[Thrombolytic therapy: formation and current practice of intravenous thrombolysis in acute ischemic stroke].

The benefits and limitations of intravenous thrombolytic therapy using recombinant tissue plasminogen activator (alteplase) are discussed. Pathophysiological background of thrombolysis, its history and ways of clinical usage, the major clinical trials, assessing safety and efficacy of the method, and practical recommendations, are presented.

[Metabolism macroergic compounds in erythrocytes in the initial forms of cerebrovascular diseases]. / Metabolizm makroérgicheskikh soedinenii v éritrotsitakh pri nachal'nykh formakh sosudistykh zabolevanii golovnogo mozga.

The spectra of 31P-NMR erythrocytes in patients with initial symptoms of cerebral circulation insufficiency compared to blood-donors were analysed. The expansion of 31P-NMR ATP and 2,3-DPG signals is observed in pathology. On these grounds the authors have come to a conclusion that the population of erythrocytes is more heterogeneous as to oxygen saturation than in normal state.