composition and structure represents a high potential to face this problem. The method of obtaining these materials was first to prepare a stabilized hydrogel by means of physical bonds and then to make use of the lyophilization technique to obtain the 3D porous scaffolds with temperature conditions of -58 °C and pressure of 1 Pa for 16 h. The physicochemical and bioactive properties of the scaffolds were studied. FTIR and TGA results confirm the presence of the initial components in the 3d matrix of the scaffold. The scaffolds exhibited a morphology with pore size and interconnectivity that promote good cell viability. Together, the cell viability and proliferation test, Alamar BlueTM and the differentiation test: alizarin staining, showed the ability of physically stabilized scaffolds to proliferate and differentiate swine dental pulp stem cell (DPSCs) followed by mineralization. Therefore, the Cs-PCL-PVA-HA scaffold stabilized by physical bonds has characteristics that suggest great utility for future complementary in vitro tests and in vivo studies on bone defects. Likewise, this biomaterial was enhanced with the addition of HA, providing a scaffold with osteoconductive properties necessary for good regeneration of bone tissue. Graphical abstract.
