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Probl Radiac Med Radiobiol ; 23: 481-489, 2018 Dec.
Artigo em Inglês, Ucraniano | MEDLINE | ID: mdl-30582865

RESUMO

OBJECTIVE: evaluate the retinal morphometric parameters of the reconvalescents in remote period after acute radi-ation sickness. MATERIALS AND METHODS: A complete ophthalmologic examination was carried out on 7 reconvalescents of acuteradiation sickness. The examined are divided into two subgroups: 1) patients with macular degeneration of the reti-na (8 eyes); 2) patients without clinical signs of macular pathology (6 eyes). Parameters of the retina in the cen-tral retina zone studied using the method of optical coherence tomography. To evaluate the results of surveys usedstatistical methods: average values of quantitative indicators calculation, estimation of probability difference byStudent's method. RESULTS: Optical coherence tomography revealed a statistically significant increase of the thickness of the retina inthe fovea in all reconvalescents of acute radiation sickness. CONCLUSIONS: It was shown that the thickness of the retina in the fovea and paramacular zone in persons who suf-fered acute radiation sickness is significantly higher than in the control. These changes observed in all reconvalis-cents ARS - both in person with sings of macular degeneration, and in those whose clinical manifestations were notdetected. The presence of a correlation between the volume of the retina in the macular zone and the documentedradiation dose of the study group emphasizes the perspectives of next OCT examination of the retina of reconvales-cents of ARS to study the mechanism of retina's damage in this category of victims of the Chornobyl accident.


Assuntos
Acidente Nuclear de Chernobyl , Exposição Ambiental/efeitos adversos , Fóvea Central/patologia , Degeneração Macular/patologia , Exposição à Radiação/efeitos adversos , Lesões por Radiação/patologia , Doença Aguda , Idoso , Idoso de 80 Anos ou mais , Convalescença , Exposição Ambiental/análise , Feminino , Fóvea Central/diagnóstico por imagem , Humanos , Estudos Longitudinais , Degeneração Macular/diagnóstico por imagem , Degeneração Macular/etiologia , Masculino , Pessoa de Meia-Idade , Doses de Radiação , Exposição à Radiação/análise , Lesões por Radiação/diagnóstico por imagem , Lesões por Radiação/etiologia , Radiação Ionizante , Tomografia de Coerência Óptica , Ucrânia
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