Mixed-methods evaluation of a group psychosocial intervention for refugee, migrant and host community women in Ecuador and Panamá: Results from the Entre Nosotras cluster randomized feasibility trial.

Community-based psychosocial interventions are key elements of mental health and psychosocial support; yet evidence regarding their effectiveness and implementation in humanitarian settings is limited. This study aimed to assess the appropriateness, acceptability, feasibility and safety of conducting a cluster randomized trial evaluating two versions of a group psychosocial intervention. Nine community clusters in Ecuador and Panamá were randomized to receive the standard version of the Entre Nosotras intervention, a community-based group psychosocial intervention co-designed with community members, or an enhanced version of Entre Nosotras that integrated a stress management component. In a sample of 225 refugees, migrants and host community women, we found that both versions were safe, acceptable and appropriate. Training lay facilitators to deliver the intervention was feasible. Challenges included slow recruitment related to delays caused by the COVID-19 pandemic, high attrition due to population mobility and other competing priorities, and mixed psychometric performance of psychosocial outcome measures. Although the intervention appeared promising, a definitive cluster randomized comparative effectiveness trial requires further adaptations to the research protocol. Within this pilot study we identified strategies to overcome these challenges that may inform adaptations. This comparative effectiveness design may be a model for identifying effective components of psychosocial interventions.

Alteraciones lipoproteicas en trabajadores expuestos a bisulfuro de carbono / Lipoproteinic alterations in workers exposed to carbon bisulphide

Se estudiaron 99 trabajadores de la fábrica de rayón viscoso "Gonzalo Quesada", de la provincia de Matanza, expuestos a diferentes concentraciones de bisulfuro de carbono, agrupándolos por edad y tiempo de exposición.Se les hizo exámen médico, determinaciones en suero de colesterol, triglicéridos, glucosa y electroforesis de lipoproteínas. Además, se realizó un estudio químico para determinar las concentraciones de bisulfuro de carbono en aire, en las diversas áreas de trabajo. Al comparar los resultados de los distintos grupos, seencontró en los trabajadores de las áreas de mayor concentración de bisulfuro carbono, menores de 50 años de edad y con 5 ó más años de exposición, diferenciassignificativas en las betalipoproteínas, prebeta lipoproteínas y quilomicrones,también un aumento en las concentraciones de colesterol y triglicéridos (AU)