[Levels of serotonin in plasma and activity of monoamine oxidase in serum and blood platelets of women with EPH gestosis]. / Stezenie serotoniny w osoczu i aktywnosc monoaminooksydazy w surowicy i plytkach krwi u kobiet w ciazy powiklanej EPH gestoza.

The study was performed on 70 pregnant women, divided into two groups: normal or EPH gestosis. The concentration of serotonin in plasma was determined according to Manuchin et al., the activity of monoamine oxidase was determined using the radioisotope method of Yuodim. Daily urinary excretion of 5-hydroxyindoleacetic acid was established with the method of Udenfriend et al. It was found that women with EPH gestosis have significantly higher (p < 0.01) plasma concentration of serotonin and significantly lower activities of MAO (p < 0.001) in serum and in blood platelets and urinary excretion of 5-hydroxyindoleacetic acid (p < 0.05) than normal pregnant women.