Visual loss as the initial manifestation of an ignored disseminated prostate cancer: A case report.

Purpose: To present a rare case of advanced disseminated prostate cancer with bilateral visual loss as the initial manifestation of the disease. Observations: A 55-year-old man referring progressive visual blurring for the last 6 months and painless severe bilateral visual loss in the last 7 days prior to our consultation, associated with a bilateral optic disc swelling and leptomeningeal metastases from a previously ignored prostate carcinoma is presented. Rapid improvement of visual acuity and involution of leptomeningeal metastasis was observed after initiation of the specific oncologic treatment. Conclusions and importance: Bilateral visual loss may be the initial manifestation of leptomeningeal carcinomatosis from an ignored prostate cancer. Prompt diagnosis is crucial in order to improve the quality of life of a critically ill patient with a disseminated prostate cancer.

Drusen de papila. Análisis descriptivo / Papillary drusen. Descriptive analysis

INTRODUCCIÓN: Los drusen de papila son depósitos de material hialino calcificado a nivel de la cabeza del nervio óptico. Pueden ser difíciles de distinguir de la verdadera inflamación del nervio óptico y su identificación correcta es relevante debido a la morbilidad visual y sistémica que conlleva el diagnóstico de un verdadero edema de papila. OBJETIVO: Describir los hallazgos clínicos en un grupo de pacientes con drusen de papila. MATERIAL Y MÉTODO: Estudio descriptivo retrospectivo de 39 casos de pseudoedema de papila secundario a drusen de papila. Se recuperaron datos de la historia clínica y se analizaron características oftalmológicas y de los métodos complementarios (campo visual computarizado ­CVC-, tomografía de coherencia óptica ­OCT- , ecografía y neuroimágenes). RESULTADOS: Se estudiaron 39 ojos. La edad promedio al diagnóstico fue de 9 años. La mayoría no reporto antecedentes patológicos ni heredofamiliares. El principal motivo de consulta fue control de rutina y el segundo fue cefalea. El 56% tenían una excelente agudeza visual, 20% buena, 2.5% regular y 5% mala agudeza visual. El 36% de los ojos fueron emétropes, 41% hipermétropes y 23% miopes. Los hallazgos más representativos en el fondo de ojos fue la sobreelevación papilar (71,8% IC95% 57,9-86), papila de bordes borrados (43% IC95% 27,4-58,5) y tortuosidad vascular (43,6% IC95% 27,4-58,5). En todos los casos la ecografía fue diagnóstica, mostrando imágenes hiperecoicas dentro del nervio óptico. En el CVC no se encontraron hallazgos relevantes. CONCLUSIONES: Los drusen de papila son una alteración que puede encontrarse con frecuencia en un examen de fondo de ojo de rutina, y que un oftalmólogo debe conocer para evitar errores diagnósticos. (AU)

INTRODUCTION: Papillary drusen are deposits of calcified material at the level of the optic nerve head. It's can be difficult to distinguish from true optic nerve swelling. Its correct identification is relevant due to the visual and systemic implications of the diagnosis of true papilledema. OBJECTIVE: To characterize clinically a group of patients diagnosed with papillary drusen. MATERIAL AND METHODS: A retrospective descriptive study of 39 eyes with papillary pseudoedema secondary to optic nerve drusen was performed. Data from the medical history were retrieved and characteristics of the ophthalmological medical examination and complementary methods such as optical coherence tomography (OCT), computerized visual fields, and ocular ultrasound were analyzed. RESULTS: 39 eyes of 20 patients with papillary drusen were studied. The average age at diagnosis was 9 years. The majority did not report pathological or heredofamilial background. The main complain consultation was routine check out and the second was headache. The 56% had excellent visual acuity, 20% good, 2.5% regular and 5% had poor visual acuity. There were 36% emmetropic eyes, 41% hypermetropics and 23% myopia. The most representative findings in the fundus were swollen disks, appearing in (71,8% IC95% 57,9-86) of the cases, optic nerve with ill-defined and vascular tortuosity, appeating in 43,6% (IC95% 27,4-58,5) of the cases. In all cases the ultrasound was diagnostic, showing hyperechoic images withing the optic nerve. No relevant findings were found at CVC. CONCLUSIONS: Papillary drusen is a frequent disease that can be found in every day practice. Ophthalmologist should be aware of this to avoid misdiagnosis. (AU)