Search for magnetic monopoles produced via the Schwinger mechanism.

Electrically charged particles can be created by the decay of strong enough electric fields, a phenomenon known as the Schwinger mechanism1. By electromagnetic duality, a sufficiently strong magnetic field would similarly produce magnetic monopoles, if they exist2. Magnetic monopoles are hypothetical fundamental particles that are predicted by several theories beyond the standard model3-7 but have never been experimentally detected. Searching for the existence of magnetic monopoles via the Schwinger mechanism has not yet been attempted, but it is advantageous, owing to the possibility of calculating its rate through semi-classical techniques without perturbation theory, as well as that the production of the magnetic monopoles should be enhanced by their finite size8,9 and strong coupling to photons2,10. Here we present a search for magnetic monopole production by the Schwinger mechanism in Pb-Pb heavy ion collisions at the Large Hadron Collider, producing the strongest known magnetic fields in the current Universe11. It was conducted by the MoEDAL experiment, whose trapping detectors were exposed to 0.235 per nanobarn, or approximately 1.8 × 109, of Pb-Pb collisions with 5.02-teraelectronvolt center-of-mass energy per collision in November 2018. A superconducting quantum interference device (SQUID) magnetometer scanned the trapping detectors of MoEDAL for the presence of magnetic charge, which would induce a persistent current in the SQUID. Magnetic monopoles with integer Dirac charges of 1, 2 and 3 and masses up to 75 gigaelectronvolts per speed of light squared were excluded by the analysis at the 95% confidence level. This provides a lower mass limit for finite-size magnetic monopoles from a collider search and greatly extends previous mass bounds.

Impact of Social Frailty on Relocation of Older Adults.

BACKGROUND: The relationship between frailty and variables such as housing are the least included in models of frailty and research on frailty or social frailty and relocation is negligible. The decision to relocate is complex and demanding for older adults with a loss of independence but little is known about what makes older adults relocate to congregated housing designated for older adults, let alone in combination with social frailty, and how they navigate this transition. OBJECTIVES: This mixed method descriptive study aims to understand the influence of social frailty for a population of French-speaking semi-independent older adults relocating to a housing continuum community. DESIGN: Semi-structured individual interviews including sociodemographic data and the PRISMA-7 Frailty Scale were conducted with recently relocated older adults. SETTING: A newly opened French-speaking housing continuum community in Eastern Canada that offers luxury apartments for independent older adults, two assisted living facilities for semi-independent older adults along with a long-term care facility. PARTICIPANTS: Twenty-nine older adults with a mean age of 85 years, mostly female, married or widowed and highly educated. MEASUREMENTS: Content analysis of the transcribed recorded interviews and descriptive statistical analyses to examine relationships between the frailty PRISMA-7 scale, answers to additional questions and the sociodemographic data. RESULTS: There was not a significant difference in the scores for socialization before and after relocation nor between prior help and current help; however, there was a significant negative correlation between help and socialization before and after relocation. Three main themes included: imposed influences, push and pull factors and post relocation. CONCLUSIONS: The results indicate that several social factors contributed to relocation and that participants were experiencing social frailty. Participants were at the crossover point of being vulnerable to experiencing additional deficits which would potentially have led to higher frailty had they not relocated.

Feasibility of perioperative volatile organic compound breath testing for prediction of paralytic ileus following laparoscopic colorectal resection.

BACKGROUND: Despite implementation of enhanced recovery after surgery (ERAS) and laparoscopic techniques, postoperative ileus (POI) remains frequent after colorectal surgery, impacting the patient, their recovery and health-care resources. Presently there are no tests that reliably predict or enable early POI diagnosis. Volatile organic compounds (VC) are products of human and microbiota cellular metabolism and we hypothesised that a detectable alteration occurs in POI. METHOD: This was a prospective observational study of patients undergoing laparoscopic colorectal resection within an established ERAS programme. Standardized end-expiratory breath sampling was performed on the morning of surgery and on the first three postoperative mornings. The concentrations of VCs commonly found in intestinal gas were analysed using selected ion flow tube mass spectrometry and GastroCH4 ECK®. Feasibility data, bowel preparation, postoperative oral intake, POI and 30-day morbidity were recorded. RESULTS: Of the 75 potentially eligible patients, 58 (77%) agreed to participate. Per-protocol breath sampling was successfully completed in 94%. There were no analytical failures. Baseline and postoperative concentrations of VCs were broadly comparable and were not altered by bowel preparation or postoperative oral intake. POI developed in 14 (29%) patients. Preoperative ammonia concentration was higher in patients who developed POI [830 parts per billion (ppb) vs 510 ppb, P = 0.027]. There was an increase in the concentration of acetic acid detected on day 2 in patients who developed POI (99 ppb vs 171 ppb, P = 0.021). CONCLUSION: Repeated VC breath sampling and analysis is feasible in the perioperative setting. An elevated ammonia concentration on the morning of surgery may be a potential predictor of POI.

The Brookhaven National Laboratory electron beam ion source for RHIC.

As part of a new heavy ion preinjector that will supply beams for the Relativistic Heavy Ion Collider and the National Aeronautics and Space Administration Space Radiation Laboratory, construction of a new electron beam ion source (EBIS) is now being completed. This source, based on the successful prototype Brookhaven National Laboratory Test EBIS, is designed to produce milliampere level currents of all ion species, with q/m=(1/6)-(1/2). Among the major components of this source are a 5 T, 2-m-long, 204 mm diameter warm bore superconducting solenoid, an electron gun designed to operate at a nominal current of 10 A, and an electron collector designed to dissipate approximately 300 kW of peak power. Careful attention has been paid to the design of the vacuum system, since a pressure of 10(-10) Torr is required in the trap region. The source includes several differential pumping stages, the trap can be baked to 400 C, and there are non-evaporable getter strips in the trap region. Power supplies include a 15 A, 15 kV electron collector power supply, and fast switchable power supplies for most of the 16 electrodes used for varying the trap potential distribution for ion injection, confinement, and extraction. The EBIS source and all EBIS power supplies sit on an isolated platform, which is pulsed up to a maximum of 100 kV during ion extraction. The EBIS is now fully assembled, and operation will be beginning following final vacuum and power supply tests. Details of the EBIS components are presented.

Self-reported medication adherence and health status in late adulthood: the role of beliefs.

In this study, we explore the role of subjective beliefs in determining self-reports of medication adherence and health status in 90 older adults (M age = 71.7 years, SD = 7.44). Self-reported adherence was predicted by personal health locus of control beliefs, but not by medical factors nor beliefs regarding one's own health care professionals. Self-reported health was predicted by medical factors, perceptions of one's health care professional, and health locus of control. These results suggest that self-reported adherence is primarily a belief-laden construct whereas self-reported health consists of both an objective assessment of health and a subjective belief-laden component. Exploratory analyses conducted on younger-old and older-old age groups indicated that medical factors may be less important to older-old adults' perceived health status than the younger-old adults.

Metacognition and medication adherence: how do older adults remember?

Fifty-one older adults (M age = 75.9 years, SD = 6.9) reported their use of memory strategies for taking of medication using the Prospective Memory for Medication Questionnaire. Older adults used internal strategies more often when the domain was restricted to medication taking but used external strategies more often when queried across a variety of everyday situations. Surprisingly, the hypothesis that medical factors would be the primary determinants of older adults' reports of memory strategy use and perceived adherence was not supported. Metamemorial variables of non-domain-specific memory self-efficacy and memory anxiety in everyday life were significant predictors of strategy use and perceived adherence over and above variables related to the domain of health.

Getting to know you: how own age and other's age relate to self-disclosure.

In this study, we compared self-disclosures made in ten same-aged (young-young) and ten mixed-aged (young-old) conversational dyads. We developed a scoring scheme to code get-acquainted conversations on amount, type, valence, and intimacy of self-disclosure (S-Ds). Overall, young women produced more S-Ds with same-aged than with older partners. Young women devoted marginally fewer of their self-disclosures to statements about the past than did older women. Younger and older women's S-Ds about the present and the past were not significantly different in how negative, positive, or intimate they were. The intimacy and negativity of disclosures made by the dyad members were more closely correlated in young-young than in young-old dyads. Young participants' affective reports following the conversations did not differ as a function of partner age, but did correlate with aspects of their partners' self-disclosures. Findings offer a contrast to the stereotype that older adults dominate conversations with intimate, negative disclosures about the past.

How we spent our vacation: collaborative storytelling by young and old adults.

Young and old dyads collaborated in describing a mutually experienced event. Three general aspects of the vacation descriptions of 10 younger (M = 28.5 years) and 10 older (M = 70.7 years) married couples were examined. First, regarding the structure of the stories, the older adults' speech contained longer clauses, and they were less likely to situate an event in absolute time than were the younger adults. Second, regarding the content of the stories, older couples' discourse was more subjective, with more descriptions of places and people and fewer descriptions of itineraries than younger couples'. Third, regarding the interactions of the collaborators, the older couples produced fewer words of support for their spouse and more monologues than did the younger couples. This pattern of findings may result from a strategy by the elderly storytellers to decrease the memory demands of the task and the cognitive demands of the collaboration.

Adult age differences in elaborations produced during prose recall.

This study focused on adult age differences in the characteristics and quantity of elaborations produced during a prose recall task. Young (M = 24.3 years) and older (M = 67.9 years) adults were tested in 3 same-age, same-gender group size conditions: individual, dyad, and tetrad. Elaborations, which are statements not contained in the text but not inconsistent with it, were divided into 2 major categories. Denotative elaborations included statements that were closely related to the text and filled in gaps in the stories. These elaborations were equally produced by young and older adults and were significantly correlated with gist recall performance. Annotative elaborations were evaluative and interpretive comments. These statements were more frequently produced by older adults but were not correlated with recall performance. Young and older adults had different patterns of annotative elaboration production across group size conditions.