1.
Bioorg Med Chem Lett
; 26(1): 25-32, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26627579
RESUMO
Chemical modulation of a formerly disclosed DGAT-1 inhibitor resulted in the identification of a compound with a suitable profile for preclinical development. Optimisation of solubility is discussed and a PK/PD study is presented.