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1.
Future Hosp J ; 1(1): 23-25, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31098040

RESUMO

The benefits of specialist geriatric assessment in acute medical units are debated and it is unclear if there is a reduction in readmission rates for older patients with specialist geriatric care compared to general acute medical care. We examined readmission rates for 2414 older patients who had been discharged from the acute medical unit at the Norfolk and Norwich University Hospital, either by acute medicine or older people's medicine (OPM), both of which teams were consultant-led. We found no significant difference in readmission rates between patients discharged by the acute medical team as compared to the OPM team. This finding was robust to a variety of sensitivity analyses, including different lengths of stay, or readmissions at different time intervals. Hence, acute medical teams may be able to achieve similar levels of quality care for older patients to specialist geriatric teams.

2.
Diabetologia ; 55(3): 795-800, 2012 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22193513

RESUMO

AIMS/HYPOTHESIS: The aim of this study was to determine the influence of microvascular disease on C-fibre function in patients with type 1 diabetes of moderate duration. METHODS: The axon-reflex flare area induced on the dorsum of the foot by local skin heating to 47 °C was measured with a laser Doppler imager (LDI) in sex-, age- and height-matched groups with type 1 diabetes, with and without microvascular disease (MV+ and MV-, respectively) and in healthy controls (HC). Each group consisted of 24 individuals and all were free from clinical neuropathy (neuropathy disability score <3 and Toronto clinical neuropathy score <5). RESULTS: LDI flare (LDIflare) was reduced in MV+ compared with HC (5.1 ± 1.8 vs 10.0 ± 3.1 cm², p < 0.0001) and MV- groups (9.9 ± 2.9 cm², p < 0.0001). MV- and HC groups did not differ. There was no difference in diabetes duration between MV- and MV+ groups (17.5 ± 5.7 and 20.1 ± 5.2 years, p = 0.21) nor current HbA(1c) (MV- 8.0 ± 1.2% [64 ± 10 mmol/mol]; MV+ 8.0 ± 0.9% [64 ± 9 mmol/mol], p = 0.53); neither variable correlated with flare size. In contrast, duration-averaged HbA(1c) was higher in the MV+ group (8.6 ± 0.9% [70 ± 9 mmol/mol] vs 7.6 ± 0.6% [60 ± 7 mmol/mol], p < 0.001) and correlated with LDIflare size (r = -0.50, p < 0.001). Triacylglycerols were higher in MV+ compared with MV- (1.23 ± 0.121 vs 0.93 ± 0.7 mmol/l, p = 0.04), but other metabolic variables did not differ between the groups. CONCLUSIONS/INTERPRETATION: We have shown that glycaemic burden and the presence of microvascular complications are associated with small fibre dysfunction in type 1 diabetes.


Assuntos
Diabetes Mellitus Tipo 1/complicações , Angiopatias Diabéticas/fisiopatologia , Neuropatias Diabéticas/fisiopatologia , Hiperglicemia/prevenção & controle , Microvasos/fisiopatologia , Fibras Nervosas/patologia , Nervos Periféricos/fisiopatologia , Adulto , Estudos de Casos e Controles , Estudos de Coortes , Diabetes Mellitus Tipo 1/sangue , Neuropatias Diabéticas/diagnóstico por imagem , Neuropatias Diabéticas/patologia , Diagnóstico Precoce , Feminino , , Hemoglobinas Glicadas/análise , Humanos , Hipertrigliceridemia/complicações , Masculino , Pessoa de Meia-Idade , Fibras Nervosas/diagnóstico por imagem , Nervos Periféricos/diagnóstico por imagem , Índice de Gravidade de Doença , Pele/inervação , Ultrassonografia
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