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J Gastrointest Surg ; 11(11): 1573-5, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-17436049

RESUMO

Gastric neuroendocrine tumors (carcinoids) are relatively uncommon neoplasms. Some 70 to 80% of these lesions occur in patients with autoimmune body gastritis. This disorder, however, is also a risk factor for the development of conventional gastric adenocarcinomas. We report a case of a patient with autoimmune body gastritis and a well-differentiated neuroendocrine tumor of the stomach, which was removed with endoscopic full-thickness resection in sano upon signs of invasive growth several years after its first diagnosis. Histological examination surprisingly showed a composite glandular-endocrine gastric carcinoma. We discuss the histopathological genesis of the tumor and provide evidence that endoscopic full-thickness resection might be an oncologically appropriate minimally invasive treatment for such gastric lesions.


Assuntos
Adenocarcinoma/patologia , Tumores Neuroendócrinos/patologia , Neoplasias Gástricas/patologia , Adenocarcinoma/metabolismo , Diferenciação Celular , Cromogranina A/metabolismo , Feminino , Humanos , Imuno-Histoquímica , Masculino , Pessoa de Meia-Idade , Tumores Neuroendócrinos/metabolismo , Neoplasias Gástricas/metabolismo
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