Colitis pseudomembranosa tras abdominoplastia circunferencial postbariátrica. Caso clínico / Pseudomembranous colitis after post-bariatric circumferential abdominoplasty. Case report

Los pacientes que se someten a cirugía reconstructiva del contorno corporal tras pérdida masiva de peso secundaria a cirugía bariátrica, presentan cambios importantes en la microbiota intestinal, sus propiedades antimicrobianas y en la absorción de nutrientes. Estas alteraciones, sumadas al uso de antibióticos profilácticos para cirugía y agentes reductores de la motilidad intestinal, los vuelven susceptibles a infecciones nosocomiales por oportunistas como el Clostridium difficile, que tiene una presentación clínica que varía desde las formas leves hasta la colitis fulminante. Presentamos el caso de una paciente con pérdida masiva de peso posterior a un bypass gástrico, a quien se le realizó abdominoplastia circunferencial en flor de lis y que en el postoperatorio mediato presentó colitis pseudomembranosa tras autorrecetarse loperamida y que a pesar de los tratamientos agresivos utilizados, requirió abordaje quirúrgico con colectomía subtotal por el desarrollo de megacolon tóxico. Finalmente se logró resolver el cuadro séptico pero con secuelas gastrointestinales inherentes a una resección intestinal y disminución de la calidad de vida. Es de suma importancia la educación de los pacientes con pérdida masiva de peso respecto a las posibles complicaciones de la cirugía reconstructiva y los medicamentos utilizados, así como de su apego al tratamiento indicado por su médico (AU)

Patients undergoing reconstructive surgery of body contour after massive weight loss due to bariatric surgery, suffer important changes in the intestinal microbiota, its antimicrobial properties and the nutrient absorption capacity. These abnormalities, plus the utilization of prophylactic antibiotics for surgery and intestinal motility reducing agents, make patients vulnerable to nosocomial infections by opportunists such as Clostridium difficile, which has a clinical presentation that oscillates from mild to fulminant colitis. We present a case of a patient with massive weight loss after a bypass surgery who underwent circumferential abdominoplasty in fleur de lis and presented pseudomembranous colitis in the postoperative period after self-administration of loperamide. Despite aggressive treatments, the patient required surgery with subtotal colectomy due to the development of toxic megacolon. Finally, she managed to overcome sepsis, however with gastrointestinal sequels that diminish quality of life. It is extremely important to educate patients with massive weight loss about possible complications of reconstructive surgery and medications used, as well as their adherence to prescriptions made by the treating physician (AU)

Idiopathic granulomatous mastitis. Experience at a cancer center.

BACKGROUND: Idiopathic granulomatous mastitis (IGM) is a benign breast disease that has been described as a rare granulomatous inflammation (GI). It can mimic inflammatory breast cancer. MATERIAL AND METHODS: We included women with a diagnosis of IGM referred to an oncologic hospital between January 01, 2007 and to March 31, 2011, with diagnosis of breast cancer, in whom biopsy reported GI, without other cause related. The aim of this study was to review the clinical, radiologic and pathologic characteristics of a cohort of women with IGM. RESULTS: We analyzed 58 patients; mean age was 38 ± 12 years. Mammography showed diffuse asymmetry (n = 19) and focal asymmetry (n = 13); breast ultrasound showed heterogeneous and hypoechoic areas (n = 28) and lumps (n = 21) as the most frequent lesions. All biopsies showed lobulocentric GI. Treatment included antibiotics (n = 20), steroids (n = 8), both treatments (n = 20), surgical excision (n = 3) and observation (n = 7). Forty-three patients (74%) had complete remission; mean time to remission was 9.5 ± 5.8 months. Fifteen (26%) had partial remission. Any patient had progression or relapse. CONCLUSIONS: IGM is a benign breast condition that may mimic breast inflammatory cancer. Ultrasonography and mammography findings reveal characteristic data that can be useful for establishing the diagnosis; however, biopsy is the gold standard for its diagnosis and should be taken in any patient even with a mild suspicion of cancer.