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Am J Trop Med Hyg ; 69(3): 263-8, 2003 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-14628942

RESUMO

Following an outbreak of hantavirus pulmonary syndrome (HPS) in the Paraguayan Chaco in 1995, Calomys laucha was identified as the rodent host for the hantavirus associated with these cases. To explore the possibility of additional hantaviruses in Paraguay, we collected 636 mammals from 10 of the 17 departments. Plasma from 27 animals in Alto Paraguay and Boquer6n in the Chaco and Neembucú and Itapúa in the eastern region had antibody to Andes virus antigens. Of these 27, five individuals (among four species) were positive for hantavirus RNA. Sera were collected from indigenous people in eastern Paraguay to ascertain whether persons were being infected with hantavirus outside of the Chaco. Seventeen percent were antibody-positive. These results suggest that several different hantaviruses are co-circulating in Paraguay, and that HPS cases occurring in eastern Paraguay may result from exposure to hantaviruses that are distinct from those in the Chaco.


Assuntos
Anticorpos Antivirais/análise , Reservatórios de Doenças , Infecções por Hantavirus/epidemiologia , Orthohantavírus/imunologia , Roedores/virologia , Adolescente , Adulto , Idoso , Animais , Anticorpos Antivirais/sangue , Criança , Primers do DNA , Feminino , Orthohantavírus/genética , Orthohantavírus/isolamento & purificação , Infecções por Hantavirus/sangue , Infecções por Hantavirus/etiologia , Humanos , Immunoblotting , Masculino , Pessoa de Meia-Idade , Testes de Neutralização , Paraguai/epidemiologia , Grupos Populacionais/estatística & dados numéricos , RNA Viral/análise , RNA Viral/sangue , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Roedores/classificação
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