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Purpose This study aims to assess the significance of imaging techniques and needle thickness employed in transthoracic core needle biopsy for determining the cancer type and subtypes, ultimately guiding the treatment of lung cancer. Material and methods Between 2018 and 2023, a cohort of 350 patients (69.7% male, 30.3% female) underwent CT-guided lung biopsy, predominantly utilizing core biopsies. Fine needle aspiration biopsies employed 18 or 20 G Chiba needles, while core needle biopsies utilized 16 or 18-gauge coaxial system semi-automatic needles. The preferred needle and biopsy sample size were 16 G in thickness and 2 cm in length. Pre-procedure positron emission tomography-computed tomography (PET-CT) images aided in identifying the most homogenous lesion with the highest SUV max value, guiding biopsy sample extraction. Post-procedure control CT evaluated complications according to the Society of Interventional Radiology (SIR) reporting standard. Results The average age of biopsied patients was 65.48 +/- 12.32 SD (range: 18-90). Tru-cut biopsy was predominant (69.7%), utilizing a larger number of 16G needles. Pathological diagnoses were mostly malignant (76.6%), with lesion sizes averaging 35.98 +/- 17.90 SD (range: 5-105 mm) and distances to pleura averaging 13.48 +/- 13.54 SD (range: 0-86 mm). Malignancy prevalence was higher in males (56.8%), tru-cut biopsies (72.7%), 16G needles used for tru-cut (47.7%), and PET-CT evaluation (59.1%). Complications were identified in 22% of cases, with distance to pleura significantly associated (p < 0.001). No significant differences in complication risk were observed between FNAB and tru-cut and between needle gauges (20 G-18 G and 16 G) (p: 0.734, p: 0.638, respectively). Conclusion The study underscores the paramount importance of biopsy sample size in diagnosing lung cancers and determining targeted therapy. Optimal biopsy localization, informed by pre-procedure imaging techniques, is crucial. Hence, the recommendation is to utilize the thickest needles and largest samples for lung biopsies.
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AIM: The aim of this study was to evaluate rib fracture-related complications in blunt chest traumas. METHODOLOGY: The study included a cohort of 132 male and 42 female patients, aged between 22 and 89 years, all diagnosed with rib fractures subsequent to blunt chest trauma. The data collection period extended from November 2017 to November 2019. Pulmonary complications, including pneumothorax, hemothorax, pulmonary contusion, flail chest, and the need for mechanical ventilator support, were retrospectively evaluated based on age, gender, trauma history, bilateral fractures, the number of fractured ribs, and concomitant traumas in other systems. Patients with one or two fractured ribs were included in Group 1, while those with three or more rib fractures were in Goup 2. RESULTS: Patients in Group 2 (n=82) had a significantly higher mean age and complication rate compared to patients in Group 1 (56.24 vs. 51.08; p: 0.033; p=0.000). Falls from height were the most common trauma history. The most frequently broken ribs were the fifth right (n=35) and the ninth right ribs (n=35), followed by the seventh right (n=33) and the seventh left rib (n=32) in order. Pneumothorax was diagnosed in 60 patients (34.4%), hemothorax in 48 patients (27.5%), and pulmonary contusion in 22 patients (12.6%). Seven patients had a flail chest (4.0%) and four required mechanical ventilation support. The number of male patients was significantly higher (p=0.000). Motor vehicle accidents were most correlated with complications in trauma history (p=0.002). Elderly age, bilateral fractures, three or more fractured ribs, and the mechanism of trauma were significantly correlated with complications (p < 0.05). The mortality rate was 0%. CONCLUSION: Three or more fractured ribs, bilateral fractures, and high-energy traumas are important risk factors, particularly in the elderly population. For patients meeting these criteria, hospitalization and careful observation are recommended.
