RESUMO
Synthetic culture medium containing potato starch and 1 gm% sucrose, with and without human parotid saliva, were pre-incubated. Filtrates from these mixtures were then incubated with Streptococcus mutans. S. mutans colonization on glass rods was suppressed in the cultures using filtrates from saliva and starch interaction. No inhibition was noted in filtrates pre-treated with parotid saliva in the absence of starch. The results suggest that the hydrolysis of starch by saliva yields by-products which inhibit in vitro S. mutans colonization.
Assuntos
Saliva/fisiologia , Amido/metabolismo , Streptococcus mutans/efeitos dos fármacos , Adesividade , Humanos , Hidrólise , Maltose/farmacologia , Amido/farmacologia , Streptococcus mutans/citologia , Sacarose/metabolismoRESUMO
The comparative and combined effects of sucrose, maltose, and lactose as factors on the plaque-forming potential of Streptococcus mutans were assessed. With increasing additions of maltose to sucrose-supplemented medium there was decreasing plaque formation. Lactose additions slightly increased plaque formation, but when combined with maltose they significantly enhanced the maltose inhibition of plaque formation.