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J Pediatr Hematol Oncol ; 37(7): e438-40, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26207780

RESUMO

In a patient with sickle cell disease receiving chronic transfusion, exacerbation of anemia with reticulocytopenia must prompt consideration of a delayed hemolytic transfusion reaction with hyperhemolysis, as further transfusion may worsen this condition; definitive diagnosis is sometimes difficult. Anemia evolving during parvovirus B19-induced erythroid hypoplasia (transient aplastic crisis) should be attenuated in chronic transfusion patients due to superior survival of transfused over endogenous red blood cells. A 16-year-old with sickle cell disease receiving chronic transfusion of modified intensity (goal to maintain hemoglobin S<50%) who developed symptomatic anemia with reticulocytopenia was later shown to have had transient aplastic crisis.


Assuntos
Anemia Falciforme/terapia , Anemia/etiologia , Transfusão de Eritrócitos/efeitos adversos , Reticulócitos/patologia , Reação Transfusional/etiologia , Adolescente , Feminino , Humanos , Contagem de Reticulócitos , Reação Transfusional/patologia
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