The petrous portion of the temporal bone as shown on sonography between 14 and 40 weeks' gestation.

OBJECTIVES: The purpose of this study was to examine the feasibility of sonographically identifying, measuring, and constructing nomograms of the fetal petrous bone, the part of the temporal bone that houses the auditory apparatus. METHODS: A total of 248 consecutive pregnant women between 14 and 40 weeks' gestation were included. During a routine scan using transvaginal or transabdominal sonography, the fetal head was assessed in transverse sections. First, the parotid gland or external ear was identified, followed by the petrous bone. This annular echogenic structure, located medially and superior to the parotid gland or external ear, was measured at its largest anteroposterior diameter. The petrous bone on at least one side was measured; if both sides were visualized easily, both petrous bones were measured. RESULTS: In 247 fetuses, at least one petrous bone was measured. The petrous bone measurement correlated well with the gestational age (R = 0.908; P < .001), biparietal diameter (R = 0.983; P < .001), and femur length (R = 0.913; P < .001). CONCLUSIONS: Depiction of the petrous bone is feasible at all gestational ages and correlates well with the gestational age, biparietal diameter, and femur length. The usefulness of the ability to depict this bone in prenatal diagnosis of congenital malformations of the inner ear should be tested in prospective studies.

Placental volume and three-dimensional power Doppler analysis in prediction of pre-eclampsia and small for gestational age between Week 11 and 13 weeks and 6 days of gestation.

OBJECTIVE: To assess three-dimensional placental volume measurement and three-dimensional power Doppler (3D-PD) indices between 10 weeks and 6 days and 13 weeks and 6 days in predicting pregnancy-induced hypertension (PIH) and small for gestational age (SGA). METHODS: Three hundred and eight women undergoing fetal nuchal translucency measurement were prospectively assessed using three-dimensional ultrasound in order to measure placental volume and 3D-PD indices: vascularization index (VI), flow index (FI) and vascularization flow index (VFI), using the VOCAL software. The outcome was scored as normal, PIH, SGA or both. RESULTS: Eight women developed PIH and ten delivered SGA; and 17 developed PIH or SGA. The age, gestational age at the examination or delivery, number of the pregnancy and the nuchal translucency, were similar in all groups. The placental volume, FI and VFI were similar between the groups. The VI was significantly lower when PIH developed (7.86 ± 3.92 vs. 12.02 ± 7.09 in the normal group, P = 0.035). The crown-rump length (CRL) was significantly smaller in the group where either PIH or SGA developed compared to normal outcome (54.29 ± 6.50 and 59.04 ± 8.89, respectively, P = 0.02). CONCLUSION: Placental volume is not appropriate for early prediction of PIH or SGA, whereas the VI may be of some potential in detection of PIH. The significance of small CRL in these patients should be further tested.

Gestational sac volume in missed abortion and anembryonic pregnancy compared to normal pregnancy.

PURPOSE: To compare gestational sac (GS) volume (GSV) between normal pregnancies and missed abortions and anembryonic pregnancies and to determine at what gestational age differences in GS volume become evident. METHODS.: GSV in missed abortion and anembryonic pregnancy were measured using three-dimensional ultrasound and the results were compared with GSV in normal pregnancies. Pregnancies between 6 and 12(+6) gestational weeks of age according to last menstrual period were included in normal pregnancies, missed abortions, and anembryonic pregnancies. RESULTS: There were 141 normal pregnancies and 82 missed or anembryonic abortions. GSV was significantly larger in normal pregnancies than in missed or anembryonic abortion: 27.51 + or - 25.25 cm(3) and 8.04 + or - 10.54 cm(3), respectively (p < 0.001). When stratified by weeks, statistically significant differences were found beginning at 7 weeks, while GSV measurements were not significantly different between the normal and abnormal pregnancies from 6 to 6(+6) weeks. CONCLUSION: GSV in missed abortion and anembryonic pregnancies is significantly smaller than in normal pregnancies, starting at 7 weeks of gestational age. This finding may be helpful in the diagnosis of missed abortion or anembryonic pregnancies in selected cases.

Fetal eyeball volume: relationship to gestational age and biparietal diameter.

OBJECTIVE: To measure and determine normal values of the fetal eyeball volume between 14 and 40 weeks of gestation. METHODS: The volume of the fetal eyeball was measured with three-dimensional ultrasound between 14 and 40 weeks of gestation using the VOCAL software.Only singleton pregnancies without fetal growth restriction, diabetes mellitus, hypertension or major fetal malformation were included. RESULTS: Over all, 203 women were studied. In 125 both eyeballs were measured while in 78 only one eyeball was measured. The volume of the eyeball correlated strongly with gestational age (right: R = 0.946, P < 0.001, n = 171. left: R = 0.945, P < 0.001, n = 156), and with the biparietal diameter (BPD) (right: R = 0.949, P < 0.001, n = 171. left: R = 0.953, P < 0.001, n = 156). Using regression analysis the best correlation between eyeball volume and the BPD were: square of right eyeball = -0.180 + 0.187 BPD, square of left eyeball = -0.182 + 0.187 BPD. CONCLUSIONS: The volume of the eyeball has strong positive correlations with gestational age and BPD. Our data may be helpful in fetuses suspected of having eye anomalies.