RESUMO
Blood donors who were tested twice at interval from 6 to 8 months, were HBs-Ag positive both times. The biochemical parameters for the evaluation of liver function were within normal limits. The significantly decreased values of total haemolytic activity of complement-CH50 (0,001) and Clq (0,005) and increased level of Cl Inh (0,005) point ot the activation of the complement system (Table 2, 3). The level of Cl Inh statistically significantly and positively correlates with the values of C4, C5 and with C3A, what means that it participates in the process of activation regulation (Table 5). Using the method of precipitation by means of 0,3 g/l PEG we have registered in 92% of HBs-Ag positive blood donors elevated concentrations of immune complexes and in all PEG precipitates HBs-Ag (Table 6). These findings point to the need of clinical investigation and treatment of those persons.
Assuntos
Complexo Antígeno-Anticorpo/análise , Doadores de Sangue , Proteínas do Sistema Complemento/análise , Antígenos de Superfície da Hepatite B/análise , Adolescente , Adulto , HumanosRESUMO
From 402 pregnant women immunized with blood-group antigens, the anamnestic serologico-immunological reaction has been confirmed in 11 cases (2,7%). Because of the absolute low number of the cases that have been followed up no suggestions are suggested but only observations made with the invitation to professionals to follow up, in an organized form, this interesting phenomenon in blood group immunology.