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1.
Comput Biol Med ; 43(6): 765-74, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23668353

RESUMO

The purpose of this study is to implement accurate methods of detection and classification of benign and malignant breast masses in mammograms. Our new proposed method, which can be used as a diagnostic tool, is denoted Local Seed Region Growing-Spherical Wavelet Transform (LSRG-SWT), and consists of four steps. The first step is homomorphic filtering for enhancement, and the second is detection of the region of interests (ROIs) using a Local Seed Region Growing (LSRG) algorithm, which we developed. The third step incoporates Spherical Wavelet Transform (SWT) and feature extraction. Finally the fourth step is classification, which consists of two sequential components: the 1st classification distinguishes the ROIs as either mass or non-mass and the 2nd classification distinguishes the masses as either benign or malignant using a Support Vector Machine (SVM). The mammograms used in this study were acquired from the hospital of Istanbul University (I.U.) in Turkey and the Mammographic Image Analysis Society (MIAS). The results demonstrate that the proposed scheme LSRG-SWT achieves 96% and 93.59% accuracy in mass/non-mass classification (1st component) and benign/malignant classification (2nd component) respectively when using the I.U. database with k-fold cross validation. The system achieves 94% and 91.67% accuracy in mass/non-mass classification and benign/malignant classification respectively when using the I.U. database as a training set and the MIAS database as a test set with external validation.


Assuntos
Algoritmos , Neoplasias da Mama/diagnóstico por imagem , Mamografia/métodos , Modelos Teóricos , Intensificação de Imagem Radiográfica/métodos , Análise de Ondaletas , Neoplasias da Mama/classificação , Bases de Dados Factuais , Feminino , Humanos
2.
J Med Syst ; 34(6): 1083-8, 2010 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-20703600

RESUMO

The objective of this paper is to demonstrate the utility of artificial neural networks, in combination with wavelet transforms for the detection of mammogram masses as malign or benign. A total of 45 patients who had breast masses in their mammography were enrolled in the study. The neural network was trained on the wavelet based feature vectors extracted from the mammogram masses for both benign and malign data. Therefore, in this study, Multilayer ANN was trained with the Backpropagation, Conjugate Gradient and Levenberg-Marquardt algorithms and ten-fold cross validation procedure was used. A satisfying sensitivity percentage of 89.2% was achieved with Levenberg-Marquardt algorithm. Since, this algorithm combines the best features of the Gauss-Newton technique and the other steepest-descent algorithms and thus it reaches desired results very fast.


Assuntos
Neoplasias da Mama/diagnóstico , Mamografia , Redes Neurais de Computação , Análise de Ondaletas , Algoritmos , Neoplasias da Mama/patologia , Feminino , Humanos , Interpretação de Imagem Assistida por Computador , Sensibilidade e Especificidade , Turquia
3.
J Med Syst ; 34(6): 993-1002, 2010 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-20703608

RESUMO

Breast cancer continues to be a significant public health problem in the world. The diagnosing mammography method is the most effective technology for early detection of the breast cancer. However, in some cases, it is difficult for radiologists to detect the typical diagnostic signs, such as masses and microcalcifications on the mammograms. This paper describes a new method for mammographic image enhancement and denoising based on wavelet transform and homomorphic filtering. The mammograms are acquired from the Faculty of Medicine of the University of Akdeniz and the University of Istanbul in Turkey. Firstly wavelet transform of the mammograms is obtained and the approximation coefficients are filtered by homomorphic filter. Then the detail coefficients of the wavelet associated with noise and edges are modeled by Gaussian and Laplacian variables, respectively. The considered coefficients are compressed and enhanced using these variables with a shrinkage function. Finally using a proposed adaptive thresholding the fine details of the mammograms are retained and the noise is suppressed. The preliminary results of our work indicate that this method provides much more visibility for the suspicious regions.


Assuntos
Aumento da Imagem/métodos , Mamografia/normas , Análise de Ondaletas , Neoplasias da Mama/diagnóstico , Feminino , Humanos , Turquia
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