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2.
Fiziol Zh (1978) ; 36(1): 95-7, 1990.
Artigo em Russo | MEDLINE | ID: mdl-2323454

RESUMO

In the experiments on rats acute stress is found to accelerate glucose resorption by isolated loop of small intestine in situ and it probably depends on increased level of corticosteroids. Glucose resorption changes in small intestine is of adaptable character during stress.


Assuntos
Glucose/farmacocinética , Absorção Intestinal/fisiologia , Jejuno/metabolismo , Estresse Psicológico/metabolismo , Doença Aguda , Animais , Técnicas In Vitro , Masculino , Ratos , Ratos Endogâmicos , Restrição Física , Estresse Psicológico/etiologia , Fatores de Tempo
5.
Ukr Biokhim Zh (1978) ; 59(4): 97-9, 1987.
Artigo em Russo | MEDLINE | ID: mdl-2820101

RESUMO

Sodium fluoride was studied for its effect on the cAMP and cGMP amount in the small intestine mucosa of rats under conditions of acute and chronic experiments. A significant decrease in the cAMP level and an increase in the cGMP level were revealed in both cases. Changes in the content of cyclic nucleotides were followed by marked changes in their physiologically important ratios.


Assuntos
AMP Cíclico/metabolismo , GMP Cíclico/metabolismo , Mucosa Intestinal/metabolismo , Intestino Delgado/metabolismo , Fluoreto de Sódio/farmacologia , Animais , Mucosa Intestinal/efeitos dos fármacos , Intestino Delgado/efeitos dos fármacos , Ratos
6.
Ukr Biokhim Zh (1978) ; 59(3): 23-8, 1987.
Artigo em Russo | MEDLINE | ID: mdl-2955555

RESUMO

Effect of NaF on ATP-ase, creatine kinase, acid and basic phosphatases activity of small intestine mucosa in white rats during enteral administration of NaCl, KCl solutions has been studied under conditions of acute experiment. Inhibition of the Mg2+-ATP-ase activity by 13%, general ATP-ase activity by 25%, creatine kinase by 22% and a 2.2-3 fold inhibition of Na, K+-ATP-ase activity is observed. Acid and basic phosphatase activity does not change, swelling of mucosa is observed. The acid phosphatase activity in the intestinal contents increases 1.5 times, basic phosphatase activity--1.7 times, creatine amount--1.7 times, Pi amount 1.8 times. In experiments in vitro F- produces 20% activation of the basic phosphatase of mucosa and a 2.6-fold inhibition of the acid phosphatase. Rate of fructose absorption falls by 34%, that of methionine--by 29%, glucose--by 24%, glutaminic acid--by 10%. Activity of general ATP-ase in this case decreases by 22, 15, 27, 20% respectively. It is supposed that the F- effect results in destabilization of the membrane structures of the intestine mucosa.


Assuntos
Flúor/farmacologia , Absorção Intestinal/efeitos dos fármacos , Mucosa Intestinal/enzimologia , Intestino Delgado/enzimologia , Fosfatase Ácida/metabolismo , Adenosina Trifosfatases/metabolismo , Fosfatase Alcalina/metabolismo , Aminoácidos/metabolismo , Animais , Transporte Biológico/efeitos dos fármacos , Creatina Quinase/metabolismo , Mucosa Intestinal/metabolismo , Intestino Delgado/metabolismo , Cinética , Masculino , Monossacarídeos/metabolismo , Potássio/metabolismo , Ratos , Sódio/metabolismo
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