[Assessment of some metabolic parameters of white rats' liver after exposure to repetitive x-ray or microwave pulses].

Effects of repetitive X-ray and microwave pulses on the rat liver functions were investigated. The action of repetitive nanosecond X-ray is characterized by the metabolic dysfunction of the liver. In particular, it results in a considerable reduction in the ALT activity, augmentation of the AST/ALT ratio and decrease of the total protein content. The most considerable effect is observed at 16 Hz. Microwave pulses render a less significant effect on metabolic functions of the rat liver as compared to X-rays. The effect depends on the frequency of pulses.

[The self-regulation elements in the stomach secretor response to perturbing effects]. / Elementy samoreguliatsii v sekretornom otvete zheludka na vozmushchaiushchie vozdeistviia.

By the levels of stomach juice volume, its proteolytic activity, hydrogen ion activity, secreted mucus volume, the experimental dogs with stomach fistula were divided into two groups: with low and with high levels of secretion. The perturbing effects involved immobilization stress, mineral water, prolin-containing peptide Gly-Pro. One of the self-regulation mechanisms involved an "initial background rule": if the initial level of the secretion parameters is low, then it grows following the effect, whereas if it is high--it becomes lower. The rule was most evident in the stomach juice secretion complex-reflex phase.

[The baseline value of gastric secretion indices for the reactivity of the stomach secretory apparatus in response to disturbing factors]. / Znachenie iskhodnogo urovnia pokazatelei zheludochnoi sekretsii dlia reaktivnosti sekretornogo apparata zheludka v otvet na deistvie vozmushchaiushchikh faktorov.

UNLABELLED: The stomach reactivity to the impact of a number of disturbing factors depending on the baseline gastric secretion indices was examined. Fistula dogs, the secretion of which was carbacholine stimulated (6 mg/kg), were subjected to experiments. The volume of gastric secretion, proteolytic activity, activity of hydrogen ions and volume of secreted mucus were determined. Animals were divided into two groups depending on these indices during control experiments: a group with a low secretion level and a group with a high secretion level. Immobilization stress, mineral water from the lake of Shira and proline-containing peptide Gli-Pro were the disturbing factors. RESULTS: If the level of secretion parameters is low, it decreases after the impact and vice versa. The impact of the disturbing factors caused no changes at their medium volumes. This self-regulation rule became most apparent during the complex reflex stage of gastric juice secretion.

[Study of combined application of mineral water and medicinal plants as regulators of gastric secretion]. / Issledovanie sochetannogo primeneniia mineral'noi vody i lekarstvennykh rastenii v kachestve reguliatorov zheludochnoi sekretsii.

The goal of this work was to study the impact of the concurrent application of mineral water from the lake of Shira (Khakassia) and phytotherapeutic preparations on the secretory and excretory stomach functions. Mineral water from the lake of Shira belongs to highly mineralized (18.4 g/l) hydrocarbonate sodium-magnesium waters with alkaline reaction (pH 8.9). Phytotherapeutic preparations included the following herbs: common St. John's wort--4 parts (6.0 g per liter), bay willow--5 parts (7.5 g), peppermint: 5 parts (7.5 g), quinquelobate motherwort--3 parts (4.5 g), and shelf fungus--3 parts (4.5 g).

[Effect of the dry aspen bark extract on the gastric secretory function]. / Vliianie sukhogo ékstrakta kory osiny na sekretornuiu funktsiiu zheludka.

Dry aspen (Populus tremula L.) bark extract exhibits antiulcerogenic activity as demonstrated by the results of experiments using the models of gastric ulcers in rats according to H. Shay. The cytoprotective action of the dry aspen bark extract was also demonstrated in experiments on dogs with fistula according to Basov.

[Effect of Achillea asiatica Serg. on gastric secretory and excretory activity]. / Vliianie Achillea asiatica Serg. na sekretornyiu i ékskretornuiu aktivnost' zheludka.

It has been shown in chronic experiments on dogs that an extract of Achillea asiatica Serg. induces reduction of gastric juice aggressive properties (activity of proteolytic enzymes and acidity) and increase in mucus synthesis and excretory function of the stomach. The effect of the extract depends on the gastric secretion stimulator used. It reduces mainly the proteolytic activity with the use of carbo choline and the content of hydrogen ions with the use of histamine.

[Visible mucus release by different methods of stimulating gastric secretion in dogs]. / Vydelenie vidimoi slizi pri raznykh sposobakh stimuliatsii sekretsii zheludka u sobak.

Effects of meat, milk, bread, pentagastrin, histamine, carbachol and insulin upon visible mucus volume and its carbohydrate content were studied in chronic experiments on dogs.

[Secretion and excretion in the stomach exposed to hypoxia]. / Sekretsiia i ékskretsiia v zheludke pri deistvii gipoksii.

Secretion of gastric juice, pepsin, hydrochloric acid, ammonia, visible mucus and mucin, and exogenous neutral red was studied in intact dogs and in those subjected to hypoxia in a pressure chamber by rarefaction corresponding to an altitude of 7000 m. Hypoxia led to depressed secretion of pepsin, hydrochloric acid and neutral red together with a reduction in gastric juice secretion. Secretion of visible mucus and mucin was activated, whereas excretion of ammonia remained unchanged.

[Stomach secretion and excretion in mineralocorticoid deficiency]. / Sekretsiia i ékskretsiia v zheludke pri defitsite mineralokortikoidov.

Experiments on dogs were made to perform bilateral adrenalectomy and substitution therapy with hydrocortisone. Juice and acid secretion and neutral red excretion were found to be lowered after stimulation of secretion by meat and histamine. Excretion of ammonia after meat stimulation decreased, while after histamine administration it remained unchanged.

[Effect of adrenalectomy on the gastric juice secretion evoked by food or histamine in dogs]. / Vliianie adrenaléktomii na vyzvannuiu pishchei ili gistaminom sekretsiiu zheludochnogo soka u sobak.

Comparison was made of the effect of total adrenalectomy on the gastric secretion in chronic experiments on dogs with the Pavlov's stomach and Basov's fistula. A decrease of the maximal secretion level of gastric juice was associated with the alteration of the organ hemodynamics. A tendency to reduction of the acid production in the stomach was revealed. Essential differences were noted in the character of proteolytic enzymes secretion with different agents stimulating the secretion. Specific nature of the gastric secretory system for each stimulant, and different effects of adrenalectomy on the secretion induced by these stimulants was shown.