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1.
Dokl Biochem Biophys ; 513(Suppl 1): S36-S52, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38472664

RESUMO

Study of swirling flows in channels corresponding to the static approximation of flow channels of the heart and major vessels with a longitudinal-radial profile zR2 = const and a concave streamlined surface at the beginning of the longitudinal coordinate has been carried out. A comparative analysis of the flow structure in channel configurations zRN = const, where N = -1, 1, 2, 3, in the absence and presence of a concave surface was carried out. The numerical modeling was compared with the results of hydrodynamic experiments on the flow characteristics and the shape of the flow lines. The numerical model was used to determine the velocity structure, viscous friction losses, and shear stresses. Numerical modeling of steady-state flows for channels without a concave surface showed that in the channel zR2 = const there is a stable vortex flow structure with the lowest viscous friction losses. The presence of a concave surface of sufficient size significantly reduces viscous friction losses and shear stresses in both the steady state and pulsed modes.


Assuntos
Hemodinâmica , Modelos Cardiovasculares , Hemodinâmica/fisiologia , Aorta , Simulação por Computador , Coração
2.
Usp Fiziol Nauk ; 47(1): 48-68, 2016.
Artigo em Russo | MEDLINE | ID: mdl-27149823

RESUMO

New approach to intracardiac blood flow condition analysis based on geometric parameters of left ventricle flow channel has been suggested. Parameters, that used in this method, follow from exact solutions of nonstationary Navier-Stocks equations for selforganized tornado-like flows of viscous incompressible fluid. The main advantage of this method is considering dynamic anatomy of intracardiac cavity and trabeculae relief of left ventricle streamlined surface, both registered in a common mri-process, as flow condition indicator. Calculated quantity options that characterizes blood flow condition can be use as diagnostic criterias for estimation of violation in blood circulation function which entails heart ejection reduction. Developed approach allows to clarify heart jet organization mechanism and estimate the share of the tornado-like flow self-organization in heart ejection structure.


Assuntos
Cardiomiopatia Hipertrófica/fisiopatologia , Ventrículos do Coração/fisiopatologia , Modelos Cardiovasculares , Velocidade do Fluxo Sanguíneo , Cardiomiopatia Hipertrófica/patologia , Ventrículos do Coração/patologia , Humanos , Volume Sistólico , Viscosidade
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