RESUMO
Studies have been made on the lipid composition of total lipids, triglycerides and their fatty acids, cholesterol and phospholipids in the vertebral column of young and adult rabbits. It was shown that the content of total lipids and triglycerides increases, whereas that of cholesterol and phospholipids decreases with age. The content of total lipids in the vertebral column is 10 times higher as compared to that in the bones of the extremities. Mid-thoracic part of the vertebral column exhibits higher lipid content than other thoracic parts of the column. Lipid content of the vertebral processes is lower than that of the vertebral bodies. These data indicate lipid specificity and heterogeneity of bone tissue of the vertebral column. The main fatty acids of vertebral triglycerides are presented by those with 14-18 carbon atoms (90%), no acids with 22 atoms were found. Higher content of the linoleic acid (19%) and higher total unsaturation of triglycerides were found in the bone tissue of rabbits in comparison with those of man.
Assuntos
Envelhecimento/metabolismo , Osso e Ossos/análise , Lipídeos/análise , Coluna Vertebral/análise , Animais , Colesterol/análise , Ácidos Graxos/análise , Fosfolipídeos/análise , Coelhos , Triglicerídeos/análiseRESUMO
Deveropment of experimental scoliosis in rabbits, produced by single-side rhizotomia at Th5-Th9, was accompained by accumulation of hexoses, hexoseamines and collagen in corpus vertebrae and in processus spinosus of the primary arch of curvature within all the periods of observation (23 months) as well as by an increase in content of calcium and phosphorus, occurring at the period of the scoliosis complete stabilization (10-11 months). Similar, although less distinct, alterations were found in the compensatory arch of curvature.