[Functional state of the liver during development of extrahepatic cholestasis and during use of enterosorption]. / Funktsional'noe sostoianie pecheni v khode razvitiia vnepechenochnogo kholestaza i pri primenenii énterosorbtsii.

Use of enterosorption during the first week of extrahepatic cholestasis in rats led to decrease of disorders in functional state of liver tissue and its subcellular organelles as well as of accumulation of toxic substances in organism. The main effect of enterosorption appears to be binding of Gram-negative bacteria endotoxin in intestine.

[Response of subcellular structures of the dog liver to hemosorption in different stages of extrahepatic cholestasis]. / Reaktsiia subkletochnykh struktur pecheni sobak na provedenie gemosorbtsii v razlichnye étapy ékstrapechenochnogo kholestaza.

It was established in experiments on dogs that the effect of hemosorption on the mitochondrial apparatus and the lysosomal system of the hepatic cells in extrahepatic cholestasis depends on the stage of the pathological process and the corresponding prehemosorption condition of the subcellular structures.

[Efficacy of the combined use of lipid- and water-soluble bioantioxidants (vitamins E, A and C)]. / Effektivnost' sovmestnogo primeneniia lipido- i vodorastvorimykh bioantioksidantov (vitaminov E, A i C).

Experiments on noninbred male rats were made to show appreciable differences in the effect of the isolated and combined use of vitamins E, A and C. This was manifested in the changes of tocopherol and ascorbic acid capacity of accumulation and utilization by the liver, of dissimilar effects on the contend of lipid peroxidation products and respiratory function of the mitochondria.