[Correlation of lactate dehydrogenase activity and its isoenzyme composition in the liver and blood serum in experimental myocardial infarction]. / Vzaimosviaz' aktivnosti laktatdegidrogenazy i ee izofermentnogo sostava v pecheni i syvorotke krovi pri éksperimental'nom infarkte miokarda.

After ligation of coronary artery an initial increase in LDH activity in liver tissue was followed by its decrease. Minimal enzymatic activity in liver tissue correlated with maximal activity in blood serum within 1-3 days. Among LDH isoenzymes the "pure" fractions were most markedly altered: LDH1 was decreased in liver tissue and increased in blood serum, LDH5 was increased in the both tissues within later periods after normalization of total activity. Enzymatic activity of LDH, LDH1 and LDH5 was shown to correlate in liver tissue and blood serum.

[Activity of key enzymes of glycolysis in the rat liver during the development of experimental myocardial necrosis]. / Aktivnost' kliuchevykh fermentov glikoliza v pecheni krolikov pri razvitii eksperimental'nogo nekroza serdechnoi myshty.

Hexokinase, glucokinase, and phosphofructokinase activity in supernatant hepatic fluid obtained by centrifugation of the homogenate at 20,000 g for 20 minutes was studied during the development of experimental necrosis of the heart muscle. The activity of these enzymes was lowest in the 12th and 24th hour following arterial occlusion. Phosphofructokinase and glucokinase activity returned to the initial level on the 6th and 9th days, respectively; hexokinase activity was still diminished after the 12th day.