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Curr Probl Cardiol ; 49(7): 102628, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38729276

RESUMO

Mechanical prosthetic valve thrombosis (MPVT) is a common complication of valvular implantations. This study compared the efficacy and safety of different treatments for MPVT. A systematic search of electronic databases identified studies evaluating surgical, anticoagulant, and thrombolytic therapies. Although several studies of different types have been conducted to evaluate the efficacy of these treatment strategies the lack of randomized controlled trials has resulted in the inability to make a definitive conclusion about the pros and cons of these treatments. Recent treatments, such as slow and ultraslow infusion of thrombolytics, showed comparable efficacy and lower complication rates than traditional methods. Inadequate anticoagulant use is a major risk factor for MPVT, highlighting the importance of prevention. Treatment selection should be individualized based on patient factors and available expertise. Overall, slow and ultraslow infusion of thrombolytics may be a promising treatment option for MPVT.


Assuntos
Anticoagulantes , Fibrinolíticos , Próteses Valvulares Cardíacas , Terapia Trombolítica , Trombose , Humanos , Próteses Valvulares Cardíacas/efeitos adversos , Trombose/etiologia , Trombose/prevenção & controle , Terapia Trombolítica/métodos , Terapia Trombolítica/efeitos adversos , Fibrinolíticos/uso terapêutico , Anticoagulantes/uso terapêutico , Fatores de Risco , Implante de Prótese de Valva Cardíaca/efeitos adversos , Implante de Prótese de Valva Cardíaca/métodos , Resultado do Tratamento
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