[Echocardiographic diagnosis of acute rejection of transplanted heart]. / Ekhokardiograficheskaia diagnostika ostrogo ottorzheniia peresazhennogo serdtsa.

Comparing echocardiographic parameters with endomyocardial biopsy findings in 6 patients with acute crises of mild, moderate, and severe graft rejections and in 2 patients with persistent acute rejection crisis has shown that there are decreases in end-diastolic size and left ventricular end-diastolic ejection fraction volume, an increase in left ventricular myocardial mass, and thickening of the left ventricular posterior wall and ventricular septum, as evidenced by ultrasonic study. Such changes are detected in moderate and severe acute crises of graft rejection. Normalization of ultrasonic parameters of the grafted heart occurs 2-3 weeks after abolition of rejection crisis. A positive dynamics of echocardiographic parameters in persistent acute rejection crises suggests a good prognosis. Echocardiographic monitoring data obtained in the outpatient setting may serve an indication for unplanned endomyocardial biopsy.

[The determination of erythrocyte deformability using a filtration method]. / Otsenka deformabel'nosti éritrotsitov metodom fil'tratsii.

Red cell deformability was assessed in donors, patients with chronic renal insufficiency, and with thermal injuries by filtration through special filters. Filtration of donor red cells decreased their count but insignificantly; in patients with chronic renal insufficiency this characteristic was lowered, particularly so before hemoperfusion, whereas after hemoperfusion red cell deformability improved. Changes of red cell deformability in patients with thermal injuries is an objective criterion reflecting the status of the erythron peripheral component in connection with the severity of injury and course of its healing.

[Surface architectonics and erythrocyte deformability in patients with terminal stage of chronic kidney failure]. / Poverkhnostnaia arkhitektonika i deformiruemost' éritrotsitov u bol'nykh s terminal'noi stadiei khonicheskoi pochechnoi nedostatochnosti.

Red cell deformability was examined in donors and patients with chronic renal insufficiency; the red cell surface architectonics before and after filtration was under study. The red cell ability to deformation was found reduced in the patients, the level of nontransitional prehemolytic forms of red cells increased, and the count of discoid cells reduced. These data permit assessing the red cell ability to deformation.

[A device for determining erythrocyte deformability]. / Ustroistvo dlia opredeleniia deformabel'nosti éritrotsitov.

A device for determining red cell deformability is described. The studies have demonstrated that in normal subjects the red cell deformability is sufficiently high and the cells penetrate through a filter with pore diameter of 5 microns, whereas in the patients with chronic renal insufficiency this parameter is reduced (p less than 0.001).