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1.
Theory Biosci ; 135(4): 187-200, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-27443312

RESUMO

After an introduction to the general topic of models for a given locus of a diploid population whose quadratic dynamics is determined by a fitness landscape, we consider more specifically the models that can be treated using genetic (or train) algebras. In this setup, any quadratic offspring interaction can produce any type of offspring and after the use of specific changes of basis, we study the evolution and possible stability of some examples. We also consider some examples that cannot be treated using the framework of genetic algebras. Among these are bistochastic matrices.


Assuntos
Evolução Biológica , Modelos Genéticos , Algoritmos , Alelos , Diploide , Genótipo , Recombinação Genética , Seleção Genética , Processos Estocásticos
2.
Environ Technol ; 31(13): 1441-7, 2010 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-21214003

RESUMO

This paper reviews some catalytic wet air oxidation (CWAO) investigations of industrial wastewaters over platinum and ruthenium catalysts supported on TiO2 and ZrO2 formulated to be active and resistant to leaching, with particular focus on the stability of the catalyst. Catalyst recycling experiments were performed in batch reactors and long-term stability tests were conducted in trickle-bed reactors. The catalyst did not leach upon treatment of Kraft bleaching plant and olive oil mill effluents, and could be either recycled or used for long periods of time in continuous reactors. Conversely, these catalysts were rapidly leached when used to treat effluents from the production of polymeric membranes containing N,N-dimethylformamide. The intermediate formation of amines, such as dimethylamine and methylamine with a high complexing capacity for the metal, was shown to be responsible for the metal leaching. These heterogeneous catalysts also deactivated upon CWAO of sewage sludges due to the adsorption of the solid organic matter. Pre-sonication of the sludge to disintegrate the flocs and improve solubility was inefficient.


Assuntos
Ar , Resíduos Industriais , Metais/química , Esgotos , Poluentes da Água/química , Catálise , Oxirredução
3.
Mol Psychiatry ; 14(10): 959-67, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19255582

RESUMO

Adult hippocampal neurogenesis is a unique example of structural plasticity, the functional role of which has been a matter of intense debate. New transgenic models have recently shown that neurogenesis participates in hippocampus-mediated learning. Here, we show that transgenic animals, in which adult hippocampal neurogenesis has been specifically impaired, exhibit a striking increase in anxiety-related behaviors. Our results indicate that neurogenesis plays an important role in the regulation of affective states and could be the target of new treatments for anxiety disorders.


Assuntos
Ansiedade/fisiopatologia , Hipocampo/fisiologia , Neurogênese/fisiologia , Animais , Ansiedade/tratamento farmacológico , Comportamento Animal/efeitos dos fármacos , Comportamento Animal/fisiologia , Contagem de Células , Clordiazepóxido/farmacologia , Depressão/fisiopatologia , Doxiciclina/farmacologia , Hipocampo/efeitos dos fármacos , Hipocampo/metabolismo , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Camundongos Transgênicos , Neurogênese/efeitos dos fármacos , Neurogênese/genética , Neurônios/citologia , Neurônios/efeitos dos fármacos , Neurônios/metabolismo , Proteína X Associada a bcl-2/genética , Proteína X Associada a bcl-2/metabolismo
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