RESUMO
INTRODUCTION: Earthworms respond to microbial infection through cellular and humoral defense mechanisms such as antimicrobial protein secretions. Most of the humoral defense proteins are synthesized in the skin itself. MATERIALS AND METHODS: In the present study, a dried powder was prepared from two indigenous earthworms (Lampito mauritii and Perionyx excavatus) and tested against two gram-positive bacteria (Staphylococcus aureus and Staphylococcus epidermidis) and five gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Proteus vulgaris, and Pseudomonas aeruginosa). RESULTS: The dried earthworm powder of two species shows a strong antibacterial activity against the S. aureus, P. mirabilis, and P. aeruginosa bacterial strains. Of these, the 60 µg/mL/disc of P. excavatus earthworm powder shows more activity than the L. mauritii.
