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1.
J Chem Phys ; 158(9): 094701, 2023 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-36889938

RESUMO

Porous solid films that promote large apparent contact angles are interesting systems since their wetting properties are dependent on both the surface structure and water penetration into the film. In this study, a parahydrophobic coating is made by sequential dip coating of titanium dioxide nanoparticles and stearic acid on polished copper substrates. The apparent contact angles are determined using the tilted plate method, and it is found that the liquid-vapor interaction decreases and water droplets are more likely to move off the film when the number of coated layers increases. Interestingly, it is found that under some conditions, the front contact angle can be smaller than the back contact angle. Scanning electron microscopy observations demonstrate that the coating process led to the formation of hydrophilic TiO2 nanoparticle domains and hydrophobic stearic acid flakes that allows heterogeneous wetting. By monitoring the electrical current through the water droplet to the copper substrate, it is found that the water drops penetrate the coating layer to make direct contact with the copper surface with a time delay and magnitude that depends on the coating thickness. This additional penetration of water into the porous film enhances the adhesion of the droplet to the film and provides a clue to understand the contact angle hysteresis.

2.
Phys Chem Chem Phys ; 25(4): 2671-2705, 2023 Jan 27.
Artigo em Inglês | MEDLINE | ID: mdl-36637007

RESUMO

Nanocomposite materials consist of nanometer-sized quantum objects such as atoms, molecules, voids or nanoparticles embedded in a host material. These quantum objects can be exploited as a super-structure, which can be designed to create material properties targeted for specific applications. For electromagnetism, such targeted properties include field enhancements around the bandgap of a semiconductor used for solar cells, directional decay in topological insulators, high kinetic inductance in superconducting circuits, and many more. Despite very different application areas, all of these properties are united by the common aim of exploiting collective interaction effects between quantum objects. The literature on the topic spreads over very many different disciplines and scientific communities. In this review, we present a cross-disciplinary overview of different approaches for the creation, analysis and theoretical description of nanocomposites with applications related to electromagnetic properties.

3.
Microbiome ; 10(1): 131, 2022 08 23.
Artigo em Inglês | MEDLINE | ID: mdl-35996183

RESUMO

BACKGROUND: Top-soil microbiomes make a vital contribution to the Earth's ecology and harbor an extraordinarily high biodiversity. They are also key players in many ecosystem services, particularly in arid regions of the globe such as the African continent. While several recent studies have documented patterns in global soil microbial ecology, these are largely biased towards widely studied regions and rely on models to interpolate the microbial diversity of other regions where there is low data coverage. This is the case for sub-Saharan Africa, where the number of regional microbial studies is very low in comparison to other continents. RESULTS: The aim of this study was to conduct an extensive biogeographical survey of sub-Saharan Africa's top-soil microbiomes, with a specific focus on investigating the environmental drivers of microbial ecology across the region. In this study, we sampled 810 sample sites across 9 sub-Saharan African countries and used taxonomic barcoding to profile the microbial ecology of these regions. Our results showed that the sub-Saharan nations included in the study harbor qualitatively distinguishable soil microbiomes. In addition, using soil chemistry and climatic data extracted from the same sites, we demonstrated that the top-soil microbiome is shaped by a broad range of environmental factors, most notably pH, precipitation, and temperature. Through the use of structural equation modeling, we also developed a model to predict how soil microbial biodiversity in sub-Saharan Africa might be affected by future climate change scenarios. This model predicted that the soil microbial biodiversity of countries such as Kenya will be negatively affected by increased temperatures and decreased precipitation, while the fungal biodiversity of Benin will benefit from the increase in annual precipitation. CONCLUSION: This study represents the most extensive biogeographical survey of sub-Saharan top-soil microbiomes to date. Importantly, this study has allowed us to identify countries in sub-Saharan Africa that might be particularly vulnerable to losses in soil microbial ecology and productivity due to climate change. Considering the reliance of many economies in the region on rain-fed agriculture, this study provides crucial information to support conservation efforts in the countries that will be most heavily impacted by climate change. Video Abstract.


Assuntos
Microbiota , Solo , Biodiversidade , Clima Desértico , Ecossistema , Microbiota/genética , Solo/química , Microbiologia do Solo
4.
Facts Views Vis Obgyn ; 11(2): 177-187, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31824638

RESUMO

Ovarian cancer (OC), is a disease difficult to diagnose in an early stage implicating a poor prognosis. The 5-year overall survival in Belgium has not changed in the last 18 years and remains 44 %. There is no effective screening method (secondary prevention) to detect ovarian cancer at an early stage. Primary prevention of ovarian cancer came in the picture through the paradigm shift that the fallopian tube is often the origin of ovarian cancer and not the ovary itself. Opportunistic bilateral salpingectomy (OBS) during benign gynaecological and obstetric surgery might have the potential to reduce the risk of ovarian cancer by as much as 65 %. Bilateral risk-reducing salpingectomy during a benign procedure is feasible, safe, appears to have no impact on the ovarian function and seems to be cost effective. The key question is whether we should wait for a RCT or implement OBS directly in our daily practice. Guidelines regarding OBS within our societies are therefore urgently needed. Our recommendation is to inform all women without a child wish, undergoing a benign gynaecological or obstetrical surgical procedure about the pro's and the con's of OBS and advise a bilateral salpingectomy. Furthermore, there is an urgent need for a prospective registry of OBS. The present article is the consensus text of the Flemish Society of Obstetrics and Gynaecology (VVOG) regarding OBS.

5.
Rev Sci Instrum ; 89(5): 053702, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29864796

RESUMO

In neutral helium atom microscopy, a beam of atoms is scanned across a surface. Though still in its infancy, neutral helium microscopy has seen a rapid development over the last few years. The inertness and low energy of the helium atoms (less than 0.1 eV) combined with a very large depth of field and the fact that the helium atoms do not penetrate any solid material at low energies open the possibility for a non-destructive instrument that can measure topology on the nanoscale even on fragile and insulating surfaces. The resolution is determined by the beam spot size on the sample. Fast resolution change is an attractive property of a microscope because it allows different aspects of a sample to be investigated and makes it easier to identify specific features. However up till now it has not been possible to change the resolution of a helium microscope without breaking the vacuum and changing parts of the atom source. Here we present a modified source design, which allows fast, step wise resolution change. The basic design idea is to insert a moveable holder with a series of collimating apertures in front of the source, thus changing the effective source size of the beam and thereby the spot size on the surface and thus the microscope resolution. We demonstrate a design with 3 resolution steps. The number of resolution steps can easily be extended.

6.
J Environ Manage ; 212: 99-107, 2018 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-29428658

RESUMO

One of the major environmental issues in Finland is the presence of large tracts of acid sulfate soil (ASS) landscapes along the coast. Accurately identifying the distribution of ASS sediments, and in particular soil pH, is essential for developing targeted management strategies. One approach is the use of digital soil mapping (DSM) with various ancillary information. Although electromagnetic (EM) induction data has shown potential in mapping ASS, few studies have been conducted to map the spatial distribution of pH at different depths. In this study, a DUALEM-21S was used to collect apparent soil electrical conductivity (ECa) data across a 23-ha field near Vaasa, which lies along the western coast of Finland. A quasi-3D inversion algorithm was used to calculate the estimated true electrical conductivity (σ - mS m-1). A calibration relationship was developed between σ and incubation-pH measured at various depths from topsoil (0-0.2 m), subsurface (0.2-0.4 m) and subsoil (e.g. 0.4-0.6 and 1.8-2 m) using an artificial neural network (ANN) model. The performance of the ANN model was good given the large R2 values for calibration (0.72) and validation (0.65). It was concluded that the combination of ECa data and quasi-3D inversion algorithm (in EM4Soil) was able to map the spatial distribution of incubation-pH associated within an ASS landscape. The approach has the potential to be applied across the coastal areas of Finland and elsewhere to map incubation-pH and identify active-ASS areas and thereby improve the management of these areas.


Assuntos
Imageamento Tridimensional , Solo/química , Sulfatos/análise , Monitoramento Ambiental , Finlândia , Software
7.
Mol Ecol ; 26(16): 4197-4210, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28570031

RESUMO

Across several animal taxa, the evolution of sociality involves a suite of characteristics, a "social syndrome," that includes cooperative breeding, reproductive skew, primary female-biased sex ratio, and the transition from outcrossing to inbreeding mating system, factors that are expected to reduce effective population size (Ne). This social syndrome may be favoured by short-term benefits but come with long-term costs, because the reduction in Ne amplifies loss of genetic diversity by genetic drift, ultimately restricting the potential of populations to respond to environmental change. To investigate the consequences of this social life form on genetic diversity, we used a comparative RAD-sequencing approach to estimate genomewide diversity in spider species that differ in level of sociality, reproductive skew and mating system. We analysed multiple populations of three independent sister-species pairs of social inbreeding and subsocial outcrossing Stegodyphus spiders, and a subsocial outgroup. Heterozygosity and within-population diversity were sixfold to 10-fold lower in social compared to subsocial species, and demographic modelling revealed a tenfold reduction in Ne of social populations. Species-wide genetic diversity depends on population divergence and the viability of genetic lineages. Population genomic patterns were consistent with high lineage turnover, which homogenizes the genetic structure that builds up between inbreeding populations, ultimately depleting genetic diversity at the species level. Indeed, species-wide genetic diversity of social species was 5-8 times lower than that of subsocial species. The repeated evolution of species with this social syndrome is associated with severe loss of genomewide diversity, likely to limit their evolutionary potential.


Assuntos
Variação Genética , Genética Populacional , Comportamento Social , Aranhas/genética , Animais , Comportamento Animal , Endogamia , Aranhas/classificação
8.
J Microsc ; 265(3): 287-297, 2017 03.
Artigo em Inglês | MEDLINE | ID: mdl-27911467

RESUMO

Scanning electron microscopy is perhaps the most important method for investigating and characterizing nanostructures. A well-known challenge in scanning electron microscopy is the investigation of insulating materials. As insulating materials do not provide a path to ground they accumulate charge, evident as image drift and image distortions. In previous work, we have seen that sample charging in arrays of metal nanoparticles on glass substrates leads to a shrinkage effect, resulting in a measurement error in the nanoparticle dimension of up to 15% at 10 kV and a probe current of 80 ± 10 pA. In order to investigate this effect in detail, we have fabricated metal nanostructures on insulating borosilicate glass using electron beam lithography. Electron beam lithography allows us to tailor the design of our metal nanostructures and the area coverage. The measurements are carried out using two commonly available secondary electron detectors in scanning electron microscopes, namely, an InLens- and an Everhart-Thornley detector. We identify and discriminate several contributions to the effect by varying microscope settings, including the size of the aperture, the beam current, the working distance and the acceleration voltage. We image metal nanostructures of various sizes and geometries, investigating the influence of scan-direction of the electron beam and secondary electron detector used for imaging. The relative measurement error, which we measure as high as 20% for some settings, is found to depend on the acceleration voltage and the type of secondary electron detector used for imaging. In particular, the Everhart-Thornley detectors lower sensitivity to SE1 electrons increase the magnitude of the shrinkage of up to 10% relative to the InLens measurements. Finally, a method for estimating charge balance in insulating samples is presented.

9.
J Synchrotron Radiat ; 19(Pt 1): 30-8, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-22186641

RESUMO

The new third-generation synchrotron radiation source PETRA III located at the Deutsches Elektronen-Synchrotron DESY in Hamburg, Germany, has been operational since the second half of 2009. PETRA III is designed to deliver hard X-ray beams with very high brilliance. As one of the first beamlines of PETRA III the high-resolution diffraction beamline P08 is fully operational. P08 is specialized in X-ray scattering and diffraction experiments on solids and liquids where extreme high resolution in reciprocal space is required. The resolving power results in the high-quality PETRA III beam and unique optical elements such as a large-offset monochromator and beryllium lens changers. A high-precision six-circle diffractometer for solid samples and a specially designed liquid diffractometer are installed in the experimental hutch. Regular users have been accepted since summer 2010.

10.
Diabet Med ; 26(12): 1296-300, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-20002485

RESUMO

AIMS: Individuals with diabetic retinopathy (DR) represent a high-risk group who would benefit from intensive metabolic control and risk factor management. This brief report examines quality of care among diabetic patients attending a tertiary retinal clinic. METHODS: A cross-sectional survey, notes review, and slit-lamp examination was conducted in 139 diabetic patients attending a specialist retinal clinic to assess the quality of comprehensive diabetes care. DR was graded according to the Early Treatment Diabetic Retinopathy Study scale. RESULTS: The prevalence of non-proliferative DR (NPDR) and proliferative DR (PDR) was 39.6 and 35.2%, respectively. The prevalence of microalbuminuria in patients with no DR, NPDR and PDR was 32, 54.1 and 68.8%, respectively. Glycaemic control was suboptimal (mean HbA(1c) 8.0 +/- 1.8%) and 15.8% were current smokers. Drugs affecting the renin-angiotensin system were used by only 61.9% of patients with both DR and microalbuminuria, and aspirin by only 35.3%. CONCLUSIONS: These data suggest that diabetes care in this high-risk population with established microvascular complications was suboptimal. Specialist clinics dealing with diabetic complications may be a setting where quality improvement strategies to reduce morbidity and mortality should be focused.


Assuntos
Atenção à Saúde/normas , Diabetes Mellitus Tipo 1/terapia , Diabetes Mellitus Tipo 2/terapia , Retinopatia Diabética/epidemiologia , Adulto , Idoso , Albuminúria/epidemiologia , Estudos Transversais , Diabetes Mellitus Tipo 1/sangue , Diabetes Mellitus Tipo 1/complicações , Diabetes Mellitus Tipo 2/sangue , Diabetes Mellitus Tipo 2/complicações , Retinopatia Diabética/diagnóstico , Feminino , Hemoglobinas Glicadas/análise , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação de Processos e Resultados em Cuidados de Saúde , Prevalência
11.
Eur J Vasc Endovasc Surg ; 32(4): 431-8, 2006 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16807001

RESUMO

OBJECTIVES: To investigate whether patency of a thin walled 8 mm fluoropassivated Dacron graft was similar to that of a standard 8mm PTFE graft for femorofemoral crossover bypass surgery. DESIGN: A randomised multicentre clinical trial comparing two vascular grafts with participation of 10 departments of vascular surgery in Denmark, Sweden and Norway. PATIENTS AND METHODS: 198 patients were randomised to PTFE (n=107) or fluoropolymer-coated Dacron grafts (n=91), 63% underwent surgery for claudication, 27% for ischaemic rest pain and 10% for tissue loss. The median follow-up time was 24 months (IQR 19-26 months). RESULTS: The primary patency rate of the two grafts was similar (log rank test: p=0.35). The primary patency rates (95% CI) for coated Dacron and PTFE grafts were 92% (86-98) and 94% (89-99) at 12 months and 87% (74-95) and 93% (87-99) at 24 months, respectively. CONCLUSION: In patients with unilateral iliac artery disease not amenable to angioplasty, the femoral-femoral bypass is durable and effective. No difference in patency was found between the two graft materials (fluoropolymer coated Dacron and PTFE).


Assuntos
Implante de Prótese Vascular , Prótese Vascular , Materiais Revestidos Biocompatíveis , Artéria Femoral/cirurgia , Polímeros de Fluorcarboneto , Polietilenotereftalatos , Politetrafluoretileno , Idoso , Prótese Vascular/efeitos adversos , Implante de Prótese Vascular/efeitos adversos , Feminino , Oclusão de Enxerto Vascular/etiologia , Humanos , Claudicação Intermitente/cirurgia , Isquemia/cirurgia , Perna (Membro)/irrigação sanguínea , Masculino , Complicações Pós-Operatórias , Fatores de Risco , Grau de Desobstrução Vascular
12.
Am J Ophthalmol ; 132(5): 792-4, 2001 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11704049

RESUMO

PURPOSE: The purpose of this study was to investigate the role of leptin in choroidal neovascularization. METHODS: We examined the localization of leptin by immunohistochemistry in nine choroidal neovascular membranes surgically excised from patients with age-related macular degeneration, idiopathic choroidal neovascularization, and ocular histoplasmosis. Controls included omission of primary antibody, use of an irrelevant primary antibody and leptin staining of posterior segment of four normal donor eyes. RESULTS: Leptin was present in eight membranes and appeared vesicular, within the cytoplasm. The more vascular membranes and those consisting of a larger number of retinal pigment epithelium cells were associated with greater leptin staining. Leptin was not seen in the posterior segment of the four normal eyes. CONCLUSION: We suggest that leptin plays an active role in choroidal neovascularization, although further experiments are necessary to establish a causal relationship.


Assuntos
Neovascularização de Coroide/metabolismo , Leptina/metabolismo , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Técnicas Imunoenzimáticas , Degeneração Macular/metabolismo , Masculino , Pessoa de Meia-Idade , Molécula-1 de Adesão Celular Endotelial a Plaquetas/metabolismo
13.
Can J Ophthalmol ; 36(4): 187-96, 2001 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-11428527

RESUMO

BACKGROUND: Diabetic retinopathy is a leading cause of vision loss in North America. We compared mydriatic seven-field stereoscopic digital imaging to 100 ASA slide film photography for the identification of diabetic retinopathy via teleophthalmology. METHODS: Patients from a northern Alberta community with diabetes mellitus diagnosed by a physician were asked to participate in a teleophthalmology pilot project. Patients were enrolled at four different times between October 1999 and June 2000. Seven 30 degree fields of the retina were photographed with both slide film and digital imaging (resolution 2008 x 3040 pixels) through a dilated pupil. Slide film was developed and reviewed in a masked fashion by a retinal specialist. Digital images for each patient were transmitted by satellite to Edmonton and analysed a minimum of 2 months after the original slide film. Retinal abnormalities were graded with the use of the Early Treatment Diabetic Retinopathy Study extension of the modified Airlie House classification. We calculated the sensitivity and specificity of digital imaging for the identification of features of diabetic retinopathy as seen on slide film. Pearson's correlation coefficient was also calculated. RESULTS: A total of 121 patients (241 eyes), of whom 114 (94.2%) had non-insulin-dependent diabetes, participated in the study. The average duration of diabetes was 8.5 years. Of the 121 patients 57 (47.1%) had diabetic retinopathy, 12 (9.9%) had clinically significant macular edema and 2 (1.6%) had neovascularization. Pearson's correlation coefficient for the presence of retinopathy between slide film and stereoscopic digital imaging was 0.92 for microaneurysms, 0.80 for hemorrhages, 0.45 for intraretinal microvascular abnormalities, 0.32 for venous beading, 1.00 for neovascularization of the disc, 1.00 for neovascularization elsewhere in the retina and 0.97 for clinically significant macular edema (p < 0.001). The correlation between the two techniques for severe nonproliferative diabetic retinopathy (NPDR) was 0.86 and for high-risk proliferative diabetic retinopathy 1.00 (p < 0.001). INTERPRETATION: Stereoscopic digital imaging has a high level of correlation with slide film for the identification of most features of diabetic retinopathy, including microaneurysms, hemorrhage, severe NPDR, high-risk proliferative diabetic retinopathy and clinically significant macular edema.


Assuntos
Retinopatia Diabética/diagnóstico , Processamento de Imagem Assistida por Computador/métodos , Fotografação/métodos , Consulta Remota/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Diabetes Mellitus Tipo 2/complicações , Diagnóstico por Imagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
14.
Diabetes Technol Ther ; 2(4): 583-7, 2000.
Artigo em Inglês | MEDLINE | ID: mdl-11469622

RESUMO

Diabetic eye disease is present in remote communities across Canada. A pilot study was designed to assess the feasibility of stereoscopic digital imaging to identify levels of diabetic retinopathy via teleophthalmology. Diabetic patients were assessed for diabetic retinopathy by seven field stereoscopic digital imaging through a dilated pupil. Images were transferred by satellite to a tertiary eye center for review by a retinal specialist. Images were viewed stereoscopically on a video monitor, with grading of all images using a modified Early Treatment Diabetic Retinopathy Study (ETDRS) classification. Patients found to have treatable diabetic retinopathy were transferred to a tertiary eye center for assessment and treatment by a retinal specialist. One hundred patients (199 eyes) had stereoscopic digital imaging of the retina. Microaneurysms were identified in 70 eyes, hard exudates in 31 eyes. Two eyes were identified with neovascularization of the disc (NVD) and 15 eyes with clinically significant macular edema (CSME). All eyes identified by stereoscopic digital imaging with treatable disease were confirmed by clinical examination with contact lens biomicroscopy. Stereoscopic digital imaging of the retina enables the identification of diabetic retinopathy. Further research is needed to delineate the sensitivity and specificity of stereoscopic digital imaging when compared to slide film and clinical examination.


Assuntos
Retinopatia Diabética/diagnóstico , Angiofluoresceinografia , Oftalmologia/métodos , Telemedicina , Alberta , Canadá , Feminino , Humanos , Masculino , Fotografação , Projetos Piloto , Consulta Remota/instrumentação , Consulta Remota/organização & administração , Software , Telemedicina/instrumentação , Telemedicina/organização & administração
15.
Ophthalmic Surg Lasers ; 30(8): 619-30, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-10507564

RESUMO

BACKGROUND AND OBJECTIVE: To evaluate a macular buckle for exudative choroidal neovascularization secondary to age-related macular degeneration (ARMD). PATIENTS AND METHODS: Forty-two eyes with choroidal neovascular membranes (CNVM) secondary to ARMD underwent surgical placement of a macular buckle. A Gore-Tex strip (2.0-2.5 mm wide) was button-holed through a 5 mm diameter silicone sponge (9 mm long) and placed behind the macula underneath the CNVM by the same surgeon (Dr Peyman) in all cases. Follow-up ranged from 7-76 months (mean, 20.9 months). RESULTS: Of 12 eyes with classic subfoveal CNVM: 4 (33%) gained 2 or more lines of Snellen visual acuity; 3 (25%) gained 1 line, remained the same, or lost 1 line; and 5 (42%) lost 2 or more lines (range + 6 to - 6 lines). Of 22 eyes with ill-defined subfoveal CNVM: 12 (54%) gained 1 line, remained the same, or lost 1 line; and 10 (46%) lost 2 or more lines (range + 1 to - 8 lines). Eight eyes with ill-defined juxtafoveal CNVM had the following visual acuity outcomes: 5 eyes (62%) maintained the same level of Snellen visual acuity (gained 1, 0, or lost 1 line); and 3 (38%) got worse (lost 2 or more lines of Snellen visual acuity, range + 1 to - 6 lines). Ten eyes (24%) bled subretinally during the follow-up period (average 11.5 months, range 14 days to 27 months), all outside the area of indentation of the macular buckle. CONCLUSIONS: The macular buckle treatment for exudative subretinal choroidal neovascular membranes in ARMD stabilized visual decline and displaced significant subfoveal hemorrhage.


Assuntos
Neovascularização de Coroide/cirurgia , Macula Lutea/cirurgia , Degeneração Macular/cirurgia , Politetrafluoretileno , Próteses e Implantes , Idoso , Idoso de 80 Anos ou mais , Neovascularização de Coroide/etiologia , Exsudatos e Transudatos , Feminino , Seguimentos , Fundo de Olho , Humanos , Degeneração Macular/complicações , Masculino , Pessoa de Meia-Idade , Implantação de Prótese , Técnicas de Sutura , Acuidade Visual
16.
Int Ophthalmol ; 21(2): 87-91, 1997.
Artigo em Inglês | MEDLINE | ID: mdl-9405990

RESUMO

BACKGROUND: The surgical management of macular holes has been a subject of controversy in recent years. Various techniques such as vitrectomy, membrane peeling, and gas tamponade with or without transforming growth factor-beta 2, and recently the use of autologous platelets have produced closure rates from 58% to 96%, depending on the stage of the hole. METHODS: The authors present preliminary results in a study of 19 consecutive patients with stage 3 or stage 4 macular hole who underwent vitrectomy followed by placement of an absorbable partially cross-linked gelatin plug in the macular hole. The vitreous cavity was filled with a nonexpanding gas or air alone; the patient was instructed to maintain prone positioning for 2-3 days. RESULTS: Anatomic attachment of the edges of the macular hole was achieved in 19 out of 19 patients with a minimum follow-up period of 6 months (average 11.5 months). CONCLUSIONS: A cross-linked gelatin plug can effectively reattach the edges of macular holes of stages 3 and 4. Its use is recommended only in macular holes in high myopes with posterior staphyloma or recurrent macular hole.


Assuntos
Próteses e Implantes , Perfurações Retinianas/cirurgia , Absorção , Adulto , Idoso , Desenho de Equipamento , Feminino , Gelatina/farmacocinética , Humanos , Masculino , Ilustração Médica , Pessoa de Meia-Idade , Estudos Prospectivos , Perfurações Retinianas/fisiopatologia , Resultado do Tratamento , Acuidade Visual/fisiologia , Vitrectomia
17.
Ophthalmic Surg Lasers ; 27(2): 154-5, 1996 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-8640442

RESUMO

A technique of performing a relaxing retinotomy under the perfluorocarbon liquid perfluoroperhydropenanthrene (Vitreon, Vitrophage, Inc., Lyons, IL) is described. This procedure allows perfluorocarbon liquid to be used to maintain the retina in the desired position and to dissect proliferative membranes prior to the retinotomy without having to remove the Vitreon to perform the retinotomy.


Assuntos
Fluorocarbonos/administração & dosagem , Retina/cirurgia , Descolamento Retiniano/cirurgia , Vitreorretinopatia Proliferativa/cirurgia , Humanos , Oftalmologia/métodos
18.
Ophthalmic Surg ; 26(4): 330-3, 1995.
Artigo em Inglês | MEDLINE | ID: mdl-8532285

RESUMO

We describe two cases in which a new retinotomy technique is used to remove subretinal neovascular membranes. The direction and location of the retinotomy are of ultimate importance in prevention of damage to retinal nerve fibers and the corresponding visual field loss. The retinotomy is made with an angled 20-gauge needle in nondiathermized retina. The direction of the retinotomy is parallel to the nerve fiber layer and located over the subretinal neovascular membrane. No laser retinopexy was necessary after removal of the subretinal neovascular membrane.


Assuntos
Retina/cirurgia , Neovascularização Retiniana/cirurgia , Membrana Celular , Angiofluoresceinografia , Fundo de Olho , Humanos , Masculino , Pessoa de Meia-Idade , Neovascularização Retiniana/etiologia , Acuidade Visual
19.
Ophthalmic Surg ; 26(1): 29-33, 1995.
Artigo em Inglês | MEDLINE | ID: mdl-7746621

RESUMO

We report posterior segment complications encountered with the use of the liquid perfluorocarbon, perfluoroperhydrophenanthrene (Vitreon) as an intraoperative adjunct to vitreoretinal surgery in 640 patients participating in the Vitreon Collaborative Study. We also evaluated postoperative complications in 60 patients in whom Viteron was intentionally left inside the vitreous cavity for periods ranging from 5 days to 4 weeks as a short-term retinal tamponade. The five most common postoperative complications among these patients as a whole were recurrent retinal detachment, with or without proliferative vitreoretinopathy (11.28%); macular pucker (5.85%); fibrinous reaction (4%); residual Vitreon (3.85%); and vitreous hemorrhage (2.57%).


Assuntos
Fluorocarbonos/efeitos adversos , Doenças Retinianas/etiologia , Vitrectomia/efeitos adversos , Corpo Vítreo/patologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Oftalmopatias/etiologia , Oftalmopatias/cirurgia , Feminino , Humanos , Incidência , Lactente , Complicações Intraoperatórias/etiologia , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/etiologia , Doenças Retinianas/cirurgia , Corpo Vítreo/cirurgia
20.
Ophthalmic Surg ; 25(10): 723-5, 1994.
Artigo em Inglês | MEDLINE | ID: mdl-7898868

RESUMO

We report a case of subretinal hemorrhage associated with age-related macular degeneration, in which tissue plasminogen activating factor was used to help remove the subretinal blood. The surgical technique involved using multiple small retinotomy sites and alternating suction and backflushing to produce fluid flow from the subretinal space to the vitreous cavity.


Assuntos
Degeneração Macular/complicações , Retina/cirurgia , Hemorragia Retiniana/cirurgia , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Retina/efeitos dos fármacos , Hemorragia Retiniana/tratamento farmacológico , Hemorragia Retiniana/etiologia , Ativador de Plasminogênio Tecidual/uso terapêutico , Vitrectomia
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