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1.
Retina ; 44(7): 1171-1179, 2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-38437847

RESUMO

PURPOSE: To examine postoperative outcomes of internal limiting membrane peeling (ILMP) versus flap (ILMF) in the closure of full-thickness macular holes. METHODS: Retrospective chart review of patients who underwent pars plana vitrectomy and gas tamponade with ILMP or ILMF to close full-thickness macular hole at the Atrium Health Wake Forest Baptist from January 2012 to October 2022 with at least 3 months follow-up. Main outcome measures were type 1 primary full-thickness macular hole closure and postoperative best-corrected visual acuity in mean logMAR. RESULTS: One hundred thirty and 30 eyes underwent ILMP and ILMF, respectively. There were no significant differences in baseline characteristics between the groups. Ninety-six percent of ILMP eyes and 90% of ILMF eyes achieved primary hole closure ( P = 0.29). Among all eyes with primary hole closure, best-corrected visual acuity at 1 year was not different between the groups, but when stratified by lens status, it was superior in the ILMP versus ILMF group in pseudophakic eyes: the estimated least-squares mean best-corrected visual acuity (Snellen equivalent) (95% confidence interval) was 0.42 (20/50) (0.34, 0.49) in the ILMP group and 0.71 (20/100) (0.50, 0.92) in the ILMF group. CONCLUSION: Internal limiting membrane peeling and ILMF techniques yielded similarly high full-thickness macular hole closure rates. In pseudophakic eyes with primary hole closure, ILMF eyes had worse best-corrected visual acuity at 1 year.


Assuntos
Membrana Basal , Tamponamento Interno , Perfurações Retinianas , Retalhos Cirúrgicos , Tomografia de Coerência Óptica , Acuidade Visual , Vitrectomia , Humanos , Perfurações Retinianas/cirurgia , Perfurações Retinianas/fisiopatologia , Estudos Retrospectivos , Acuidade Visual/fisiologia , Vitrectomia/métodos , Masculino , Feminino , Idoso , Membrana Basal/cirurgia , Tamponamento Interno/métodos , Pessoa de Meia-Idade , Seguimentos , Resultado do Tratamento , Membrana Epirretiniana/cirurgia , Membrana Epirretiniana/fisiopatologia
2.
Retin Cases Brief Rep ; 18(1): 15-17, 2024 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-35963000

RESUMO

PURPOSE: The purpose of this study was to describe two cases of traumatic lens subluxation resulting from pickleball injury. METHODS: This is a case series. RESULTS: A 77-year-old man presented with worsening vision and was noted to have subluxation of his intraocular lens 10 days after being struck in the eye with a pickleball. The patient underwent a lens exchange with scleral fixation. A 76-year-old woman presented with blurry vision on the same day as her injury and was noted to have subluxation of her crystalline lens. She also underwent a lens insertion with scleral fixation. However, she experienced additional complications of postoperative cystoid macular edema and traumatic glaucoma. CONCLUSION: We recommend increased use of eye protection in pickleball.


Assuntos
Traumatismos Oculares , Subluxação do Cristalino , Cristalino , Lentes Intraoculares , Masculino , Feminino , Humanos , Idoso , Implante de Lente Intraocular/efeitos adversos , Subluxação do Cristalino/diagnóstico , Subluxação do Cristalino/etiologia , Subluxação do Cristalino/cirurgia , Lentes Intraoculares/efeitos adversos , Traumatismos Oculares/complicações , Traumatismos Oculares/diagnóstico , Estudos Retrospectivos , Complicações Pós-Operatórias/cirurgia
3.
Retina ; 43(11): 1996-2002, 2023 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-37490751

RESUMO

PURPOSE: To compare features of endogenous endophthalmitis associated with injection drug use (IDU) to endogenous endophthalmitis from other etiologies. METHODS: The authors retrospectively collected data on patients with endogenous endophthalmitis due to IDU or other causes from three academic tertiary care centers over a six-year period. Differences in presenting characteristics, culture results, treatment, and visual acuity were compared between groups. RESULTS: Thirty-eight patients (34%) had IDU-associated endogenous endophthalmitis while 75 patients (67%) had endogenous endophthalmitis from other causes. Compared with patients in the non-IDU group, IDU patients were significantly younger, more frequently male, had longer duration of symptoms at diagnosis, and were less likely to have bilateral disease ( P < 0.05 for all). Injection drug use patients were less likely to have a systemic infection source identified (29% vs. 71%, P < 0.001) or have positive cultures (47% vs. 80%, P < 0.001). The IDU group was less likely to be admitted to the hospital (71% vs. 92%, P = 0.005) and less likely to receive treatment with intravenous antimicrobials (55% vs. 83%, P = 0.003). Visual acuity did not significantly differ between groups. CONCLUSION: Endophthalmitis related to IDU presents in younger patients with less comorbidities and frequently without positive cultures or an identifiable systemic source; therefore, a high index of suspicion is needed to identify this disease.


Assuntos
Endoftalmite , Infecções Oculares Bacterianas , Humanos , Masculino , Estudos Retrospectivos , Vitrectomia , Endoftalmite/diagnóstico , Endoftalmite/tratamento farmacológico , Endoftalmite/epidemiologia , Acuidade Visual , Antibacterianos/uso terapêutico , Infecções Oculares Bacterianas/diagnóstico , Infecções Oculares Bacterianas/tratamento farmacológico , Infecções Oculares Bacterianas/epidemiologia
4.
Ophthalmic Surg Lasers Imaging Retina ; 54(7): 411-416, 2023 07.
Artigo em Inglês | MEDLINE | ID: mdl-37418672

RESUMO

BACKGROUND AND OBJECTIVE: To investigate the impact of social determinants of health on the presentation, treatment, and outcomes of branch retinal vein occlusion (BRVO) with cystoid macular edema (CME). PATIENTS AND METHODS: A retrospective chart review was conducted of patients with BRVO and CME treated with anti-vascular endothelial growth factor (anti-VEGF) injections at Atrium Health Wake Forest Baptist from 2013 to 2021. Patients' baseline characteristics including visual acuity (VA), age, sex, race, Area Deprivation Index (ADI), insurance status, baseline central macular thickness (CMT), treatment details, final VA, and final CMT were recorded. The primary outcome measure was final VA comparing more and less deprived groups, and White and non-White groups. RESULTS: Two hundred forty-four eyes of 240 patients were included. Patients with higher socioeconomic deprivation scores had thicker final CMT (P = 0.05). Non-White patients had worse presenting (P = 0.01) and final VA (P = 0.02). CONCLUSION: This study demonstrated disparities in presentation and outcomes based on socioeconomic status and race in patients with BRVO and CME treated with anti-VEGF therapy. [Ophthalmic Surg Lasers Imaging Retina 2023;54:411-416.].


Assuntos
Edema Macular , Oclusão da Veia Retiniana , Humanos , Oclusão da Veia Retiniana/diagnóstico , Oclusão da Veia Retiniana/tratamento farmacológico , Edema Macular/diagnóstico , Edema Macular/tratamento farmacológico , Edema Macular/etiologia , Estudos Retrospectivos , Determinantes Sociais da Saúde , Injeções , Injeções Intravítreas , Inibidores da Angiogênese , Tomografia de Coerência Óptica/métodos
5.
Ophthalmic Surg Lasers Imaging Retina ; 54(5): 297-300, 2023 05.
Artigo em Inglês | MEDLINE | ID: mdl-37022313

RESUMO

In this case report, we describe a 34-year-old male patient who presented with vision loss and was found to have profound occlusive retinal vasculopathy. His initial laboratory studies were unremarkable, but five weeks after his ocular symptoms began, he developed acute multi-organ failure and was ultimately diagnosed with atypical hemolytic uremic syndrome (aHUS). His course was complicated by a stroke, respiratory distress requiring intubation, long-term hemodialysis, and eventually death. Occlusive retinal vasculopathy may be the presenting finding in aHUS, although thrombotic microangiopathy syndromes typically present with acute kidney injury and or failure, hemolytic anemia, and thrombocytopenia. [Ophthalmic Surg Lasers Imaging Retina 2023;54:297-300.].


Assuntos
Síndrome Hemolítico-Urêmica Atípica , Microangiopatias Trombóticas , Vitreorretinopatia Proliferativa , Masculino , Humanos , Adulto , Síndrome Hemolítico-Urêmica Atípica/complicações , Síndrome Hemolítico-Urêmica Atípica/diagnóstico , Microangiopatias Trombóticas/complicações , Microangiopatias Trombóticas/diagnóstico , Diálise Renal/efeitos adversos , Diagnóstico Diferencial , Vitreorretinopatia Proliferativa/diagnóstico
6.
Retin Cases Brief Rep ; 17(5): 644-647, 2023 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-35199649

RESUMO

PURPOSE: To describe a case of paracentral acute middle maculopathy and ocular ischemic syndrome after intranasal steroid injection. METHODS: Case report. RESULTS: Following an intranasal steroid injection, the patient experienced an episode of amaurosis fugax in her right eye lasting several minutes. Afterward, her visual acuity returned to baseline, but she noted a persistent central scotoma. Optical coherence tomography demonstrated paracentral acute middle maculopathy and fluorescein angiography showed staining and leakage to peripheral vessels concerning for diffuse ischemia. CONCLUSION: Steroid injections to the face and nasopharynx may result in ischemic and vaso-occlusive events in the retina. Ophthalmologists and other physicians performing these procedures need to be aware of this potential adverse outcome.


Assuntos
Degeneração Macular , Doenças Retinianas , Doenças Vasculares , Feminino , Humanos , Doenças Retinianas/induzido quimicamente , Doenças Retinianas/diagnóstico , Doença Aguda , Isquemia/induzido quimicamente , Isquemia/diagnóstico , Retina , Degeneração Macular/complicações , Esteroides/efeitos adversos
8.
Retin Cases Brief Rep ; 16(6): 685-687, 2022 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-33055554

RESUMO

PURPOSE: We describe a case of endophthalmitis caused by Streptococcus salivarius presenting as a retinal vasculitis less than 24 hours after intravitreal injection. METHODS: A case report. RESULTS: The patient progressed from a hemorrhagic retinal vasculitis to severe endophthalmitis with no view to the posterior segment within 24 hours. The visual acuity progressed from 20 of 20 preinjection to light perception within less than 48 after injection. Vitreous tap and injection was performed within 24 hours of intravitreal aflibercept injection, followed by pars plana vitrectomy the next day. The final visual acuity was hand motions. CONCLUSION: Streptococcus salivarius is a virulent organism that may cause an endophthalmitis early after intravitreal injection with an unusual presentation of hemorrhagic retinal vasculitis. A high index of suspicion for infectious endophthalmitis should be maintained for all patients presenting with ocular inflammation and worsening vision in the days after intravitreal injections.


Assuntos
Endoftalmite , Infecções Oculares Bacterianas , Vasculite Retiniana , Humanos , Vasculite Retiniana/tratamento farmacológico , Endoftalmite/diagnóstico , Endoftalmite/etiologia , Endoftalmite/tratamento farmacológico , Receptores de Fatores de Crescimento do Endotélio Vascular , Injeções Intravítreas , Vitrectomia/efeitos adversos , Estudos Retrospectivos , Antibacterianos/uso terapêutico , Infecções Oculares Bacterianas/tratamento farmacológico
9.
Retin Cases Brief Rep ; 16(1): 67-69, 2022 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-31339874

RESUMO

BACKGROUND/PURPOSE: To describe management of anterior migration of a fluocinolone acetonide(FAc) intravitreal implant. METHODS: A retrospective case report. A 61-year-old man with diabetic macular edema and prior vitrectomy had anterior migration of a FAc implant. Anterior segment photos and optical coherence tomography were performed. RESULTS: Approximately 3 months after FAc implant was administered, it was noted to have migrated into the anterior chamber. Vision, intraocular pressure, and optical coherence tomography imaging initially remained stable, and no evidence of detectable corneal edema developed in 30 months of follow-up. However, at 36 months of follow-up, after second FAc implant injection, mild corneal edema developed,suspected to be related to the migrating implants. CONCLUSION: Anterior migration of a FAc implant may lead to less rapid and severe corneal decompensation compared with other steroid implants. Despite this, delayed corneal edema may occur. Careful monitoring of the cornea and intraocular pressure is recommended in cases of anterior FAc migration.


Assuntos
Fluocinolona Acetonida , Migração de Corpo Estranho , Retinopatia Diabética/tratamento farmacológico , Implantes de Medicamento , Migração de Corpo Estranho/terapia , Humanos , Edema Macular/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
10.
Ophthalmol Retina ; 5(12): 1263-1268, 2021 12.
Artigo em Inglês | MEDLINE | ID: mdl-33667700

RESUMO

PURPOSE: To determine the prevalence of and to characterize vitreous and chorioretinal lesions, to identify causative organisms, and to correlate symptoms with ophthalmic involvement in people who inject drugs and are hospitalized with bloodstream infection (BSI), related metastatic foci of infection (MFI), or both. DESIGN: An academic hospital-based cross-sectional study. PARTICIPANTS: Patients admitted with BSI or MFI related to injection drug use (IDU). METHODS: Patients underwent a complete eye examination within 72 hours of enrollment. Characteristics including gender; age; race; injection drug of choice (DOC); presence of coinfection with hepatitis B, hepatitis C, or human immunodeficiency virus; pathogen causing systemic infection and type of infection; and history of prior infection related to IDU were recorded. MAIN OUTCOME MEASURES: Presence of vitreous or chorioretinal findings, or both. RESULTS: Ninety-one unique patients with 96 separate hospitalizations for systemic infection were enrolled from March 28, 2018, through March 30, 2020. Vitreous or chorioretinal involvement was identified in 16 of 96 patients (16.7%). The most common ocular findings were intraretinal or white-centered hemorrhage in 9 of 96 patients, chorioretinal infiltrate in 8 of 96 patients, endophthalmitis in 5 of 96 patients, and cotton wool spots in 3 of 96 patients. Of the patients with ocular involvement, only 7 of 16 patients (44%) were symptomatic, and 5 of these were patients with endophthalmitis; the others showed chorioretinal infiltrates or intraretinal or white-centered hemorrhage and cotton wool spots. Staphylococcus aureus was the most common causative pathogen in patients with and without ocular findings. Presence of ocular symptoms, worse visual acuity, and injection DOC of methamphetamine were correlated with the presence of ocular findings. CONCLUSIONS: Patients without ocular symptoms with systemic infections related to IDU may have chorioretinal findings. Further study is needed to characterize better the epidemiologic features of these infections and to identify risk factors for ocular involvement in people who inject drugs.


Assuntos
Corioide/diagnóstico por imagem , Usuários de Drogas , Endoftalmite/diagnóstico , Infecções Oculares Bacterianas/diagnóstico , Retina/diagnóstico por imagem , Infecções Estafilocócicas/diagnóstico , Corpo Vítreo/diagnóstico por imagem , Adolescente , Adulto , Idoso , Estudos Transversais , Endoftalmite/microbiologia , Infecções Oculares Bacterianas/microbiologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Infecções Estafilocócicas/microbiologia , Staphylococcus aureus/isolamento & purificação , Acuidade Visual , Adulto Jovem
11.
Transl Vis Sci Technol ; 9(2): 60, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-33294301

RESUMO

Purpose: To evaluate the performance of a deep learning algorithm in the detection of referral-warranted diabetic retinopathy (RDR) on low-resolution fundus images acquired with a smartphone and indirect ophthalmoscope lens adapter. Methods: An automated deep learning algorithm trained on 92,364 traditional fundus camera images was tested on a dataset of smartphone fundus images from 103 eyes acquired from two previously published studies. Images were extracted from live video screenshots from fundus examinations using a commercially available lens adapter and exported as a screenshot from live video clips filmed at 1080p resolution. Each image was graded twice by a board-certified ophthalmologist and compared to the output of the algorithm, which classified each image as having RDR (moderate nonproliferative DR or worse) or no RDR. Results: In spite of the presence of multiple artifacts (lens glare, lens particulates/smudging, user hands over the objective lens) and low-resolution images achieved by users of various levels of medical training, the algorithm achieved a 0.89 (95% confidence interval [CI] 0.83-0.95) area under the curve with an 89% sensitivity (95% CI 81%-100%) and 83% specificity (95% CI 77%-89%) for detecting RDR on mobile phone acquired fundus photos. Conclusions: The fully data-driven artificial intelligence-based grading algorithm herein can be used to screen fundus photos taken from mobile devices and identify with high reliability which cases should be referred to an ophthalmologist for further evaluation and treatment. Translational Relevance: The implementation of this algorithm on a global basis could drastically reduce the rate of vision loss attributed to DR.


Assuntos
Aprendizado Profundo , Diabetes Mellitus , Retinopatia Diabética , Inteligência Artificial , Retinopatia Diabética/diagnóstico , Humanos , Encaminhamento e Consulta , Reprodutibilidade dos Testes
13.
Clin Ophthalmol ; 14: 1161-1163, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32431486

RESUMO

Telemedicine has emerged as a potential solution to face the disproportion between infants that need to be screened for retinopathy of prematurity (ROP) and the lack of ophthalmologists. We evaluated its utility in the follow-up after off-label intravitreal injection of bevacizumab. None of the treated infants ended up with bad anatomic outcome. Telemedicine is an alternative safe method to monitor patients after treatment.

14.
Ophthalmic Surg Lasers Imaging Retina ; 51(4): 220-224, 2020 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-32348538

RESUMO

BACKGROUND AND OBJECTIVE: To assess neurodevelopmental outcomes of infants with treatment-warranted retinopathy of prematurity (TW-ROP) treated with intravitreal bevacizumab (IVB) plus diode laser photocoagulation (DLP) compared to DLP alone. PATIENTS AND METHODS: A retrospective review was performed of infants who underwent treatment for TW-ROP with IVB+DLP or DLP alone from 2010 to 2017. Baseline characteristics and coexisting medical comorbidities were recorded. The presence of neurodevelopmental delay (NDD) at 2-year follow-up and composite Bayley-III scores were recorded. RESULTS: Sixty-six infants were included in the study; 18 received IVB+DLP, and 48 received DLP alone. Average Bayley-III scores for cognition, language, and motor, as well as rates of documental NDD, did not differ between the groups. CONCLUSION: This study does not demonstrate an increased risk of NDD in infants with TW-ROP treated with IVB+DLP compared with DLP alone. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:220-224.].


Assuntos
Bevacizumab/administração & dosagem , Desenvolvimento Infantil , Fotocoagulação a Laser/métodos , Macula Lutea/diagnóstico por imagem , Retinopatia da Prematuridade/terapia , Inibidores da Angiogênese/administração & dosagem , Feminino , Humanos , Recém-Nascido , Injeções Intravítreas , Masculino , Retinopatia da Prematuridade/diagnóstico , Estudos Retrospectivos , Fator A de Crescimento do Endotélio Vascular/antagonistas & inibidores
15.
Am J Ophthalmol Case Rep ; 15: 100515, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31341998

RESUMO

PURPOSE: To describe an unusual case of Bartonella henselae neuroretinitis complicated by macular hole (MH) development. OBSERVATIONS: A full-thickness macular hole developed in a 12-year-old boy in association with serology-confirmed Bartonella henselae neuroretinitis. Following a period of observation, the MH closed without intervention. CONCLUSION AND IMPORTANCE: MH may occur as a complication of neuroretinitis secondary to Cat-Scratch Disease.

16.
Ophthalmic Surg Lasers Imaging Retina ; 50(4): e125-e127, 2019 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-30998256

RESUMO

A 67-year-old female presented with vitreous hemorrhage and sub-internal limited membrane (ILM) hemorrhage in her right eye associated with ruptured retinal arterial macroaneurysm. During pars plana vitrectomy, intraoperative optical coherence tomography aided in the diagnosis of a small macular hole previously obscured by the sub-ILM hemorrhage. Nonexpansile gas was placed followed by postoperative prone positioning, and the hole closed successfully. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e125-e127.].


Assuntos
Aneurisma Roto/complicações , Macula Lutea/diagnóstico por imagem , Macroaneurisma Arterial Retiniano/complicações , Perfurações Retinianas/diagnóstico , Tomografia de Coerência Óptica/métodos , Vitrectomia/métodos , Idoso , Aneurisma Roto/diagnóstico , Aneurisma Roto/cirurgia , Feminino , Humanos , Período Intraoperatório , Macroaneurisma Arterial Retiniano/diagnóstico , Macroaneurisma Arterial Retiniano/cirurgia , Perfurações Retinianas/etiologia , Perfurações Retinianas/cirurgia
18.
Br J Ophthalmol ; 103(10): 1503-1506, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-30504489

RESUMO

PURPOSE: To determine if final visual acuity (VA) is affected by duration of macular detachment (DMD) within the first week of macula-off retinal detachment (RD). METHODS: This is a retrospective study of eyes that underwent repair within 7 days with vitrectomy or vitrectomy with scleral buckle for macula-off RD at Stanford University Hospital between 1 May 2007 and 1 May 2017. A generalised linear model was constructed using DMD, postoperative lens status, preoperative VA, patient age and surgeon as the independent variables and the final VA as the dependent variable. The main outcome measure was the final VA. RESULTS: Seventy-nine eyes met the entry criteria. Group 1 included 52 eyes with RD repaired within 3 days of DMD, and group 2 included 27 eyes repaired between 4 and 7 days of DMD. The average final VA in group 1 eyes was logarithm of the minimum angle of resolution (logMAR) 0.21 (Snellen 20/33) and in group 2 eyes was logMAR 0.54 (Snellen 20/69). In group 1 and group 2 eyes, preoperative VA (p=0.017and p=0.007), DMD (p=0.004 and p=0.041) and final lens status (p<0.0001 and p<0.001) predicted postoperative VA. Post-hoc analysis showed significant differences in final VA between detachments of 1day vs 3 days (p=0.0009). CONCLUSION: DMD affects the final VA even among patients whose DMD is <3 days. Based on these results, interventions that shorten DMD, including those occurring within the first 3days, may result in improved long-term VA outcomes.


Assuntos
Descolamento Retiniano/fisiopatologia , Acuidade Visual/fisiologia , Idoso , Tamponamento Interno , Feminino , Fluorocarbonos/administração & dosagem , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica , Descolamento Retiniano/cirurgia , Estudos Retrospectivos , Recurvamento da Esclera , Fatores de Tempo , Resultado do Tratamento , Vitrectomia
19.
Ophthalmic Surg Lasers Imaging Retina ; 49(4): 270-272, 2018 04 01.
Artigo em Inglês | MEDLINE | ID: mdl-29664985

RESUMO

A 72-year-old female with neovascular macular degeneration refractory to anti-vascular endothelial growth factor injections underwent photodynamic therapy and subsequently developed a macular hole (MH) associated with vitreomacular traction. After a period of observation, the MH enlarged. Pars plana vitrectomy was performed, and the MH was closed successfully. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:270-272.].


Assuntos
Macula Lutea/patologia , Fotoquimioterapia/efeitos adversos , Perfurações Retinianas/etiologia , Tomografia de Coerência Óptica/métodos , Acuidade Visual , Vitrectomia/métodos , Degeneração Macular Exsudativa/tratamento farmacológico , Idoso , Feminino , Humanos , Perfurações Retinianas/diagnóstico , Perfurações Retinianas/cirurgia , Degeneração Macular Exsudativa/diagnóstico
20.
Am J Ophthalmol Case Rep ; 6: 27-29, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29260049

RESUMO

PURPOSE: To describe a patient with incontinentia pigmenti (IP) and Raynaud's phenomenon (RP). OBSERVATIONS: A 5 year-old girl with history of IP was noted to have RP. Visual acuity was unaffected in both eyes, and fundus examination demonstrated regressed peripheral neovascularization. Photos of the patient's hands demonstrated pale discoloration associated with exposure to cold. CONCLUSIONS AND IMPORTANCE: IP, known to affect small cerebral and retinal blood vessels, can also affect the small blood vessels in the extremities, resulting in secondary RP.

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