1.
Nanoscale
; 9(12): 4048-4052, 2017 Mar 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28276559
RESUMO
Herein, we report a novel approach for the design of a colorimetric aptasensor based on functionalized gold nanoparticle probes. This approach relies on the conjugation of nanoparticles by two functional DNA and RNA hairpins that engage specific kissing (loop-loop) interactions in response to the addition of a small analyte ligand, leading to particle aggregation and then red-to-purple colour change of the colloidal solution.