Comparación del estado nutricional de estudiantesuniversitarios wixaritári y mestizos: indicadoresantropométricos y vulnerabilidad social / Comparison of the nutritional status of university students from wixaritáriand mestizos: anthropometric indicators and social vulnerability

Objetivo: Describir y comparar el estado nutricional de estudiantes universitarios wixaritári y mestizos a través de indicadores antropométricos. Métodos: Estudio descriptivo transversal. A cada estudiante se le tomaron las mediciones antropométricas de peso, talla, circunferencia media de brazo, de cadera, cintura, diámetro humeral, pliegue cutáneo bicipital, tricipital, subescapular y suprailíaco, se obtuvieron los índices antropométricos: índice de masa corporal, índice cintura cadera, riesgo cardiovascular por ICC, porcentaje de grasa corporal y complexión. Resultados: Existió una muestra de 388 estudiantes universitarios, de los cuales 46 son alumnos que pertenecen a la etnia wixárika y 342 son mestizos. Se presentó una diferencia estadísticamente significativa (p ≤0,05) en talla, circunferencia de cadera, PCT, PCB, PCSI y PCSE, el IMC y la distribución de grasa. Un porcentaje del 45%(154) de los estudiantes mestizos presento malnutrición y comparado con solo un 17.7%(8) de los estudiantes wixaritári, siendo el sobrepeso el problema con mayor prevalencia en ambos grupos. En cuanto a la complexión, un 76.8%(298) es la media de complexión pequeña, un 21.6% (84) la media de complexión mediana y un 1.8% (6) la media de complexión grande de toda la muestra. En cuanto a la distribución de grasa, un porcentaje más alto de alumnos wixaritári presentan distribución androide. Conclusiones: Es necesaria la creación de políticas públicas institucionales que consideren las necesidades de sus grupos específicos, de manera que se pueda construir un ambiente que fortalezca la dimensión identitaria de sus grupos, garantizando la preservación de sus valores y tradiciones de la cultura, asegurando espacios y alimentos que sean apropiados.(AU)

Objective: Describe and compare the nutritional status ofwixaritari and mestizo university students through anthropometric indicators. Methods: Descriptive cross-sectional study. Anthropometricmeasurements of weight, height, average arm circumference,hip, waist, humeral diameter, bicipital, tricipital, subscapular andsuprailiac skin fold were taken for each student, anthropometricindices were obtained: body mass index, waist index hip, cardiovascular risk due to CHF, body fat percentage and complexion. Results: There was a sample of 388 university students, ofwhich 46 are students belonging to the Wixárika ethnic groupand 342 are mestizos. There was a statistically significant difference (p ≤ 0.05) in size, hip circumference, PCT, PCB, PCSIand PCSE, BMI and fat distribution. A percentage of 45%(154) of the mestizo students presented malnutrition andcompared with only 17.7% (8) of the wixaritári students, being the overweight the most prevalent problem in bothgroups. As for the complexion, 76.8% (298) is the average ofsmall complexion, 21.6% (84) the average of medium complexion and 1.8% (6) the average of large complexion of theentire sample. Regarding fat distribution, a higher percentageof wixaritári students have an android distribution. Conclusions: The creation of institutional public policiesthat consider the needs of their specific groups is necessary,so that an environment that strengthens the identity dimension of their groups can be built, guaranteeing the preservation of their values and traditions of culture, ensuring spacesand food That are appropriate.(AU)

Participation of the Immune System and Hedgehog Signaling in Neoangiogenesis Under Laser Photobiomodulation.

Introduction: This study aimed to characterize immune and endothelial cells, myofibroblasts and pericytes, and positive cells for hedgehog proteins in late tissue repair of rats skin wounds treated with 670 nm photobiomodulation therapy (PBMT). Methods: A blind experimental study was conducted, in order to assess the effect of PBMT in later stages of healing, with emphasis on neoangiogenesis, immune cells and Hedgehog signaling. Forty Wistar rats were allocated randomly in two groups; control and treated with a diode GaAlAs laser (9 mW, 670 nm, 0.031 W/cm2, spot size of 0.28 cm2, fluence of 4 J/ cm2 applied every other day, until a total dose of 16 J/cm2 was achieved). Standardized skin wounds were performed and the animals were euthanized at 14, 21, 28 and 35 days. Tissue sections were subjected to hematoxylin-eosin and immunohistochemistry for CD31, NG2, smooth muscle alpha actin, CD8, CD68, Ptch, Gli-2 and Ihh. All histomorphometric data were statistically analyzed and significance level was at P<0.05. Results: At late stages of wound healing, neoangiogenesis persisted as revealed for the number of CD31+ cells (P = 0.016) and NG2+ and smooth muscle alpha actin positive pericytes (P = 0.025), for both experimental groups. By day 21, laser-treated group had decreased CD68+ cells (P = 0.032) and increased CD8+ (P = 0.038). At remodeling stage, there were positive cells for the hedgehog signaling pathway family which seemed to be activated. Conclusion: These data suggest that photobiomodulation therapy was able to modulate extracellular matrix remodelling even at the later stages of wound healing.

Effect of 670 nm laser photobiomodulation on vascular density and fibroplasia in late stages of tissue repair.

This study aimed to investigate the effects of gallium-aluminum-arsenium (GaAlAs) (670 nm) laser therapy on neoangiogenesis and fibroplasia during tissue remodelling. Forty male Wistar rats underwent cutaneous surgery and were divided into 2 experimental groups: the Control and Laser group (9 mW, 670 nm, 0.031 W/cm2 , 4 J/cm2 ). After 14, 21, 28, and 35 days, the animals were euthanised. Descriptive and quantitative analyses were performed in sections stained with haematoxylin-eosin and Sirius Red, respectively. The amounts of VEGF+ and CD31+ cells were evaluated by immunohistochemistry and histomorphometric analysis, respectively. Statistical analysis was performed using the Mann-Whitney, Friedman, and Spearman correlation test, P < 0.05. The collagen expression was significantly higher in the laser group compared with the control group on days 14 and 21 after the creation of the skin wound (P = 0.008; P = 0.016) and in the control group between 14 and 28 and 14 and 35 days (P = 0.001; P = 0.007). There were more blood vessels in three periods of the study only in the (Laser) treated group, with statistical significance at day 14 (P = 0.016). There was no statistically significant difference in VEGF+ cell count in the different experimental groups throughout the study, although a positive correlation was shown with the area of collagen on days 14 and 28 (P = 0.037). Laser treatment had a positive effect in the late course of healing, particularly with regards to collagen expression and the number of newly formed vessels. VEGF+ cells were present in both experimental groups, and VEGF appeared to influence fibroplasia in the treated group.

Aspectos clínico-epidemiológicos de pacientes con infecciones asociadas a la atención de salud / Clinical-epidemiological aspects of patients with health-care associated infections

Introducción: las infecciones asociadas a la atención de salud constituyen un problema mundial por sus implicaciones económicas, legales, éticas y médicas. Objetivos: determinar el comportamiento de las infecciones asociadas a la atención de salud. Métodos: estudio descriptivo, retrospectivo y transversal de 105 pacientes con las infecciones asociadas a la atención de salud, quienes ingresaron en el servicio de medicina interna del Hospital Clínico Quirúrgico Manuel Fajardo, desde enero de 2013 hasta diciembre hasta 2015. Se utilizó la estadística descriptiva y se relacionó la información nacional e internacional con los resultados. Resultados: los pacientes afectados fueron principalmente de 60 o más años de edad, sin diferencias en el sexo. El diagnóstico más común fue la bronconeumonía (55,2 por ciento). Las principales comorbilidades resultaron ser la hipertensión arterial (52,4 por ciento), el accidente vascular encefálico (37,1 por ciento), diabetes mellitus (35,2 por ciento) y cardiopatía isquémica (35,2 por ciento). La biterapia antibiótica fue la modalidad más habitual y en la mayoría de los casos se utilizó un ciclo de antibioticoterapia, pero con frecuencia fue necesario hacer dos o más ciclos de tratamiento antibiótico. La mortalidad mostró relación significativa con la edad y predominó en pacientes de 60 o más años de edad y en los pacientes con bronconeumonía (40,3 por ciento). Conclusiones: las infecciones asociadas a la atención de salud predominaron en una población envejecida, frecuentemente asociada a comorbilidad y la mortalidad se agrupó principalmente en pacientes de la tercera edad y con bronconeumonía(AU)

Introduction: Health-care associated infections are a global problem due to their economic, legal, ethical, and medical implications. Objectives: To determine the behavior of health-care associated infections in the internal medicine service at Manuel Fajardo Hospital. Methods: Descriptive, retrospective and cross-sectional study of 105 patients with health-care associated infections was conducted. These patients were admitted to the Internal Medicine Service at Manuel Fajardo Hospital, from January 2013 to December 2015. Descriptive statistics and national and international information were related to the results. Results: The affected patients were mainly 60 or older, without differences in sex. The most common diagnosis was bronchopneumonia (55.2 percent). The main comorbidities were hypertension (52.4 percent), cerebrovascular accident (37.1 percent), diabetes mellitus (35.2 percent) and ischemic heart disease (35.2 percent). Antibiotic biotherapy was the most common modality. In most cases an antibiotic therapy cycle was used, but it was often necessary to do two or more cycles of antibiotic treatment. Mortality showed a significant relationship with age and predominated in patients who were 60 or older and in patients with bronchopneumonia (40.3 percent). Conclusions: Health-care associated infections prevailed in an aging population, frequently associated with comorbidity, and mortality was mainly grouped in elderly patients with bronchopneumonia(AU)

Aspectos clínico-epidemiológicos de pacientes con infecciones asociadas a la atención de salud / Clinical-epidemiological aspects of patients with health-care associated infections

Introducción: las infecciones asociadas a la atención de salud constituyen un problema mundial por sus implicaciones económicas, legales, éticas y médicas. Objetivos: determinar el comportamiento de las infecciones asociadas a la atención de salud. Métodos: estudio descriptivo, retrospectivo y transversal de 105 pacientes con las infecciones asociadas a la atención de salud, quienes ingresaron en el servicio de medicina interna del Hospital Clínico Quirúrgico Manuel Fajardo, desde enero de 2013 hasta diciembre hasta 2015. Se utilizó la estadística descriptiva y se relacionó la información nacional e internacional con los resultados. Resultados: los pacientes afectados fueron principalmente de 60 o más años de edad, sin diferencias en el sexo. El diagnóstico más común fue la bronconeumonía (55,2 por ciento). Las principales comorbilidades resultaron ser la hipertensión arterial (52,4 por ciento), el accidente vascular encefálico (37,1 por ciento), diabetes mellitus (35,2 por ciento) y cardiopatía isquémica (35,2 por ciento). La biterapia antibiótica fue la modalidad más habitual y en la mayoría de los casos se utilizó un ciclo de antibioticoterapia, pero con frecuencia fue necesario hacer dos o más ciclos de tratamiento antibiótico. La mortalidad mostró relación significativa con la edad y predominó en pacientes de 60 o más años de edad y en los pacientes con bronconeumonía (40,3 por ciento). Conclusiones: las infecciones asociadas a la atención de salud predominaron en una población envejecida, frecuentemente asociada a comorbilidad y la mortalidad se agrupó principalmente en pacientes de la tercera edad y con bronconeumonía(AU)

Introduction: Health-care associated infections are a global problem due to their economic, legal, ethical, and medical implications. Objectives: To determine the behavior of health-care associated infections in the internal medicine service at Manuel Fajardo Hospital. Methods: Descriptive, retrospective and cross-sectional study of 105 patients with health-care associated infections was conducted. These patients were admitted to the Internal Medicine Service at Manuel Fajardo Hospital, from January 2013 to December 2015. Descriptive statistics and national and international information were related to the results. Results: The affected patients were mainly 60 or older, without differences in sex. The most common diagnosis was bronchopneumonia (55.2 percent). The main comorbidities were hypertension (52.4 percent), cerebrovascular accident (37.1 percent), diabetes mellitus (35.2 percent) and ischemic heart disease (35.2 percent). Antibiotic biotherapy was the most common modality. In most cases an antibiotic therapy cycle was used, but it was often necessary to do two or more cycles of antibiotic treatment. Mortality showed a significant relationship with age and predominated in patients who were 60 or older and in patients with bronchopneumonia (40.3 percent). Conclusions: Health-care associated infections prevailed in an aging population, frequently associated with comorbidity, and mortality was mainly grouped in elderly patients with bronchopneumonia(AU)

Susceptibilidad antimicrobiana en muestras clínicas de pacientes con infecciones asociadas a la atención de salud / Antimicrobial susceptibility in clinical samples of patients with health care associated infections

Introducción: Las infecciones asociadas a la atención de salud (IAAS) son uno de los principales problemas que afecta a los pacientes en las unidades hospitalarias, tanto en países desarrollados como carentes de recursos. Objetivo: Identificar los tipos de IAAS reportadas, microorganismo causal y susceptibilidad antimicrobiana en el Servicio de Medicina Interna del Hospital Clínico-Quirúrgico "Manuel Fajardo". Material y método: Estudio descriptivo, retrospectivo y transversal de 105 pacientes con IAAS, quienes ingresaron en el Servicio de Medicina Interna del Hospital Clínico-Quirúrgico Manuel Fajardo, desde enero 2013 hasta diciembre 2015. Se analizaron distintas variables. Se utilizó la estadística descriptiva y se relacionó la información nacional e internacional con los resultados obtenidos. Resultados: Predominaron los pacientes con edad superior a los 60 años. El diagnóstico más común fue la bronconeumonía en 58 pacientes (55.2 por ciento). El principal microorganismo causal para la bronconeumonía, la traqueobronquitis y las úlceras de presión fue Pseudomona spp.; mientras que para la infección del tracto urinario y flebitis-celulitis y absceso fueron E. coli y S. aureus respectivamente. Pseudomona spp. y E. coli mostraron alta resistencia a las cefalosporinas de primera, segunda y tercera generaciones testadas y a otros tipos de antibióticos; sin embargo, para los aminoglucósidos y Cefepime la sensibilidad fue favorable. La susceptibilidad de S. aureus mostró resultados muy adversos, pues solo para la Amikacina y Vancomicina tuvo aceptable sensibilidad. Conclusiones: Las IAAS predominaron en una población envejecida y fueron ocasionadas por una diversidad de microorganismos, principalmente Pseudomona spp., E. coli y S. aureus, los cuales mostraron elevada resistencia antimicrobiana(AU)

Introduction: The health care associated infections (HCAI) are one of the major problems which affect the patients in the hospital units, both in developed countries and in countries with low resources. Objective: To identify what kind of HCAI were reported, causal microorganism and antimicrobial susceptibility in the Internal Medicine Service at the "Manuel Fajardo" clinical-surgical hospital. Material and method: Descriptive, retrospective and transversal study of 105 patients with HCAI, who were admitted in the Internal Medicine Service at the Manuel Fajardo clinical-surgical hospital, from January 2013 to December 2015. It was analyzed different variables. It was used descriptive statistics and it was related the national and international information with the obtained results. Results: It were predominated the patients with age over 60 years. The more common diagnosis was broncho-pneumonia in 58 patients (55.2 percent). The principal causal microorganism for broncho-pneumonia, the tracheo-bronchitis and the pressure ulcers was Pseudomona spp.; while for urinary tract infection and flebitis-cellulitis and abscess were E. coli and S. aureus respectively. Pseudomona spp. and E. coli showed high resistance to cephalosporins of the first, second and third generation tested and other kinds of antibiotics; however, for the amynoglucosides and for Cefepime the sensibility was favourable. The susceptibility of S. aureus showed very adverse results, because only for Amikacin and Vancomicin had acceptable sensibility. Conclusions: The HCAI predominated in an aged population and were caused by a diversity of microorganisms, principally Pseudomona spp., E. coli and S. aureus, which showed high antimicrobial resistance(AU)

Wound healing - A literature review.

Regeneration and tissue repair processes consist of a sequence of molecular and cellular events which occur after the onset of a tissue lesion in order to restore the damaged tissue. The exsudative, proliferative, and extracellular matrix remodeling phases are sequential events that occur through the integration of dynamic processes involving soluble mediators, blood cells, and parenchymal cells. Exsudative phenomena that take place after injury contribute to the development of tissue edema. The proliferative stage seeks to reduce the area of tissue injury by contracting myofibroblasts and fibroplasia. At this stage, angiogenesis and reepithelialization processes can still be observed. Endothelial cells are able to differentiate into mesenchymal components, and this difference appears to be finely orchestrated by a set of signaling proteins that have been studied in the literature. This pathway is known as Hedgehog. The purpose of this review is to describe the various cellular and molecular aspects involved in the skin healing process.

Wound healing - A literature review

Abstract: Regeneration and tissue repair processes consist of a sequence of molecular and cellular events which occur after the onset of a tissue lesion in order to restore the damaged tissue. The exsudative, proliferative, and extracellular matrix remodeling phases are sequential events that occur through the integration of dynamic processes involving soluble mediators, blood cells, and parenchymal cells. Exsudative phenomena that take place after injury contribute to the development of tissue edema. The proliferative stage seeks to reduce the area of tissue injury by contracting myofibroblasts and fibroplasia. At this stage, angiogenesis and reepithelialization processes can still be observed. Endothelial cells are able to differentiate into mesenchymal components, and this difference appears to be finely orchestrated by a set of signaling proteins that have been studied in the literature. This pathway is known as Hedgehog. The purpose of this review is to describe the various cellular and molecular aspects involved in the skin healing process.

Immunohistochemical evaluation of hedgehog signalling in epithelial/mesenchymal interactions in squamous cell carcinoma transformation: a pilot study.

Precancerous lesions have been studied because of their carcinogenic potential and their association with squamous cell carcinoma (SCC) has been reported. In the tumour microenvironment, the processes of angiogenesis and tissue remodelling are regulated by a family of proteins (Hedgehog) described as being able to modulate epithelial/mesenchymal interactions. The objective of this study was to perform a comparative study of precancerous lesions and SCCs by immunohistochemistry for the presence of Sonic, Gli2, SMO and Patched proteins, members of the Hedgehog pathway. Sixteen cases diagnosed as actinic cheilitis associated with SCC were compared to normal oral mucosa. The sections were subjected to immunohistochemistry and the positively stained cells were counted by morphometric analysis. There was a significant progressive increase in expression of all proteins of the Hedgehog pathway, both in the epithelium and in the connective tissue, when sections of normal mucosa, dysplasia and carcinoma were compared (P < 0.05). Thus, one may suggest that the Hedgehog pathway in tumour transformation influences SCC, and more studies should be conducted to expand the understanding of the role of these proteins in neoplastic transformation.

Estrategia metodológica para potenciar la evaluación del aprendizaje en las Clases Prácticas Integrales de la Lengua Inglesa / Methodological strategy to enhance teaching assessment in the Integrated Practical English Language Lessons

Introducción: el idioma inglés ocupa un lugar entre las disciplinas académicas que forman parte de los estudios de las Ciencias Médicas. En la educación médica superior cubana, los objetivos educacionales constituyen la categoría rectora del proceso docente-educativo; pero no hay dudas de que la evaluación influye en lo que enseñamos y determina de manera directa lo que los educandos aprenden. Objetivo: se realizó una investigación con el objetivo de valorar la evaluación del aprendizaje. Método: se entregó a 10 profesores del Departamento de Inglés de la Universidad de Ciencias Médicas de Ciego de Ávila una propuesta metodológica para potenciar la evaluación del aprendizaje en las Clases Prácticas Integrales de la Lengua Inglesa. Resultados: se considera muy adecuada la estrategia metodológica para potenciar la evaluación en las Clases Prácticas Integrales de la Lengua Inglesa. Conclusiones: esta estrategia repercute de manera positiva en el mejoramiento del desempeño de los estudiantes y profesores(AU)

Introduction: the English language has a place among the academic disciplines that are part of the studies of Medical Sciences. in Cuban higher medical education, the educational objectives are the governing category of the educational process; but there is no doubt that evaluation influences what we teach and directly determines the way that students learn. Objective: an investigation was carried out to assess the evaluation of learning. Method: in order to foster the evaluation in the English teaching process, a methodological strategy was proposed and provided to the English staff. Results: it is considered very appropriate the methodological strategy to strengthen comprehensive evaluation in the Integrated Practical English Language Lessons. Conclusions: this strategy has a positive effect on improving the performance of students and teachers(AU)

Dysregulated cholinergic network as a novel biomarker of poor prognostic in patients with head and neck squamous cell carcinoma.

BACKGROUND: In airways, a proliferative effect is played directly by cholinergic agonists through nicotinic and muscarinic receptors activation. How tumors respond to aberrantly activated cholinergic signalling is a key question in smoking-related cancer. This research was addressed to explore a possible link of cholinergic signalling changes with cancer biology. METHODS: Fifty-seven paired pieces of head and neck squamous cell carcinoma (HNSCC) and adjacent non-cancerous tissue (ANCT) were compared for their mRNA levels for ACh-related proteins and ACh-hydrolyzing activity. RESULTS: The measurement in ANCT of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities (5.416 ± 0.501 mU/mg protein and 6.350 ± 0.599 mU/mg protein, respectively) demonstrated that upper respiratory tract is capable of controlling the availability of ACh. In HNSCC, AChE and BChE activities dropped to 3.584 ± 0.599 mU/mg protein (p = 0.002) and 3.965 ± 0.423 mU/mg protein (p < 0.001). Moreover, tumours with low AChE activity and high BChE activity were associated with shorter patient overall survival. ANCT and HNSCC differed in mRNA levels for AChE-T, α3, α5, α9 and ß2 for nAChR subunits. Tobacco exposure had a great impact on the expression of both AChE-H and AChE-T mRNAs. Unaffected and cancerous pieces contained principal AChE dimers and BChE tetramers. The lack of nerve-born PRiMA-linked AChE agreed with pathological findings on nerve terminal remodelling and loss in HNSCC. CONCLUSIONS: Our results suggest that the low AChE activity in HNSCC can be used to predict survival in patients with head and neck cancer. So, the ChE activity level can be used as a reliable prognostic marker.

Unbalanced acetylcholinesterase activity in larynx squamous cell carcinoma.

Previous reports have demonstrated that a non-neuronal cholinergic system is expressed aberrantly in airways. A proliferative effect is exerted directly by cholinergic agonists through the activation of nicotinic and muscarinic receptors. In cancer, particularly those related with smoking, the mechanism through which tumour cells respond to aberrantly activated cholinergic signalling is a key question. Fifty paired pieces of larynx squamous cell carcinoma and adjacent non-cancerous tissue were compared in terms of their acetylcholinesterase activity (AChE). The AChE activity in non-cancerous tissues (0.248 ± 0.030 milliunits per milligram of wet tissue; mU/mg) demonstrates that upper respiratory tissues express sufficient AChE activity for controlling the level of acetylcholine (ACh). In larynx carcinomas, the AChE activity decreased to 0.157 ± 0.024 mU/mg (p=0.009). Larynx cancer patients exhibiting low ACh-degrading enzymatic activity had a significantly shorter overall survival (p=0.031). Differences in the mRNA levels of alternatively spliced AChE isoforms and molecular compositions were noted between glottic and supraglottic cancers. Our results suggest that the low AChE activity observed in larynx squamous cell carcinoma may be useful for predicting the outcome of patients.

Sistema de ejercicios para erradicar las dificultades con los verbos en la tercera persona del singular en el idioma inglés / System of exercises to erradicate the difficulties related to the third person singular of verbs in English language

Se realizó un estudio pre-experimental con la cantidad de 73 estudiantes de 1er año de la carrera de medicina a los que se le aplicó un instrumento evaluativo antes y después de introducir la propuesta. La investigación demuestra la efectividad de la utilización de los ejercicios sugeridos para erradicar los problemas existentes a la hora de conjugar la tercera persona del singular y dar respuesta a las interrogantes de los alumnos sobre estas particularidades. Con respecto a los resultados obtenidos como se podrá ver en las tablas, la comparación con otros grupos que no participaron es otro aspecto favorable a tomar en consideración (AU)

A pre-experimental study was carried out with 73 students from the first year of medicine carrier where an evaluative instrument was applied before and after to introduce the proposal. This study shows the effectiveness of the exercises created to eradicate the problems the students may face when they are going to use the third person singular related to the lexical structure of the verbs. Regarding the results obtained, the comparison with other groups which did not take part in the study is another favorable aspect to be considered (AU)

Dr. José Luis Candelario, ícono de la Medicina avileña / Dr. José Luis Candelario, icon of Ciego de Avila Medicine

En el presente trabajo se presenta la biografía del Dr. José Luis Candelario Álvarez, Especialista en Segundo Grado en Ortopedia y Traumatología, Profesor Auxiliar en esta especialidad, con el objetivo de estudiar la vida de quien es considerado un destacado médico de la provincia Ciego de Ávila, quien constituye un ejemplo a imitar por profesionales y estudiantes de las carreras de la salud; dar a conocer su semblanza contribuye de forma positiva a la formación de valores éticos y humanos, tales como la responsabilidad, el sacrificio, honestidad y consagración en los profesionales de la salud. Se recopilaron fotos, datos y documentos relacionados con su figura y su fecunda trayectoria, información personal y profesional a través de entrevistas a sus alumnos, compañeros de trabajo y familiares, lo que permitió la elaboración de este artículo para dar a conocer su labor asistencial e investigativa y los méritos alcanzados durante toda su trayectoria (AU)

In this research it was selected Dr. José Luis Candelario Alvarez Second Degree Specialist in Orthopedics and Traumatology and Assistant Professor in this field, with the aim of studying the life of who is considered a leading doctor in our province, being a good example for professionals and students in the health field, which contributes positively to the formation of ethical and human values​​, such as responsibility, sacrifice, honesty and commitment to health professionals. It were collected photos, data and documents related to his figure and his fruitful career, all the necessary information through personal interviews, to his students, colleagues and family. This allowed the preparation of this work to publish their nursing care and research and merits achieved throughout his life (AU)

Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.

This study evaluated the influence of hypothalamic-pituitary-adrenal (HPA) axis in cutaneous wounds subjected to laser biomodulation. A total of 48 rats were divided into two groups: Group I (GI) with 24 adrenalectomized animals and Group II (GII) with 24 non-adrenalectomized animals. Each group was divided into two subgroups: the irradiated subgroup which laser was applied to four points at the edges of the wound (670 nm laser, 9 mW) and control subgroup. Rats in each subgroup were sacrificed at 24 or 72 h. Adrenal glands were only removed from GI rats. Three days after adrenalectomy, a cutaneous wound was made. An immunohistochemical analysis was performed using anti-CD45 and anti-CD8 antibodies. Flow cytometry was used to count T lymphocytes and their subpopulations in blood. Decreases in the number of CD45-positive inflammatory cells and in the total numbers of CD8- and CD45-positive cells were observed in histological sections of adrenalectomized animals subjected to laser biomodulation at 24h. Similar results were observed for distribution of total lymphocytes in blood (p<0.05). The action of 670 nm laser does not depend exclusively on HPA axis. It is believed that corticosteroid-promoting enzymes liberated in non-adrenal tissues may influence immune response under the influence of this type of phototherapy.

Logros en la competencia comunicativa a través de la utilización de la música en las clases de Inglés / Achievements in the communicative competence through the use of music in the English classes

Se realizó un estudio pre-experimental con la cantidad de 50 estudiantes de 2do año de la carrera de Medicina a los que se le aplicó un instrumento evaluativo para conocer los logros en la competencia comunicativa a través de la utilización de la música en las clases de Inglés. Ese instrumento fue aplicado antes y después de introducir las canciones y se obtuvo como resultado una elevación del nivel de asimilación y comprensión de conocimientos y habilidades que necesitan los estudiantes en el estudio de la Lengua Inglesa(AU)

A pre-experimental study was conducted with 50 students from the second year of the Medicine career. We applied and evaluated an instrument to know the level of knowledge acquired by them when introducing the music in the English lessons. That instrument was applied before and after introducing the different exercises, obtaining as results an elevation of the level of assimilation and comprehension of knowledge that the students need in the study of the English language(AU)

Logros en la competencia comunicativa a través de la utilización de la música en las clases de Inglés / Achievements in the communicative competence through the use of music in the English classes

Se realizó un estudio pre-experimental con la cantidad de 50 estudiantes de 2do año de la carrera de Medicina a los que se le aplicó un instrumento evaluativo para conocer los logros en la competencia comunicativa a través de la utilización de la música en las clases de Inglés. Ese instrumento fue aplicado antes y después de introducir las canciones y se obtuvo como resultado una elevación del nivel de asimilación y comprensión de conocimientos y habilidades que necesitan los estudiantes en el estudio de la Lengua Inglesa.

A pre-experimental study was conducted with 50 students from the second year of the Medicine career. We applied and evaluated an instrument to know the level of knowledge acquired by them when introducing the music in the English lessons. That instrument was applied before and after introducing the different exercises, obtaining as results an elevation of the level of assimilation and comprehension of knowledge that the students need in the study of the English language.

Impact of court rulings on health care coverage: the case of HIV/AIDS in Colombia.

This article addresses an emerging issue in health care systems: the impact of judicial rulings on public policy regarding financing and delivery of health care services, and the attendant tensions, contradictions and questions. In Colombia, HIV/AIDS patients' use of a legal instrument called tutela, or writ of protection, has produced abundant jurisprudence and prompted health authorities to respond with decisions about HIV/AIDS service coverage that do not consider epidemiologic criteria and sustainability, introducing distortions in the health care system with respect to financing, priority-setting and universality.

Desarrollo de habilidades lingüísticas en estudiantes de 1er año de la carrera de Medicina / Development of linguistics skills in 1st year students of Medicine career

Se realizó un estudio pre-experimental con la cantidad de 40 estudiantes de 1er año de la carrera de Medicina a los que se le aplicó un instrumento evaluativo para conocer el nivel de conocimientos adquirido por ellos al integrar las 4 habilidades lingüísticas en la comprensión del idioma Inglés. Ese instrumento fue aplicado antes y después de integrar las 4 habilidades básicas obteniendo como resultados una elevación del nivel de asimilación y comprensión de conocimientos y habilidades que necesitan los estudiantes en el estudio de la Lengua Inglesa (AU)

A pre-experimental study was done with a quantity of 40 students from 1st year of Medicine career to those we applied an evaluated instrument to the level of knowledge acquired by them when integrating the four basic abilities to the comprehension of English subject. That instrument was applied before and after integrating the four basic abilities obtaining as results an elevation of the level of assimilation and comprehension of knowledge that needed the students in the study of the English language (AU)

Desarrollo de habilidades lingüísticas en estudiantes de 1er año de la carrera de Medicina / Development of linguistics’ skills in 1st year students of Medicine career

Se realizó un estudio pre-experimental con la cantidad de 40 estudiantes de 1er año de la carrera de Medicina a los que se le aplicó un instrumento evaluativo para conocer el nivel de conocimientos adquirido por ellos al integrar las 4 habilidades lingüísticas en la comprensión del idioma Inglés. Ese instrumento fue aplicado antes y después de integrar las 4 habilidades básicas obteniendo como resultados una elevación del nivel de asimilación y comprensión de conocimientos y habilidades que necesitan los estudiantes en el estudio de la Lengua Inglesa.

A pre-experimental study was done with a quantity of 40 students from 1st year of Medicine career to those we applied an evaluated instrument to the level of knowledge acquired by them when integrating the four basic abilities to the comprehension of English subject. That instrument was applied before and after integrating the four basic abilities obtaining as results an elevation of the level of assimilation and comprehension of knowledge that needed the students in the study of the English language.