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1.
Sci Rep ; 12(1): 2326, 2022 02 11.
Artigo em Inglês | MEDLINE | ID: mdl-35149706

RESUMO

Treatment recommendations for fragility fractures of the pelvis (FFP) have been provided along with the good reliable FFP classification but they are not proven in large studies and recent reports challenge these recommendations. Thus, we aimed to determine the usefulness of the FFP classification determining the treatment strategy and favored procedures in six level 1 trauma centers. Sixty cases of FFP were evaluated by six experienced pelvic surgeons, six inexperienced surgeons in training, and one surgeon trained by the originator of the FFP classification during three repeating sessions using computed tomography scans with multiplanar reconstruction. The intra-rater reliability and inter-rater reliability for therapeutic decisions (non-operative treatment vs. operative treatment) were moderate, with Fleiss kappa coefficients of 0.54 (95% confidence interval [CI] 0.44-0.62) and 0.42 (95% CI 0.34-0.49). We found a therapeutic disagreement predominantly for FFP II related to a preferred operative therapy for FFP II. Operative treated cases were generally treated with an anterior-posterior fixation. Despite the consensus on an anterior-posterior fixation, the chosen procedures are highly variable and most plausible based on the surgeon's preference.


Assuntos
Fraturas Ósseas/classificação , Fraturas Ósseas/terapia , Ossos Pélvicos/lesões , Tomografia Computadorizada por Raios X , Fraturas Ósseas/etiologia , Fraturas Ósseas/cirurgia , Fragilidade/complicações , Humanos , Ossos Pélvicos/cirurgia , Reprodutibilidade dos Testes
2.
J Orthop Translat ; 18: 92-99, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31508312

RESUMO

BACKGROUND: Common failure modes of dynamic hip screw are cut-out and lift-off. To minimize the latter, distal screws can be inserted in different orientations. However, the effectiveness remains controversial. The aim of this study was to biomechanically investigate the influence of distal screw orientation on construct stability. METHODS: Thirty artificial generic long bones were assigned to three groups (n = 10) and fixed with two-hole dynamic hip screw-plates, inserting distal cortical screws with neutral parallel screw orientation (A), divergent screw orientation (B) or convergent screw orientation (C). Starting at 60 N, cyclic loading was applied to the implant tip perpendicular to the lag screw axis with progressive peak load increase at a rate of 0.002 N/cycle until failure. Parameters of interest were construct stiffness and machine actuator displacement after 250, 1000 and 5000 cycles, as well as cycles to failure. RESULTS: Displacement after 250, 1000 and 5000 cycles was significantly higher in Group C than in Groups A and B, p < 0.01, whereas no significant differences were observed between Groups A and B, p = 0.20. Specimens in Group C failed after 11,584 [standard deviation (SD), 5924] cycles, significantly earlier than those in Groups A and B [A: 27,351 (SD, 12,509); B: 28,793 (SD, 14,764)], p ≤ 0.02. Cycles to failure were not significantly different between Groups A and B, p > 0.99. THE TRANSLATIONAL POTENTIAL OF THIS ARTICLE: Parallel or divergent distal screw insertion provides similar construct stability in terms of resistance to plate lift-off. In contrast, converging screw insertion leads to inferior stability and is not advisable from a biomechanical point of view.

3.
J Bone Joint Surg Am ; 101(11): 987-994, 2019 Jun 05.
Artigo em Inglês | MEDLINE | ID: mdl-31169575

RESUMO

BACKGROUND: The fragility fractures of the pelvis (FFP) classification was established to address the specific fracture morphology and dynamic instability in the elderly. Although this system is frequently used, data on the intra-rater and inter-rater reliabilities are lacking. METHODS: Six experienced and 6 inexperienced surgeons and 1 surgeon trained by the originator of the FFP classification ("gold standard") each used the FFP classification 3 times to grade the computed tomography (CT) scans of 60 patients from 6 hospitals. We assessed intra-rater and inter-rater reliabilities using Fleiss kappa statistics and the percentage of agreement using the "gold standard," the submitting hospital, and the majority vote as references. RESULTS: The intra-rater reliability for the FFP classification was mainly moderate, with a mean Fleiss kappa coefficient (and 95% confidence interval) of 0.46 (0.40 to 0.50) for the complete classification (i.e., both the main-group FFP ratings [I through III] and the subgroup ratings [a, b, and c]) and 0.60 (0.53 to 0.65) for the main group only. The inter-rater reliability was substantial for the main group classification (0.61 [0.54 to 0.66]) and moderate for the complete classification (0.53 [0.48 to 0.58]). The percentage of agreement was 68% to 80%. The lowest agreement was found for FFP II and III. CONCLUSIONS: The FFP classification displayed moderate and substantial intra-rater and inter-rater reliabilities. CLINICAL RELEVANCE: With moderate to substantial intra-rater and inter-rater reliabilities, the FFP classification forms a solid basis for future clinical investigations. The differentiation of FFP II from FFP III should be evaluated thoroughly, as the initial treatment changes from nonoperative for II to operative for III.


Assuntos
Fraturas do Quadril/classificação , Ossos Pélvicos/lesões , Idoso , Feminino , Humanos , Masculino , Variações Dependentes do Observador , Reprodutibilidade dos Testes
4.
J Hand Surg Eur Vol ; 44(7): 738-744, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31117866

RESUMO

Different multiplanar reformation (MPR-512 and -256) algorithms of intraoperative acquired 3-D-fluoroscopy data exist without recommendations for use in the literature. To compare algorithms, 3-D-fluoroscopic data sets of 46 radius fractures were blinded and processed using MPR-256 and -512 (Ziehm, Vision-Vario 3D). Each reformatted data set was analysed to evaluate image quality, fracture reduction quality and screw misplacements. Overall image quality was higher rated in the MPR-512 compared with the MPR-256 (3.2 vs. 2.2 points, scale 1-5 points), accompanied by a reduced number of scans that could not be analysed (10 vs. 19%). Interobserver evaluation of fracture reduction quality was fair to moderate (independent of the algorithm). In contrast, for screw misplacements MPR-depended ratings were found (MPR-256: fair to moderate; MPR-512: moderate to substantial). Optimization of post-processing algorithms, rather than modifications of image acquisition, may increase the image quality for assessing implant positioning, but limitations in evaluating fracture reduction quality still exist.


Assuntos
Algoritmos , Fixação de Fratura , Imageamento Tridimensional , Fraturas do Rádio/diagnóstico por imagem , Fraturas do Rádio/cirurgia , Cirurgia Assistida por Computador , Adulto , Idoso , Parafusos Ósseos , Estudos de Coortes , Feminino , Fluoroscopia , Humanos , Masculino , Pessoa de Meia-Idade
5.
Int Orthop ; 43(11): 2629-2636, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-30949757

RESUMO

PURPOSE: Pelvic ring fractures in the elderly gain increasing importance. Nonetheless, data on factors influencing treatment decision in relation to fracture classification, age, and the resulting treatment are still rare. METHODS: Prospectively collected data of the German Pelvic Injury Registry from patients aged over 65 years with a pelvic ring fracture were evaluated retrospectively. Acetabular fractures, as well as type A1 and A3 fractures, were excluded. The variables age, injury pattern, type of treatment, the reason for conservative treatment, and Orthopaedic Trauma Association (OTA)/Tile classification were analyzed. Furthermore, the fracture distribution was examined after dividing patients into six age groups. RESULTS: A total of 1814 patients with a mean age of 80.7 ± 7.6 years, predominantly female (79.0%), were available for evaluation. The majority of patients suffered from isolated pelvic ring fractures (70.1%) and 8.2% were severely injured (ISS > 16). The most common fracture types were type A2 (35.4%), type B2 (38.0%), and type C1 (7.3%). Especially pelvic ring fractures of type A2 (96.9%) and type B2 (83.0%) were treated conservatively (overall 76.9%). Fracture instability according to the OTA/Tile classification increased the probability for an operative treatment (generalized odds ratio [OR] 6.90 [5.62; 8.52]). In contrary, increasing age independent of the fracture pattern decreased this probability (OR 0.47 [0.41-0.53]). With increasing fracture instability, general health conditions were up to 50% of the reasons for conservative treatment. CONCLUSION: The results of the present study underline the importance of the factors age and general health besides fracture classification for therapeutic decision-making in the treatment of pelvic ring fractures in the elderly.


Assuntos
Tomada de Decisão Clínica , Tratamento Conservador , Fraturas Ósseas/terapia , Ossos Pélvicos/lesões , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Feminino , Fraturas Ósseas/classificação , Fraturas Ósseas/complicações , Fraturas Ósseas/cirurgia , Alemanha , Saúde , Humanos , Masculino , Traumatismo Múltiplo/complicações , Traumatismo Múltiplo/terapia , Ossos Pélvicos/cirurgia , Sistema de Registros , Estudos Retrospectivos , Resultado do Tratamento
6.
Case Rep Oncol ; 12(1): 22-28, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30792641

RESUMO

Infectious complications such as invasive aspergillosis or infection with Stenotrophomonas maltophilia (SM) in immunocompromised patients are associated with a high mortality rate. Our report concerns a 40-year-old male newly diagnosed very severe aplastic anemia (vSAA) who in consequence of a mosquito bite was suffering from skin lesion and consecutive soft tissue phlegmon subsequent to the administration of antithymocyte globulin; a full-thickness autologous meshed skin graft successfully performed to cover skin ulcera after allogeneic stem cell transplantation (SCT). This unusual case illustrates the importance of appropriate diagnosis, anti-infective therapy and close interdisciplinary diagnostic algorithms to minimalize side effects and the selection of resistant strains and to improve patients' outcome.

7.
APMIS ; 127(2): 53-63, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30698307

RESUMO

Assessment of bone graft material efficacy is difficult in humans, since invasive methods like staged CT scans or biopsies are ethically unjustifiable. Therefore, we developed a novel large animal model for the verification of a potential transformation of synthetic bone graft substitutes into vital bone. The model combines multiple imaging methods with corresponding histology in standardized critical sized cancellous bone defect. Cylindrical bone voids (10 ml) were created in the medial femoral condyles of both hind legs (first surgery at right hind leg, second surgery 3 months later at left hind leg) in three merino-wool sheep and either (i) left empty, filled with (ii) cancellous allograft bone or (iii) a synthetic, gentamicin eluting bone graft substitute. All samples were analysed with radiographs, MRI, µCT, DEXA and histology after sacrifice at 6 months. Unfilled defects only showed ingrowth of fibrous tissue, whereas good integration of the cancellous graft was seen in the allograft group. The bone graft substitute showed centripetal biodegradation and new trabecular bone formation in the periphery of the void as early as 3 months. µCT gave excellent insight into the structural changes within the defects, particularly progressive allograft incorporation and the bone graft substitute biodegradation process. MRI completed the picture by clearly visualizing soft tissue ingrowth into unfilled bone voids and presence of fluid collections. Histology was essential for verification of trabecular bone and osteoid formation. Conventional radiographs and DEXA could not differentiate details of the ongoing transformation process. This model appears well suited for detailed in vivo and ex vivo evaluation of bone graft substitute behaviour within large bone defects.


Assuntos
Substitutos Ósseos/uso terapêutico , Transplante Ósseo/métodos , Osso Esponjoso/crescimento & desenvolvimento , Fêmur/cirurgia , Aloenxertos , Animais , Sulfato de Cálcio , Durapatita , Feminino , Imageamento por Ressonância Magnética , Modelos Animais , Ovinos
8.
J Orthop Res ; 37(3): 689-696, 2019 03.
Artigo em Inglês | MEDLINE | ID: mdl-30537046

RESUMO

(1) Can iliosacral osseous corridor diameters in sacral dysmorphism be enlarged by in-out-in screw placement at the posterior iliosacral recessus? (2) Are lumbosacral transitional vertebra (LSTV) the anatomical cause for sacral dysmorphism? (3) Are there sex-specific differences in sacral dysmorphism? 594 multislice CT scans were screened for sacral dysmorphism and 55 data-sets selected. Each pelvis was segmented manually and cylindrical iliosacral corridors (on the level of S1 and S2 vertebra) were semi-automatically determined. Corridor trajectories, -diameters and -lengths were measured. LSTV (Castellvi-type IIIb and IV) were found in 3 of 55 pelves and these lumbosacral variations are therefore not the anatomical basis for sacral dysmorphism. The prevalence of transsacral osseous corridors with diameters of <7.5 mm in axial CT images correlates with qualitative and quantitative criteria of sacral dysmorphism. Enlarging the osseous corridor diameters by penetration of the posterior iliosacral recessus increase the safe corridor diameters (females versus males) by 26% versus 15% at the level of S1- and 50% versus 48% at the level of S2-vertebra. Sex-specific differences for both corridors (osseous and in-out-in) were only found for the osseous corridor diameters at the level of S1 vertebra, being smaller in females (females versus males: 13.3 ± 3.6 mm versus 15.5 ± 3.8 mm, p = 0.04). Dysmorphic sacra can be reliably detected on standard axial CT slice images. Modified in-out-in corridors on the level of S1-vertebra allow screw placement in all patients, but is still demanding compared to non-dysmorphic sacra, due to the oblique corridor axis. Recommendations for intraoperative orientation for oblique screw placement are defined. © 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res.


Assuntos
Variação Anatômica , Sacro/anormalidades , Sacro/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Parafusos Ósseos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Ortopédicos , Valores de Referência , Caracteres Sexuais , Adulto Jovem
9.
BMC Musculoskelet Disord ; 19(1): 168, 2018 May 24.
Artigo em Inglês | MEDLINE | ID: mdl-29793458

RESUMO

BACKGROUND: Autologous chondrocyte implantation (ACI) is a therapy for articular cartilage and osteochondral lesions that relies on notch- or trochlea-derived primary chondrocytes. An alternative cell source for ACI could be osteochondritis dissecans (OCD) fragment-derived chondrocytes. Assessing the potential of these cells, we investigated their characteristics ex vivo and after monolayer expansion, as monolayer expansion is an integral step of ACI. However, as monolayer expansion can induce de-differentiation, we asked whether monolayer-induced de-differentiation can be reverted through successive alginate bead culture. METHODS: Chondrocytes were isolated from the OCD fragments of 15 patient knees with ICRS grades 3-4 lesions for ex vivo analyses, primary alginate bead culture, monolayer expansion, and alginate bead culture following monolayer expansion for attempting re-differentiation. We determined yield, viability, and the mRNA expression of aggrecan and type I, II, and X collagen. RESULTS: OCD fragment-derived chondrocyte isolation yielded high numbers of viable cells with a low type I:II collagen expression ratio (< 1) and a relatively high aggrecan and type II and X collagen mRNA expression, indicating chondrogenic and hypertrophic characteristics. As expected, monolayer expansion induced de-differentiation. Alginate bead culture of monolayer-expanded cells significantly improved the expression profile of all genes investigated, being most successful in decreasing the hypertrophy marker type X collagen to 1.5% of its ex vivo value. However, the chondrogenic phenotype was not fully restored, as the collagen type I:II expression ratio decreased significantly but remained > 1. CONCLUSION: OCD fragment derived human chondrocytes may hold not yet utilized clinical potential for cartilage repair.


Assuntos
Alginatos/administração & dosagem , Desdiferenciação Celular/fisiologia , Diferenciação Celular/fisiologia , Condrócitos/patologia , Condrócitos/fisiologia , Osteocondrite Dissecante/patologia , Adolescente , Adulto , Cartilagem Articular/efeitos dos fármacos , Cartilagem Articular/patologia , Cartilagem Articular/fisiologia , Técnicas de Cultura de Células/métodos , Desdiferenciação Celular/efeitos dos fármacos , Diferenciação Celular/efeitos dos fármacos , Células Cultivadas , Condrócitos/efeitos dos fármacos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Osteocondrite Dissecante/diagnóstico por imagem , Adulto Jovem
10.
Foot Ankle Surg ; 23(4): 250-254, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29202983

RESUMO

BACKGROUND: Collapse of the medial longitudinal arch and subluxation of the subtalar joint are common occurrences in adult flatfoot deformity. Controversy exists about the role of the tibialis posterior (TP) tendon as first and/or essential lesion. Subtle changes in the foot configuration can occur under weight bearing. PURPOSE: This human cadaveric study is designed to investigate the effect that isolated actuation of the TP tendon has on the medial longitudinal arch and the hindfoot configuration under simulated weight bearing. METHODS: A radiolucent frame was developed to apply axial loading on cadaveric lower legs during computer tomography (CT) examinations. Eight pairs of fresh-frozen specimens were imaged in neutral position under foot-flat loading (75N) and under single-leg stance weight bearing (700N) without and with addition of 150N pulling force on the TP tendon. Measurements of subtalar joint subluxation, forefoot arch angle and talo-first metatarsal angle were conducted on each set of CT scans. RESULTS: Subtalar subluxation, talo-first metatarsal angle and talo-navicular coverage angle significantly increased under single-leg stance weight bearing, whereas forefoot arch angle significantly decreased. Actuation of the TP tendon under weight bearing did not restore the forefoot arch angle or correct subtalar subluxation and talo-metatarsal angle. CONCLUSION: Significant effect that weight bearing has on the medial longitudinal arch and the subtalar joint configuration is demonstrated in an ex-vivo model. In absence of other medial column derangement, actuation of the TP tendon alone does not seem to reconstitute the integrity of the medial longitudinal arch or correct the hindfoot subluxation under weight bearing. CLINICAL RELEVANCE: The findings of this study together with the developed model for ex-vivo investigation provide a further insight in foot anatomy.


Assuntos
Articulações do Pé/fisiopatologia , Pé/diagnóstico por imagem , Pé/fisiopatologia , Luxações Articulares/fisiopatologia , Contração Muscular/fisiologia , Músculo Esquelético/fisiopatologia , Fenômenos Biomecânicos , Cadáver , Pé/anatomia & histologia , Deformidades Adquiridas do Pé/diagnóstico por imagem , Deformidades Adquiridas do Pé/fisiopatologia , Articulações do Pé/diagnóstico por imagem , Humanos , Luxações Articulares/diagnóstico por imagem , Músculo Esquelético/diagnóstico por imagem , Disfunção do Tendão Tibial Posterior/diagnóstico por imagem , Disfunção do Tendão Tibial Posterior/fisiopatologia , Estresse Mecânico , Tomografia Computadorizada por Raios X , Suporte de Carga/fisiologia
11.
J Orthop Trauma ; 31(7): e210-e216, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28240619

RESUMO

OBJECTIVES: Anatomical acetabular plates the anterior intrapelvic approach (AIP) were recently introduced to fix acetabular fractures through the intrapelvic approach. Therefore, we asked the following: (1) Does the preshaped 3-dimensional suprapectineal plate interfere with or even impair the fracture reduction quality? (2) How often does the AIP approach need to be extended by the first (lateral) window of the ilioinguinal approach? DESIGN: Observational case series. SETTING: Two Level 1 trauma centers. PATIENTS/PARTICIPANTS: Patients with unstable acetabular fractures in 2014. INTERVENTION: Fracture fixation with anatomical-preshaped, 3-dimensional suprapectineal plates through the AIP approach ± the first window of the ilioinguinal approach. OUTCOME MEASUREMENTS: Fracture reduction results were measured in computed tomography scans and graded according to the Matta quality of reduction. Intraoperative parameters and perioperative complications were recorded. Radiological results (according to Matta) and functional outcome (modified Merle d'Aubigné score) were evaluated at 1-year follow-up. RESULTS: Thirty patients (9 women + 21 men; mean age ± SE: 64 ± 8 years) were included. The intrapelvic approach was solely used in 19 cases, and in 11 cases, an additional extension with the first window of the ilioinguinal approach (preferential for 2-column fractures) was performed. The mean operating time was 202 ± 59 minutes; the fluoroscopic time was 66 ± 48 seconds. Fracture gaps and steps in preoperative versus postoperative computed tomography scans were 12.4 ± 9.8 versus 2.0 ± 1.5 and 6.0 ± 5.5 versus 1.3 ± 1.7 mm, respectively. At 13.4 ± 2.9 months follow-up, the Matta grading was excellent in 50%, good in 25%, fair in 11%, and poor in 14% of cases. The modified Merle d'Aubigné score was excellent in 17%, good in 37%, fair in 33%, and poor in 13% of cases. CONCLUSION: The AIP approach using approach-specific instruments and an anatomical-preshaped, 3-dimensional suprapectineal plate became the standard procedure in our departments. Radiological and functional early results justify joint preserving surgery in most cases. LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Acetábulo/lesões , Placas Ósseas , Fixação Interna de Fraturas/instrumentação , Fraturas Ósseas/cirurgia , Idoso , Desenho de Equipamento , Feminino , Fixação Interna de Fraturas/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Duração da Cirurgia , Resultado do Tratamento
12.
J Orthop Trauma ; 31(3): 131-137, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-27755333

RESUMO

OBJECTIVES: To evaluate the biomechanical performance of femoral neck system (FNS) in comparison with established methods for fixation of femoral neck fractures in a cadaveric model. METHODS: Twenty pairs of fresh-frozen human cadaveric femora were instrumented either with dynamic hip screw and antirotation screw (DHS-screw), DHS-blade, 3 cannulated screws (3CS) or with FNS in a partially paired design. The specimens were randomized to 2 paired treatment groups based on the bone mineral density (BMD), namely DHS-screw/DHS-blade and FNS/3CS. A reduced unstable femoral neck fracture with postero-caudal comminution, OTA/AO 31-B2.3, 70 degrees Pauwels III, was simulated by cutting 30 degrees distal and 15 degrees posterior wedges. Cyclic axial loading was applied in 16 degrees adduction, starting at 500 N and with progressive peak force increase of 0.1 N/cycle until construct failure. Axial stiffness was measured in the third loading cycle. Femoral neck and leg shortening, and varus tilting and implant migration were calculated by means of optical motion tracking. RESULTS: Mean axial stiffness was 688.8 ± 132.6 N/mm for DHS-screw, 629.1 ± 94.1 N/mm for DHS-blade, 748.9 ± 211.4 N/mm for FNS, and 584.1 ± 156.6 N/mm for 3CS, with no statistical significances. Cycles until 15-mm leg shortening were comparable for DHS-Screw (20,542 ± 7465), DHS-blade (19,161 ± 3793) and FNS (17,372 ± 2996), however significantly higher than for 3CS (7293 ± 2819), P < 0.001. Similarly, cycles until 15 mm femoral neck shortening were comparable between DHS-screw (20,846 ± 7339), DHS-blade (18,974 ± 4032) and FNS (18,171 ± 2585), and significantly higher than 3CS (8039 ± 2778), P < 0.001. CONCLUSIONS: From a biomechanical point of view, the femoral neck system is a valid alternative to treat unstable femoral neck fractures, representing the advantages of a minimally invasive implant with comparable stability to the 2 DHS systems and superior to cannulated screws.


Assuntos
Parafusos Ósseos/estatística & dados numéricos , Fraturas do Colo Femoral/fisiopatologia , Fraturas do Colo Femoral/cirurgia , Fixação Interna de Fraturas/instrumentação , Fraturas Mal-Unidas/fisiopatologia , Fraturas Mal-Unidas/cirurgia , Idoso , Parafusos Ósseos/classificação , Cadáver , Módulo de Elasticidade , Análise de Falha de Equipamento , Feminino , Fixação Interna de Fraturas/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Desenho de Prótese , Estatística como Assunto , Resistência à Tração
13.
Clin Orthop Relat Res ; 474(10): 2304-11, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-27392768

RESUMO

BACKGROUND: Percutaneous iliosacral screw placement is the standard procedure for fixation of posterior pelvic ring lesions, although a transsacral screw path is being used more frequently in recent years owing to increased fracture-fixation strength and better ability to fix central and bilateral sacral fractures. However, biomorphometric data for the osseous corridors are limited. Because placement of these screws in a safe and effective manner is crucial to using transsacral screws, we sought to address precise sacral anatomy in more detail to look for anatomic variation in the general population. QUESTIONS/PURPOSES: We asked: (1) What proportion of healthy pelvis specimens have no transsacral corridor at the level of the S1 vertebra owing to sacral dysmorphism? (2) If there is no safe diameter for screw placement in the transsacral S1 corridor, is an increased and thus safe diameter of the transsacral S2 corridor expected? (3) Are there sex-specific differences in sacral anatomy and are these correlated with known anthropometric parameters? METHODS: CT scans of pelves of 280 healthy patients acquired exclusively for medical indications such as polytrauma (20%), CT angiography (70%), and other reasons (10%), were segmented manually. Using an advanced CT-based image analysis system, the mean shape of all segmented pelves was generated and functioned as a template. On this template, the cylindric transsacral osseous corridor at the level of the S1 and S2 vertebrae was determined manually. Each pelvis then was registered to the template using a free-form registration algorithm to measure the maximum screw corridor diameters on each specimen semiautomatically. RESULTS: Thirty of 280 pelves (11%) had no transsacral S1 corridor owing to sacral dysmorphism. The average of maximum cylindrical diameters of the S1 corridor for the remaining 250 pelves was 12.8 mm (95% CI, 12.1-13.5 mm). A transverse corridor for S2 was found in 279 of 280 pelves, with an average of maximum cylindrical diameter of 11.6 mm (95% CI, 11.3-11.9 mm). Decreasing transsacral S1 corridor diameters are correlated with increasing transsacral S2 corridor diameters (R value for females, -0.260, p < 0.01; for males, -0.311, p < 0.001). Female specimens were more likely to have sacral dysmorphism (defined as a pelvis without a transsacral osseous corridor at the level of the S1 vertebra) than were male specimens (females, 16%; males, 7%; p < 0.003). Furthermore female pelves had smaller-corridor diameters than did male pelves (females versus males for S1: 11.7 mm [95% CI, 10.6-12.8 mm] versus 13.5 mm [95% CI, 12.6-14.4 mm], p < 0.01; and for S2: 10.6 mm [95% CI, 10.1-11.1 mm] versus 12.2 mm [95% CI, 11.8-12.6 mm ], p < 0.0001). CONCLUSIONS: Narrow corridors and highly individual, sex-dependent variance of morphologic features of the sacrum make transsacral implant placement technically demanding. Individual preoperative axial-slice CT scan analyses and orthogonal coronal and sagittal reformations are recommended to determine the prevalence of sufficient-sized osseous corridors on both levels for safe screw placements, especially in female patients, owing to their smaller corridor diameters and higher rate of sacral dysmorphism.


Assuntos
Parafusos Ósseos , Procedimentos Ortopédicos/instrumentação , Ossos Pélvicos/diagnóstico por imagem , Ossos Pélvicos/cirurgia , Tomografia Computadorizada por Raios X , Adulto , Idoso , Idoso de 80 Anos ou mais , Pontos de Referência Anatômicos , Feminino , Voluntários Saudáveis , Humanos , Ílio/anormalidades , Ílio/diagnóstico por imagem , Ílio/cirurgia , Masculino , Pessoa de Meia-Idade , Procedimentos Ortopédicos/efeitos adversos , Ossos Pélvicos/anormalidades , Valor Preditivo dos Testes , Interpretação de Imagem Radiográfica Assistida por Computador , Sacro/anormalidades , Sacro/diagnóstico por imagem , Sacro/cirurgia , Caracteres Sexuais , Fatores Sexuais , Adulto Jovem
14.
Int Orthop ; 40(7): 1537-43, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-26435263

RESUMO

INTRODUCTION: Treatment of posterior pelvic ring injuries is frequently associated with pain or/and high mortality rates. Percutaneous sacro-iliac (SI) screw fixation has proved to be one of the methods of choice, providing minimal operative time, blood loss and wound-related morbidity. However, fixation failures due to secondary fracture dislocation or screw backing out have been reported. There is a little knowledge regarding the impact of varying screw orientation and quality of reduction on the fixation strength. PURPOSE: The purpose of the present study was biomechanical investigation of joint stability after SI screw fixation and its dependence on quality of reduction and screw orientation. METHODS: Thirty-two artificial hemi-pelvices were assigned to four study groups and simulated SI dislocations were fixed with two SI screws in oblique or transverse screw orientation and anatomical or non-anatomical reduction in group A (oblique/anatomical), B (transverse/anatomical), C (oblique/non-anatomical) and D (transverse/non-anatomical). Mechanical testing was performed under progressively increasing cyclic axial loading until fixation failure. SI joint movements were captured via optical motion tracking. Fixation performance was statistically evaluated at a level of significance p = 0.05. RESULTS: The highest cycles to failure were observed in group A (14038 ± 1057), followed by B (13909 ± 1217), D (6936 ± 1654) and C (6706 ± 1295). Groups A and B revealed significantly longer endurance than C and D (p ≤ 0.01). CONCLUSIONS: Different screw orientations in the presented model do not influence substantially SI joint stability. However, anatomical reduction is not only mandatory to restore a malalignment, but also to increase the SI screw fixation strength and prevent fixation failures.


Assuntos
Parafusos Ósseos/efeitos adversos , Fixação Interna de Fraturas/métodos , Luxações Articulares/fisiopatologia , Articulação Sacroilíaca/cirurgia , Fenômenos Biomecânicos , Cadáver , Humanos , Luxações Articulares/cirurgia , Articulação Sacroilíaca/lesões
15.
BMC Musculoskelet Disord ; 16: 238, 2015 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-26338080

RESUMO

BACKGROUND: The coracoacromial ligament (CAL) is an important restraint to superior shoulder translation. CAL release with the Latarjet procedure leads to increased superior humeral translation. Therefore, a surgical technique was developed to reconstruct the CAL during a modified Latarjet procedure. METHODS: Between May 2010 and July 2011, six patients (five were male, one was female; age 23-41 years) with chronic post-traumatic anterior shoulder instability were treated surgically with a modified congruent-arc Latarjet procedure (modLAT) with additional reconstruction of the CAL using a newly developed procedure, the pectoralis minor fascia flap (PMFF). Clinical follow-up was performed for up to 36 months, and patients were evaluated using a Rowe score. RESULTS: All six patients experienced chronic, post-traumatic anterior shoulder instability and had experienced multiple re-dislocations after initial treatment. The preoperative assessment showed a defect of the anterior glenoid in three cases, and the mean Rowe score was 16.67 (5-25). Open modLAT with PMFF resulted in a stable shoulder function with no re-dislocations. The Rowe score increased from 77.5 (65-90) at 12 weeks to 95 (90-100) at 12 months and plateaued thereafter. Operative duration was 95 min (78-112 min), and there were no intra- or postoperative complications. All patients returned to their preoperative sports activity, three at the same level. CONCLUSION: The PMFF is a safe technique for reconstruction of the CAL during a modLAT procedure. Patients had improved shoulder function and no re-dislocations after the surgery.


Assuntos
Ligamentos Articulares/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Luxação do Ombro/diagnóstico , Luxação do Ombro/cirurgia , Articulação do Ombro/cirurgia , Adulto , Feminino , Humanos , Instabilidade Articular/diagnóstico , Instabilidade Articular/cirurgia , Ligamentos Articulares/patologia , Masculino , Articulação do Ombro/patologia , Adulto Jovem
16.
Foot Ankle Surg ; 21(2): 113-8, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25937411

RESUMO

BACKGROUND: The distal soft tissue procedure is an integral part of hallux valgus surgery, providing soft tissue balance and alignment restoration of the first metatarsophalangeal joint. Various approaches have been established to this end. For techniques that do not include a separate dorsal incision, lateral release may be achieved via a transarticular approach or via a medial incision and a dorsal flap over the first metatarsal. Compared to the double-incision technique, these techniques are not only cosmetically superior and thus meet the demands of most surgeons and patients. MATERIAL AND METHODS: Using six pairs of frozen cadaveric feet, lateral release was performed using one of the above techniques in a randomized manner with pair comparison. The specimens were then dissected and the completeness of the release as well as any damage to anatomic structures was documented. RESULTS: The transarticular technique enabled complete release of the metatarsal-sesamoid suspensory ligament (MSL) and the transverse and oblique head of the adductor hallucis muscle in five of six specimens. The comparative technique enabled the same in only two of six cases for the adductor hallucis muscle and in four cases for the MSL. The transarticular approach achieved complete release of the lateral joint capsule in three of six specimens, whereas the dorsal approach achieved no release in any specimen. Neither of the methods caused any macroscopic injury to the surfaces of the first metatarsophalangeal joint. The examined arteries, veins, and nerves remained intact in all specimens treated with the transarticular approach, but dorsal release resulted in one documented injury to the first dorsal metatarsal artery and its concomitant veins. CONCLUSIONS: Compared to release by dissection superficially to the extensor tendons, transarticular release provides a more complete lateral release and less injuries to neurovascular bundles. Further anatomic and clinical studies are needed, however, before conclusive recommendations can be made.


Assuntos
Pé/cirurgia , Hallux Valgus/cirurgia , Idoso , Idoso de 80 Anos ou mais , Cadáver , Dissecação , Feminino , Pé/anatomia & histologia , Humanos , Cápsula Articular/cirurgia , Ligamentos Articulares/cirurgia , Articulação Metatarsofalângica/cirurgia , Músculo Esquelético/cirurgia
17.
J Foot Ankle Surg ; 54(5): 787-92, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25746771

RESUMO

Fusion of the first tarsometatarsal joint is a widely used procedure for the correction of hallux valgus deformity. Although dorsomedial H-shaped plating systems are being increasingly used, fusion can also be achieved by plantar plating. The goal of the present study was to compare these 2 operative techniques based on the anatomic considerations and show the potential pitfalls of both procedures. Six pairs of deep-frozen human lower legs were used in the present cadaveric study. In a randomized manner, either dorsomedial arthrodesis or plantar plating through a medial incision was performed. With regard to arterial injury, the plantar technique resulted in fewer lesions (plantar, 4 injuries [66.7%] to the terminal branches of the first digital branch of the medial plantar artery; dorsomedial, 3 injuries [50%] to the main trunks of the plantar metatarsal arteries and the first dorsal metatarsal artery). With respect to injury to the veins, the plantar procedure affected significantly fewer high-caliber subcutaneous trunk veins. The nerves coursing through the operative field, such as the saphenous and superficial fibular nerves, were compromised more often by the dorsal approach. Neither the plantar plating nor the dorsomedial plating technique was associated with injury to the insertion of the tibialis anterior muscle. Both studied techniques are safe, well-established procedures. Arthrodesis with plantar plating, however, offers additional advantages and is a reliable tool in the foot and ankle surgeon's repertoire.


Assuntos
Artrodese/instrumentação , Artrodese/métodos , Placas Ósseas , Hallux Valgus/cirurgia , Idoso , Idoso de 80 Anos ou mais , Fenômenos Biomecânicos , Cadáver , Dissecação , Feminino , Humanos , Masculino , Ossos do Metatarso/cirurgia , Ossos do Tarso/cirurgia
18.
Clin Orthop Relat Res ; 473(1): 361-9, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25261258

RESUMO

BACKGROUND: An infraacetabular screw path facilitates the closure of a periacetabular fixation frame to increase the plate fixation strength in acetabular fractures up to 50%. Knowledge of the variance in corridor sizes and axes has substantial surgical relevance for safe screw placement. QUESTIONS/PURPOSES: (1) What proportion of healthy pelvis specimens have an infraacetabular corridor that is 5 mm or larger in diameter? (2) Does a universal corridor axis and specific screw entry point exist? (3) Are there sex-specific differences in the infraacetabular corridor size or axis and are these correlated with anthropometric parameters like age, body weight and height, or the acetabular diameter? METHODS: A template pelvis with a mean shape from 523 segmented pelvis specimens was generated using a CT-based advanced image analyzing system. Each individual pelvis was registered to the template using a free-form registration algorithm. Feasible surface regions for the entry and exit points of the infraacetabular corridor were marked on the template and automatically mapped to the individual samples to perform a measurement of the maximum sizes and axes of the infraacetabular corridor on each specimen. A minimum corridor diameter of at least 5 mm was defined as a cutoff for placing a 3.5-mm cortical screw in clinical settings. RESULTS: In 484 of 523 pelves (93%), an infraacetabular corridor with a diameter of at least 5 mm was found. Using the mean axis angulations (54.8° [95% confidence interval {CI}, 0.6] from anterocranial to posterocaudal in relation to the anterior pelvic plane and 1.5° [95% CI, 0.4] from anteromedial to posterolateral in relation to the sagittal midline plane), a sufficient osseous corridor was present in 64% of pelves. Allowing adjustment of the three-dimensional axis by another 5° included an additional 25% of pelves. All corridor parameters were different between females and males (corridor diameter, 6.9 [95% CI, 0.2] versus 7.7 [95% CI, 0.2] mm; p<0.001; corridor length, 96.2 [95% CI, 0.7] versus 106.4 [95% CI, 0.6] mm; p<0.001; anterior pelvic plane angle, 54.0° [95% CI, 0.9] versus 55.3° [95% CI, 0.8]; p<0.01; sagittal midline plane angle, 4.3° [95% CI, 0.6] versus -0.3° [95% CI, 0.5]; p<0.001). CONCLUSION: This study provided reference values for placement of a 3.5-mm cortical screw in the infraacetabular osseous corridor in 90% of female and 94% of male pelves. Based on the sex-related differences in corridor axes, the mean screw trajectory is approximately parallel to the sagittal midline plane in males but has to be tilted from medial to lateral in females. Considering the narrow corridor diameters, we suggest an individual preoperative CT scan analysis for fine adjustments in each patient.


Assuntos
Acetábulo/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Acetábulo/lesões , Acetábulo/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Algoritmos , Parafusos Ósseos , Bases de Dados Factuais , Feminino , Fixação Interna de Fraturas/instrumentação , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Interpretação de Imagem Radiográfica Assistida por Computador , Sistemas de Informação em Radiologia , Fatores Sexuais , Cirurgia Assistida por Computador , Adulto Jovem
19.
J Orthop Res ; 33(2): 254-60, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25408471

RESUMO

It is hypothesized that ilio-sacro-iliacal corridors for a new envisioned pelvic ring implant (trans-sacral nail with two iliacal bolts = ISI-nail: ilio-sacro-iliacal nail) exists on the level of S1- or S2-vertebra in each patient. The corridors of 84 healthy human pelves (42x ♂; 42x ♀, 18-85 years) were measured in high resolution CT scans using the Merlin Diagnostic Workcenter Software. Trans-sacral corridors (≥ 9 mm diameter) on the level of S1 and S2 were found in 62% and 54% of pelves with a mean length [mm ± SD] of 164 ± 12.9 and 142 ± 10.2. Corresponding iliac corridors were present in all specimens in caudally tilted axial planes of 37.8 ± 0.67° and 53.7 ± 0.94° in relation to the operating table plane and divergent angulations of 69.0 ± 0.49° and 70.1 ± 0.32° in relation to the sagittal midline plane. Sacral dysmorphism, with compensatory larger S2 corridors were prevalent in 24% of pelves; ilio-sacro-iliacal osseous corridors for the envisioned implant were found in 88% of pelves on the level of S1 or S2. In the remaining 12% with too narrow corridors for any trans-sacral implant (screws, bars, ISI nail) alternative fixation methods have to be considered. Expected advantages of the envisioned ISI nail compared to available fixation devices are discussed.


Assuntos
Ossos Pélvicos/diagnóstico por imagem , Sacro/diagnóstico por imagem , Adolescente , Adulto , Idoso , Antropometria , Feminino , Fixação de Fratura , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , Valores de Referência , Adulto Jovem
20.
Orthop Rev (Pavia) ; 6(4): 5611, 2014 Oct 27.
Artigo em Inglês | MEDLINE | ID: mdl-25568732

RESUMO

Osteoarthritis (OA) is more common in the knee compared to the ankle joint. This can not be explained exclusively by anatomical and biomechanical differences. The aim of this study is to analyze and compare the injury pattern (clinically) and the cartilage lesions (arthroscopically) of knee and ankle joints in a cohort of patients from the same catchment area. A retrospective study of the clinical data of 3122 patients (2139 outpatients and 983 inpatients) was performed, who were treated due to an injury of the knee and ankle joint. Statistical analysis was performed using SigmaStat 3.0 (SPSS Inc, Chicago, USA). There is a higher prevalence of injuries in the ankle as compared to the knee joint in this population from the same catchment area. In contrast, high-grade cartilage lesions are more prevalent in the knee, whereas low grade cartilage lesions are equally distributed between knee and ankle. From this data it can be concluded that the frequency of injuries and the injury pattern of knee versus ankle joints do not correlate with the severity of cartilage lesions and may therefore have no direct influence on the differential incidence of OA in those two joints.

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