Reproductive disorders, osteoporosis and secondary hyperparathyroidism with celiac disease.

A clinical observation of a patient with celiac disease, aged 23, with severe form of osteoporosis, accompanied by atraumatic fractures bones, lameness, late onset of menstruation and pathology of pregnancy is described. It is emphasized that only a timely diagnosis celiac disease and timely prescribed treatment make it possible to avoid severe complications.

[The effect of an agluten diet on cellular immunity in adult patients with celiac disease]. / Vliianie agliutenovoi diety na pokazateli kletochnogo immuniteta u bol'nykh tseliakiei vzroslykh.

A total of 45 patients with Gee's disease of adults were followed up in the time course of 6 months to 3 years. In untreated patients the number of T-lymphocytes was decreased both at the expense of T-helpers and, especially, of T-suppressors. Lymphokine-producing activity of T-lymphocytes, according to the production degree of the mediator, inhibiting monocyte adherence, increases after gliadin-treatment of the immuno-competent cells, that leads to monocyte adhesion decrease. In patients strictly keeping the agluten diet the cellular immunity parameters return to normal. Decreased monocyte adhesion remains up to a year. In those who do not strictly keep the agluten diet the cellular immunity disorders are retained and become more pronounced than in the untreated patients.