RESUMO
A 75-year-old female patient presented with bilateral progressive loss of vision. Best corrected visual acuity (BCVA) was hand movements in the right eye and 1/50 in the left eye. The spectral domain optical coherence tomography (SD-OCT) showed thinning of the outer retina suspected to be due to autoimmune retinopathy. A neuroendocrine carcinoma of the uterus was diagnosed during tumor screening. Under systemic therapy with corticosteroids the visual acuity improved to 20/200 in the right eye and 20/80 in the left eye. Cancer-associated retinopathy (CAR) is a paraneoplastic autoimmune retinopathy.
Assuntos
Doenças Autoimunes , Carcinoma Neuroendócrino , Síndromes Paraneoplásicas Oculares , Doenças Retinianas , Neoplasias Uterinas/complicações , Idoso , Carcinoma Neuroendócrino/complicações , Feminino , Humanos , Doenças Retinianas/etiologia , Tomografia de Coerência Óptica , ÚteroRESUMO
PurposeTo analyze the macular structure in a large series of consecutive patients with different types of uveitis using spectral-domain optical coherence tomography (SD-OCT).Patients and methodsFive hundred eyes of 500 consecutive patients with anterior, intermediate, posterior, and panuveitis underwent standardized macular examination using SD-OCT. Central retinal thickness (CRT), macular volume (MV), and presence of cystoid macular edema (CME), diffuse macular edema (DME), serous retinal detachment (SRD), epiretinal membrane with (ERM+) and without (ERM-) retinal surface wrinkling were determined.ResultsThe anatomic location of inflammation affected significantly CRT and MV (P<0.001, respectively), with the highest values in intermediate and panuveitis. CME was seen in 25% of all uveitic eyes, DME in 11%, SRD in 8%, ERM+ in 18%, and ERM- in 13%. CME was most frequent in intermediate (40%) and panuveitis (36%); DME was most frequent in panuveitis (18%) and posterior uveitis (17%); SRD was most frequent in panuveitis (15%) and posterior uveitis (10%); ERM+ was most frequent in panuveitis (45%) and intermediate uveitis (30%); and ERM- was most frequent in intermediate (14%) and posterior uveitis (15%).ConclusionSD-OCT of the macula is recommended for all uveitis patients. CRT, MV, and the incidence of CME were highest in intermediate and panuveitis.
Assuntos
Membrana Epirretiniana/diagnóstico por imagem , Macula Lutea/diagnóstico por imagem , Edema Macular/diagnóstico por imagem , Descolamento Retiniano/diagnóstico por imagem , Tomografia de Coerência Óptica , Uveíte/diagnóstico por imagem , Adolescente , Adulto , Idade de Início , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Macula Lutea/patologia , Masculino , Pessoa de Meia-Idade , Uveíte/classificaçãoRESUMO
To our knowledge, we report the second instance of posterior urethral valves in identical twin boys. Initial symptoms, age at presentation and radiographic findings were different in each boy, and reflect the varying nature of this congenital anomaly. Although the brothers are identical twins from the same environment with identical Rh and ABO blood groupings and identical HLA haplotypes, developmental differences have been marked.
