[Surgical treatment of a patient over 90 years of age with abdominal aortic aneurysm]. / Khirurgicheskoe lechenie bol'nogo starshe 90 let s anevrizmoi briushnoi aorty.

Presented herein is a case of successful surgical treatment of infrarenal aortic aneurysm in a 95-year-old patient with coexistent pathology. The patient underwent replacement of the abdominal aorta with implantation of the inferior mesenteric artery. After treatment of complications which occurred in the postoperative period, the patient was discharged home in a satisfactory condition. The success of surgical treatment of infrarenal aortic aneurysm in elderly patients depends on the anesthesiological control and postoperative care of patients.

[The effect of armin on neuromuscular transmission in the frog against a background of hexadecamethonium action]. / Vliianie armina na nervno-myshechnuiu peredachu liagushki na fone deistviia geksadekametoniia.

Hexadecamethonium as well as its alkylating derivatives significantly decrease the effect of organophosphorous acetylcholinesterase inhibitor armine on the amplitude and duration of the EPPs. It seems possible that these substances prevent inhibition of acetylcholinesterase. This property of the substances seems to be due to a polymethelene chain with two nitrogens as the basic part of the molecule structure.

[The action of an alkylating analog of hexadecamethonium on neuromuscular transmission in the frog]. / Deistvie alkiliruiushchego analoga geksadekametoniia na nervno-myshechnuiu peredachu liagushki.

The treatment of m. cutaneus pectoris-n. pectoralis preparations with 0.5 microM of alkylating derivate of hexadecamethonium, hexadecamethylene-bis-methylchloroethylamine, led to irreversible decrease of the amplitude of EPPs. The decrease was shown to be of a postsynaptic nature. After pretreatment of the neuromuscular preparations with alkylating derivate the effects of cholinesterase inhibitors were strongly diminished.

[Presynaptic action of tubocurarine during frequent stimulation of a motor nerve]. / Presinapticheskoe deistvie tubokurarina pri chastoi stimuliatsii dvigatel'nogo nerva.

The dependence of the end-plate potentials inhibition upon the prevention of the muscle twitches either by tubocurarine, or alpha-neurotoxin, or cutting of the fibers was studied during nerve tetanization in the frog isolated cutaneous pectoral muscles. The decrease in end-plate potentials in the course of tetanization was the strongest under the effect of tubocurarine. The latter seems to inhibit the quantum release of acetylcholine during the nerve tetanization.

[Effect of tubocurarine on the quantum release of acetylcholine during the infrequent stimulation of a motor nerve]. / O vliianii tubokurarina na kvantovoe vydelenie atsetilkholina pri redkoi stimuliatsii dvigatel'nogo nerva.

The effect of d-tubocurarine on quantal release of acetylcholine elicited with nerve pulses 0.5 to 1 Hz was studied in the frog isolated cutaneous pectoris muscle. The muscle twitches were prevented either by lowering Ca++ and raising Mg++ or by cutting the muscle fibers. In none of these cases d-tubocurarine (3.10(-7) to 5.10(-6) M) was found to affect quantal release of acetylcholine.

[Quantitative patterns of tubocurarine action on the synaptic potentials of frog muscle]. / Kolichestvennye zakonomernosti deistviia tubokurarina na sinapticheskie potentsialy myshtsy liagushki.

The dependence of amplitude of synaptic potentials (EPP and mEPP) upon the d-tubocurarine concentration was studied in the frog cutaneous pectoral muscle. In the presence of d-tubocurarine up to 5 x 10(-7) M, the amplitude of EPP and mEPP decreased to the extent which strictly followed competitive action of d-tubocurarine. At a higher concentration, the inhibition of synaptic potentials was stronger than would be expected assuming that d-tubocurarine can only act as a competitive antagonist.